Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sabrina Solouki"'
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
IL-10+Tr1 cells, which do not express stable Foxp3 like conventional Treg cells, are associated with various diseases, but little is known about how their differentiation and function are regulated. Here the authors show that ITK is a central TCR sig
Externí odkaz:
https://doaj.org/article/eb63136b19fd40fbb0f60255832a0ecd
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/0a99219c27144071be43a613a3655986
Beyond Type 1 Regulatory T Cells: Co-expression of LAG3 and CD49b in IL-10-Producing T Cell Lineages
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Type 1 regulatory CD4+ T (Tr1) cells express high levels of the immunosuppressive cytokine IL-10 but not the master transcription factor Foxp3, and can suppress inflammation and promote immune tolerance. In order to identify and obtain viable Tr1 cel
Externí odkaz:
https://doaj.org/article/efea5d67bc1e4c999829a576c3ea0750
Publikováno v:
The Journal of Immunology. 205:1217-1227
CD8+ T cells play a critical role in adaptive immunity, differentiating into CD8+ memory T cells that form the basis of protective cellular immunity. Vaccine efficacy is attributed to long-term protective immunity, and understanding the parameters th
Autor:
Michael C McGee, Sabrina Solouki, Candice B Limper, Tianyi Zhang, Nicholas Magazine, Kaixiong Ye, Natalie Nidetz, Avery August, Weishan Huang
Publikováno v:
The Journal of Immunology. 208:55.20-55.20
Influenza (flu) infections cause 250,000 deaths and 3–5 million cases of severe illness during the average flu season. Severe influenza infections are associated with a combination of strong pro-inflammatory and weak anti-inflammatory immune respon
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications
Nature Communications
Type 1 regulatory T (Tr1) cells differentiate in response to signals engaging the T cell receptor (TCR), express high levels of the immunosuppressive cytokine IL-10, but not Foxp3, and can suppress inflammation and promote immune tolerance. Here we s
Autor:
Srikanth Battu, Gillipsie Minhas, Sumbul Afroz, Avery August, Shama, Nooruddin Khan, Weishan Huang, Sabrina Solouki, Jessica P. Elmore, Shaikh Matin
Publikováno v:
Sci Signal
Specific reduction in the intake of proteins or amino acids (AAs) offers enormous health benefits, including increased life span, protection against age-associated disorders, and improved metabolic fitness and immunity. Cells respond to conditions of
Autor:
Sabrina, Solouki, Weishan, Huang, Jessica, Elmore, Candice, Limper, Fei, Huang, Avery, August
Publikováno v:
J Immunol
CD8(+) T cells play a critical role in adaptive immunity, differentiating into CD8(+) memory T cells, which form the basis of protective cellular immunity. Vaccine efficacy is attributed to long-term protective immunity, and understanding the paramet
Publikováno v:
Pharmacol Ther
Autoimmune diseases are characterized by impaired immune tolerance towards self-antigens, leading to enhanced immunity to self by dysfunctional B cells and/or T cells. The activation of these cells is controlled by non-receptor tyrosine kinases (NRTK