Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sabrina Semmler"'
Autor:
Pranav, Garg, Sabrina, Semmler, Charlotte, Baudouin, Christine, Vande Velde, Steven S, Plotkin
Publikováno v:
Journal of Molecular Biology. 434:167697
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease primarily impacting motor neurons. Mutations in superoxide dismutase 1 (SOD1) are the second most common cause of familial ALS. Several of these mutations lead to misfolding or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2c1a2d1fe0aaf47b15d9f9bbd30e77
https://doi.org/10.1016/j.jmb.2022.167697
https://doi.org/10.1016/j.jmb.2022.167697
Autor:
Alexandra T. Star, Heidi M. McBride, Thomas M. Durcan, Elizabeth M. Meiering, Myriam Gagné, Janice Robertson, Christine Vande Velde, Jean-François Trempe, Sabrina Semmler, Neil R. Cashman, Pranav Garg, Elise Caron, Andrew N. Bayne, Nathalie Grandvaux, Steven S. Plotkin, Laurie Destroismaisons, Yousra Khalfallah, Sarah Pickles, Charlotte Baudouin, Mathilde Chaineau, Arsalan S. Haqqani, Emeline Hamon-Keromen
Publikováno v:
J Biol Chem
Amyotrophic lateral sclerosis (ALS) is a fatal disease, characterized by the selective loss of motor neurons leading to paralysis. Mutations in the gene encoding superoxide dismutase 1 (SOD1) are the second most common cause of familial ALS, and cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e140f4f50d7b9cd9106484395b1381a
https://nrc-publications.canada.ca/eng/view/object/?id=a04144de-e1cd-4b3e-a9fd-85a9f8650044
https://nrc-publications.canada.ca/eng/view/object/?id=a04144de-e1cd-4b3e-a9fd-85a9f8650044
Autor:
Steven S. Plotkin, Neil R. Cashman, Elise Caron, Laurie Destroismaisons, Alexandra T. Star, Mathilde Chaineau, Andrew N. Bayne, Charlotte Baudouin, Christine Vande Velde, Thomas M. Durcan, Yousra Khalfallah, Elizabeth M. Meiering, Heidi M. McBride, Myriam Gagné, Pranav Garg, Janice Robertson, Sabrina Semmler, Sarah Pickles, Arsalan S. Haqqani, Nathalie Grandvaux, Jean-François Trempe, Emeline Hamon-Keromen
Amyotrophic lateral sclerosis (ALS) is a fatal disease, characterized by the selective loss of motor neurons leading to paralysis. Mutations in the gene encoding superoxide dismutase1(SOD1) are the second most common cause of familial ALS, and consid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231767bf007cffe9a8e0311f65929bfb
Publikováno v:
Biophysical Journal. 120:297a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e90890624432b70862a54cdb12cc3a9e
https://doi.org/10.1016/j.bpj.2020.11.1897
https://doi.org/10.1016/j.bpj.2020.11.1897
Autor:
Hermona Soreq, Jade-Emmanuelle Deshaies, Benoit Chabot, Martine Tétreault, Sabrina Semmler, Christine Vande Velde, Lulzim Shkreta, Kathryn Volkening, Hadjara Sidibé, Michael J. Strong
Publikováno v:
Brain : a journal of neurology. 141(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bdc397014d8e94220b5632f339ae353
https://pubmed.ncbi.nlm.nih.gov/30364928
https://pubmed.ncbi.nlm.nih.gov/30364928
Autor:
Laurine Legroux, Helen R. Broom, Neil R. Cashman, Elizabeth M. Meiering, Sabrina Semmler, Laurie Destroismaisons, Christine Vande Velde, Sarah Pickles, Nathalie Arbour
Publikováno v:
Acta Neuropathologica Communications
Approximately 20 % of familial Amyotrophic Lateral Sclerosis (ALS) is caused by mutations in superoxide dismutase (SOD1), which leads to misfolding of the SOD1 protein, resulting in a toxic gain of function. Several conformation-restricted antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc0ac3dae3d1785e70a5060bbe1fa34
https://doi.org/10.1186/s40478-016-0313-8
https://doi.org/10.1186/s40478-016-0313-8