Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sabrina Sailer"'
Autor:
Sabrina Sailer-Frank, Silvia Annen
Publikováno v:
Zeitschrift für Hochschulentwicklung, Vol 18, Iss Sonderheft Planspiele (2023)
Spielerische Designs (z. B. Planspiele) gewinnen zunehmend an Beliebtheit, um Studierenden fachliche sowie soziale Kompetenzen zu vermitteln. Der vorliegende Beitrag befasst sich mit der Förderung von Kollaboration innerhalb des Formats Podiumsdisku
Externí odkaz:
https://doaj.org/article/8c7eedd6bcde43428eccc5102e6c20e3
Adaptations of the 3T3-L1 adipocyte lipidome to defective ether lipid catabolism upon Agmo knockdown
Autor:
Sabrina Sailer, Katharina Lackner, Mia L. Pras-Raves, Eric J.M. Wever, Jan B. van Klinken, Adriaan D. Dane, Stephan Geley, Jakob Koch, Georg Golderer, Gabriele Werner-Felmayer, Markus A. Keller, Werner Zwerschke, Frédéric M. Vaz, Ernst R. Werner, Katrin Watschinger
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 6, Pp 100222- (2022)
Little is known about the physiological role of alkylglycerol monooxygenase (AGMO), the only enzyme capable of cleaving the 1-O-alkyl ether bond of ether lipids. Expression and enzymatic activity of this enzyme can be detected in a variety of tissues
Externí odkaz:
https://doaj.org/article/2dea3320485f4a99830874c9c9ea55f9
Autor:
Sabrina Sailer, Stefan Coassin, Katharina Lackner, Caroline Fischer, Eileen McNeill, Gertraud Streiter, Christian Kremser, Manuel Maglione, Catherine M. Green, Daniela Moralli, Alexander R. Moschen, Markus A. Keller, Georg Golderer, Gabriele Werner-Felmayer, Irmgard Tegeder, Keith M. Channon, Benjamin Davies, Ernst R. Werner, Katrin Watschinger
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Background Genome editing in mice using either classical approaches like homologous recombination or CRISPR/Cas9 has been reported to harbor off target effects (insertion/deletion, frame shifts or gene segment duplications) that lead to muta
Externí odkaz:
https://doaj.org/article/8ea297638f64458d935a9b1e4923a4b5
Autor:
Gregor Oemer, Jakob Koch, Yvonne Wohlfarter, Mohammad T. Alam, Katharina Lackner, Sabrina Sailer, Lukas Neumann, Herbert H. Lindner, Katrin Watschinger, Markus Haltmeier, Ernst R. Werner, Johannes Zschocke, Markus A. Keller
Publikováno v:
Cell Reports, Vol 30, Iss 12, Pp 4281-4291.e4 (2020)
Summary: Cardiolipin (CL) is a phospholipid specific for mitochondrial membranes and crucial for many core tasks of this organelle. Its acyl chain configurations are tissue specific, functionally important, and generated via post-biosynthetic remodel
Externí odkaz:
https://doaj.org/article/9a23b0febb6b40339073e43e27937e3f
Autor:
Ernst R. Werner, Markus A. Keller, Sabrina Sailer, Daniele Seppi, Georg Golderer, Gabriele Werner-Felmayer, Raphael A. Zoeller, Katrin Watschinger
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 5, Pp 901-909 (2018)
Plasmanylethanolamine desaturase (PEDS) (EC 1.14.99.19) introduces the 1-prime double bond into plasmalogens, one of the most abundant phospholipids in the human body. This labile membrane enzyme has not been purified and its coding sequence is unkno
Externí odkaz:
https://doaj.org/article/8c400a8bd79746e7a7aab6e2083cfc92
Publikováno v:
Life, Vol 11, Iss 2, p 88 (2021)
The gene encoding alkylglycerol monooxygenase (AGMO) was assigned 10 years ago. So far, AGMO is the only known enzyme capable of catalysing the breakdown of alkylglycerols and lyso-alkylglycerophospholipids. With the knowledge of the genetic informat
Externí odkaz:
https://doaj.org/article/ea63f2a5216a415d9dd98a35f7959c48
Autor:
Yvonne Wohlfarter, Reiner Eidelpes, Ryan D. Yu, Sabrina Sailer, Jakob Koch, Daniela Karall, Sabine Scholl-Bürgi, Albert Amberger, Hauke S. Hillen, Johannes Zschocke, Markus A. Keller
Publikováno v:
Cellular and Molecular Life Sciences. 80
Autor:
Yvonne Wohlfarter, Reiner Eidelpes, Ryan D. Yu, Sabrina Sailer, Jakob Koch, Daniela Karall, Sabine Scholl-Bürgi, Albert Amberger, Hauke S. Hillen, Johannes Zschocke, Markus A. Keller
Publikováno v:
Cellular and Molecular Life Sciences
Multifunctional proteins are challenging as it can be difficult to confirm pathomechanisms associated with disease-causing genetic variants. The human 17β-hydroxysteroid dehydrogenase 10 (HSD10) is a moonlighting enzyme with at least two structurall
Autor:
Yvonne, Wohlfarter, Reiner, Eidelpes, Ryan D, Yu, Sabrina, Sailer, Jakob, Koch, Daniela, Karall, Sabine, Scholl-Bürgi, Albert, Amberger, Hauke S, Hillen, Johannes, Zschocke, Markus A, Keller
Publikováno v:
Cellular and molecular life sciences : CMLS. 79(11)
Multifunctional proteins are challenging as it can be difficult to confirm pathomechanisms associated with disease-causing genetic variants. The human 17β-hydroxysteroid dehydrogenase 10 (HSD10) is a moonlighting enzyme with at least two structurall
Autor:
Ernst R. Werner, Monica L. Fernández-Quintero, Nicolas Hulo, Georg Golderer, Sabrina Sailer, Katharina Lackner, Gabriele Werner-Felmayer, Klaus R. Liedl, Katrin Watschinger
Publikováno v:
Cellular and Molecular Life Sciences. 79
Plasmalogens are an abundant class of glycerophospholipids in the mammalian body, with special occurrence in the brain and in immune cell membranes. Plasmanylethanolamine desaturase (PEDS1) is the final enzyme of plasmalogen biosynthesis, which intro