Circulating microRNAs in Fabry Disease

Autor: Ke Xiao, Dongchao Lu, Jeannine Hoepfner, Laura Santer, Shashi Gupta, Angelika Pfanne, Sabrina Thum, Malte Lenders, Eva Brand, Peter Nordbeck, Thomas Thum

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)

Abstract Fabry disease is an X-linked deficiency of the lysosomal hydrolase alpha-galactosidase A (alpha-Gal). This results in an accumulation of globotriaosylceramide (GL-3/Gb3) in a variety of cells with subsequent functional impairment. The contin

Externí odkaz: https://doaj.org/article/875154d0910d4335b4c8cf600b0c2de4

Hypoxic preconditioning of macrophages as therapeutic strategy for ischemic cardiac injury

Autor: Marida Sansonetti, Florian Waleczek, Sabrina Thum, Angelika Pfanne, Annette Just, Mira Jung, Thomas Thum

Publikováno v: Journal of Molecular and Cellular Cardiology. 173:74-75

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2806ae9edd33e35fe46c545a63cb2832
https://doi.org/10.1016/j.yjmcc.2022.08.151

Circulating microRNA-132 levels improve risk prediction for heart failure hospitalization in patients with chronic heart failure

Autor: Serge Masson, Sandor Batkai, Julia Beermann, Christian Bär, Angelika Pfanne, Sabrina Thum, Michela Magnoli, Giovanna Balconi, Gian Luigi Nicolosi, Luigi Tavazzi, Roberto Latini, Thomas Thum

Publikováno v: European Journal of Heart Failure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::7dea8858aee52c55eda1b812738041c5

Preclinical Development of a MicroRNA-Based Therapy for Elderly Patients With Myocardial Infarction

Autor: Sebastian Preissl, Florence Pinet, Karina Zimmer, Pascal de Groote, Shashi Kumar Gupta, Sabrina Thum, Thomas Thum, Leon J. De Windt, Christophe Bauters, Reinier A. Boon, Janet Remke, Lutz Hein, Ariana Foinquinos, Sandor Batkai

Publikováno v: Journal of the American College of Cardiology
Journal of the American College of Cardiology, 2016, 68 (14), pp.1557-1571. ⟨10.1016/j.jacc.2016.07.739⟩
Journal of the American College of Cardiology, Elsevier, 2016, 68 (14), pp.1557-1571. ⟨10.1016/j.jacc.2016.07.739⟩
Gupta, S K, Foinquinos, A, Thum, S, Remke, J, Zimmer, K, Bauters, C, de Groote, P, Boon, R A, de Windt, L J, Preissl, S, Hein, L, Batkai, S, Pinet, F & Thum, T 2016, ' Preclinical Development of a MicroRNA-Based Therapy for Elderly Patients With Myocardial Infarction ', Journal of the American College of Cardiology, vol. 68, no. 14, pp. 1557-71 . https://doi.org/10.1016/j.jacc.2016.07.739
Journal of the American College of Cardiology, 68(14), 1557-1571. Elsevier Science
Journal of the American College of Cardiology, 68(14), 1557-71. Elsevier USA

BACKGROUND: Aging populations show higher incidences of myocardial infarction (MI) and heart failure (HF). Cardiac remodeling post-MI leads to progressive impaired cardiac function caused by a disarray of several processes including derailed autophag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755dbb5b3d82ebec5c58137241ecb3ab
https://pubmed.ncbi.nlm.nih.gov/28251131

Deregulation of microRNA-181c in cerebrospinal fluid of patients with clinically isolated syndrome is associated with early conversion to relapsing-remitting multiple sclerosis

Autor: Martin Stangel, Corinna Trebst, Hayrettin Tumani, Angelika Pfanne, Romy Roesler, Filippo Martino, Refik Pul, Uwe K. Zettl, Jonas Ahlbrecht, Özlem Yildiz, Thomas Skripuletz, Lars Tasto, Thomas Thum, Sabrina Thum, Florian Lauda, Kurt-Wolfram Sühs, Celina Schauerte, Michael Hecker

Publikováno v: Multiple sclerosis (Houndmills, Basingstoke, England). 22(9)

Background: MiRNA-181c, miRNA-633 and miRNA-922 have been reported to be deregulated in multiple sclerosis. Objectives: To investigate the association between miRNA-181c, miRNA-633 and miRNA-922 and conversion from clinically isolated syndrome (CIS)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f7b2504f691d95e9485e147ef29100
https://pubmed.ncbi.nlm.nih.gov/26493127