Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sabrina Pobiega"'
Autor:
Florian Roisné-Hamelin, Sabrina Pobiega, Kévin Jézéquel, Simona Miron, Jordane Dépagne, Xavier Veaute, Didier Busso, Marie-Hélène Le Du, Isabelle Callebaut, Jean-Baptiste Charbonnier, Philippe Cuniasse, Sophie Zinn-Justin, Stéphane Marcand
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Different proteins localised at telomeres ensure chromosome end stability to prevent double strand-end break recognition. Here the authors provide new insight into how in S. cerevisiae the interaction between Rif2 and Rad50 inhibits MRX functions at
Externí odkaz:
https://doaj.org/article/26d231c1f074477282f58ddee8bde50e
Autor:
Jordane Dépagne, Xavier Veaute, Florian Roisné-Hamelin, Sophie Zinn-Justin, Stéphane Marcand, Sabrina Pobiega, Didier Busso, Marie-Hélène Le Du, Philippe Cuniasse, Jean-Baptiste Charbonnier, Simona Miron, Kévin Jézéquel, Isabelle Callebaut
Publikováno v:
Nature Communications
Nature Communications, 2021, 12 (1), pp.2763. ⟨10.1038/s41467-021-23035-w⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2763. ⟨10.1038/s41467-021-23035-w⟩
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, 2021, 12 (1), pp.2763. ⟨10.1038/s41467-021-23035-w⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2763. ⟨10.1038/s41467-021-23035-w⟩
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Specific proteins present at telomeres ensure chromosome end stability, in large part through unknown mechanisms. In this work, we address how the Saccharomyces cerevisiae ORC-related Rif2 protein protects telomere. We show that the small N-terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea365aff9a28535649b01f33e0d9ab1
https://hal.sorbonne-universite.fr/hal-03231067/document
https://hal.sorbonne-universite.fr/hal-03231067/document
Publikováno v:
Nucleic Acids Research
Chromosome fusions threaten genome integrity and promote cancer by engaging catastrophic mutational processes, namely chromosome breakage-fusion-bridge cycles and chromothripsis. Chromosome fusions are frequent in cells incurring telomere dysfunction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abfd089ebfa13fce8450bcf9241285f0
https://doi.org/10.1101/2021.05.04.442438
https://doi.org/10.1101/2021.05.04.442438
Autor:
Stéphane Marcand, Karine Dubrana, Masayuki Onishi, Sabrina Pobiega, Virginia Lopez, Natalja Barinova, John R. Pringle
Publikováno v:
Genes & Development. 29:322-336
Dicentric chromosomes are unstable products of erroneous DNA repair events that can lead to further genome rearrangements and extended gene copy number variations. During mitosis, they form anaphase bridges, resulting in chromosome breakage by an unk
Autor:
Stéphane Marcand, Sabrina Pobiega
Publikováno v:
Genes & Development. 24:720-733
Nonhomologous end-joining (NHEJ) inhibition at telomeres ensures that native chromosome ends do not fuse together. But the occurrence and consequences of rare telomere fusions are not well understood. It is notably unclear whether a telomere fusion c
Publikováno v:
EMBO Journal
EMBO Journal, 2013, 32, pp.805-815. ⟨10.1038/emboj.2013.24⟩
EMBO Journal, EMBO Press, 2013, 32, pp.805-815. ⟨10.1038/emboj.2013.24⟩
EMBO Journal, 2013, 32, pp.805-815. ⟨10.1038/emboj.2013.24⟩
EMBO Journal, EMBO Press, 2013, 32, pp.805-815. ⟨10.1038/emboj.2013.24⟩
International audience; In eukaryotes, permanent inhibition of the nonhomologous end joining (NHEJ) repair pathway at telomeres ensures that chromosome ends do not fuse. In budding yeast, binding of Rap1 to telomere repeats establishes NHEJ inhibitio