Conformational Analysis of the Partially Disordered Measles Virus NTAIL-XD Complex by SDSL EPR Spectroscopy

Autor: Stéphanie Costanzo, Iztok Urbančič, Bruno Guigliarelli, Sabrina Rouger, Sandra Kure, Aleh Kavalenka, André Fournel, Janez Štrancar, Valérie Belle, Sonia Longhi

Publikováno v: Biophysical Journal
Biophysical Journal, Biophysical Society, 2010, 6 (98), pp.1055-1064
Biophysical Journal, 2010, 6 (98), pp.1055-1064

To characterize the structure of dynamic protein systems, such as partly disordered protein complexes, we propose a novel approach that relies on a combination of site-directed spin-labeled electron paramagnetic resonance spectroscopy and modeling of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f62abb5e9d3374d0c9663e8df3b35d0
https://doi.org/10.1016/j.bpj.2009.11.036

Mapping alpha-helical induced folding within the intrinsically disordered C-terminal domain of the measles virus nucleoprotein by site-directed spin-labeling EPR spectroscopy

Autor: André Fournel, Sonia Longhi, Stéphanie Costanzo, Janez Strancar, Sabrina Rouger, Elodie Liquière, Valérie Belle, Bruno Guigliarelli

Publikováno v: Proteins. 73(4)

Using site-directed spin-labeling EPR spectroscopy, we mapped the region of the intrinsically disordered C-terminal domain of measles virus nucleoprotein (NTAIL) that undergoes induced folding. In addition to four spin-labeled NTAIL variants (S407C,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309e0629d2c3a296d467aa1b23f4f4cb
https://pubmed.ncbi.nlm.nih.gov/18536007