Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Sabrina Peter"'
Autor:
Jia Wei Siau, Asim Azhar Siddiqui, Sze Yi Lau, Srinivasaraghavan Kannan, Sabrina Peter, Yingying Zeng, Chandra Verma, Peter Droge, John F. Ghadessy
Publikováno v:
PLoS ONE, Vol 19, Iss 2 (2024)
Externí odkaz:
https://doaj.org/article/a8102e41f4cd4c198dc89e84d4769ffd
Autor:
Asim Azhar Siddiqui, Sabrina Peter, Eve Zi Xian Ngoh, Cheng-I. Wang, Shirelle Ng, John A. Dangerfield, Walter H. Gunzburg, Peter Dröge, Harshyaa Makhija
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Reliable cell-based platforms to test and/or produce biologics in a sustainable manner are important for the biotech industry. Utilizing enhanced λ integrase, a sequence-specific DNA recombinase, we developed a novel transgenesis platform involving
Externí odkaz:
https://doaj.org/article/7d08271bf26747a0830e808c29952bae
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0270173 (2022)
Seamless DNA vectors derived from bacterial plasmids are devoid of bacterial genetic elements and represent attractive alternatives for biomedical applications including DNA vaccines. Larger scale production of seamless vectors employs engineered Esc
Externí odkaz:
https://doaj.org/article/b600a7576a224fccab2d36a8041bba7e
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract HMGA2 belongs to the family of the high mobility group (HMG) proteins. It binds DNA via three AT-hook domains to the minor groove of adenine-thymine (AT) rich DNA. Recently, a new function of HMGA2 as a replication fork chaperone that protec
Externí odkaz:
https://doaj.org/article/9c95fdace04840abae38213a8de2e2ad
Autor:
Roland Ivanyi-Nagy, Syed Moiz Ahmed, Sabrina Peter, Priya Dharshana Ramani, Peh Fern Ong, Oliver Dreesen, Peter Dröge
Publikováno v:
eLife, Vol 7 (2018)
Telomerase RNA (TR) provides the template for DNA repeat synthesis at telomeres and is essential for genome stability in continuously dividing cells. We mapped the RNA interactome of human TR (hTR) and identified a set of non-coding and coding hTR-in
Externí odkaz:
https://doaj.org/article/e6ba360317084178b99a3b79b4b6f795
Autor:
Peh Fern Ong, Syed Moiz Ahmed, Priya Dharshana Ramani, Roland Ivanyi-Nagy, Oliver Dreesen, Sabrina Peter, Peter Dröge
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
Telomerase RNA (TR) provides the template for DNA repeat synthesis at telomeres and is essential for genome stability in continuously dividing cells. We mapped the RNA interactome of human TR (hTR) and identified a set of non-coding and coding hTR-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14071f06c85310291526f20568b5734a
http://hdl.handle.net/10220/47009
http://hdl.handle.net/10220/47009
Autor:
Sharon Chee, Shree Harsha Vijaya Chandra, Farid J. Ghadessy, Harshyaa Makhija, Peter Dröge, Cho Mar Myint Wai, Jia Wei Siau, Sabrina Peter
Publikováno v:
Protein Engineering, Design and Selection. 28:211-220
Advances in genome engineering are attendant on the development of novel enzyme variants with programed substrate specificities and improved activity. We have devised a novel selection method, wherein the activity of a recombinase deletes the gene en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ead20869fa5a5b6a9a6b0b5c5dea2b1
https://doi.org/10.1093/protein/gzv015
https://doi.org/10.1093/protein/gzv015
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
HMGA2 belongs to the family of the high mobility group (HMG) proteins. It binds DNA via three AT-hook domains to the minor groove of adenine-thymine (AT) rich DNA. Recently, a new function of HMGA2 as a replication fork chaperone that protects stem a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0383b3c4ead7aeb969d991107ba3c17f
https://hdl.handle.net/10356/88125
https://hdl.handle.net/10356/88125
Publikováno v:
Nucleic Acids Research
HMGA2 is an important chromatin factor that interacts with DNA via three AT-hook domains, thereby regulating chromatin architecture and transcription during embryonic and fetal development. The protein is absent from differentiated somatic cells, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095a6cfafbac7b280429a7cd0c1f78f3
http://hdl.handle.net/10220/45779
http://hdl.handle.net/10220/45779