Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sabrina N. Rahman"'
Autor:
Sabrina N. Rahman, Daniel A. McNaught-Flores, Yara Huppelschoten, Daniel da Costa Pereira, Arthur Christopoulos, Rob Leurs, Christopher J. Langmead
Publikováno v:
ACS Chemical Neuroscience, 14(4), 645-656. American Chemical Society
Rahman, S N, McNaught-Flores, D A, Huppelschoten, Y, da Costa Pereira, D, Christopoulos, A, Leurs, R & Langmead, C J 2023, ' Structural and Molecular Determinants for Isoform Bias at Human Histamine H 3 Receptor Isoforms ', ACS Chemical Neuroscience, vol. 14, no. 4, pp. 645-656 . https://doi.org/10.1021/acschemneuro.2c00425
Rahman, S N, McNaught-Flores, D A, Huppelschoten, Y, da Costa Pereira, D, Christopoulos, A, Leurs, R & Langmead, C J 2023, ' Structural and Molecular Determinants for Isoform Bias at Human Histamine H 3 Receptor Isoforms ', ACS Chemical Neuroscience, vol. 14, no. 4, pp. 645-656 . https://doi.org/10.1021/acschemneuro.2c00425
The human histamine H3 receptor (hH3R) is predominantly expressed in the CNS, where it regulates the synthesis and release of histamine and other neurotransmitters. Due to its neuromodulatory role, the hH3R has been associated with various CNS disord
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718f465c1b7d96c399b53e24acad288a
https://research.vu.nl/en/publications/c685e773-f7c9-4902-a64c-18c3df4fd827
https://research.vu.nl/en/publications/c685e773-f7c9-4902-a64c-18c3df4fd827
Autor:
Sabrina N. Rahman, Michael J. Robertson, Alpay B. Seven, Fadil M. Hannan, Jesper Mosolff Mathiesen, Ouliana Panova, Rajesh V. Thakker, Yang Gao, Georgios Skiniotis, Chensong Zhang, Hans Bräuner-Osborne, Justin G. Meyerowitz
Publikováno v:
Nature
Gao, Y, Robertson, M J, Rahman, S N, Seven, A B, Zhang, C, Meyerowitz, J G, Panova, O, Hannan, F M, Thakker, R V, Bräuner-Osborne, H, Mathiesen, J M & Skiniotis, G 2021, ' Asymmetric activation of the calcium-sensing receptor homodimer ', Nature, vol. 595, pp. 455-459 . https://doi.org/10.1038/s41586-021-03691-0
Gao, Y, Robertson, M J, Rahman, S N, Seven, A B, Zhang, C, Meyerowitz, J G, Panova, O, Hannan, F M, Thakker, R V, Bräuner-Osborne, H, Mathiesen, J M & Skiniotis, G 2021, ' Asymmetric activation of the calcium-sensing receptor homodimer ', Nature, vol. 595, pp. 455-459 . https://doi.org/10.1038/s41586-021-03691-0
The calcium-sensing receptor (CaSR), a cell-surface sensor for Ca2+, is the master regulator of calcium homeostasis in humans and is the target of calcimimetic drugs for the treatment of parathyroid disorders1. CaSR is a family C G-protein-coupled re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::693269c2b2519871c36c0a6e7ce0ec82
https://ora.ox.ac.uk/objects/uuid:6e7ae25a-1ba1-481e-9597-baf8358fcfc7
https://ora.ox.ac.uk/objects/uuid:6e7ae25a-1ba1-481e-9597-baf8358fcfc7
Label-Free Analysis with Multiple Parameters Separates G Protein-Coupled Receptor Signaling Pathways
Autor:
Sabrina N. Rahman, Dick J. van Iperen, Rob Leurs, Jeroen Kool, Teemu Suutari, Marjo Yliperttula, Arto Merivaara, Tapani Viitala, Henry F. Vischer
Publikováno v:
Analytical chemistry, 92(21), 14509-14516. American Chemical Society
Suutari, T, Rahman, S N, Vischer, H F, Van Iperen, D, Merivaara, A, Yliperttula, M, Leurs, R, Kool, J & Viitala, T 2020, ' Label-Free Analysis with Multiple Parameters Separates G Protein-Coupled Receptor Signaling Pathways ', Analytical chemistry, vol. 92, no. 21, pp. 14509-14516 . https://doi.org/10.1021/acs.analchem.0c02652
Suutari, T, Rahman, S N, Vischer, H F, Van Iperen, D, Merivaara, A, Yliperttula, M, Leurs, R, Kool, J & Viitala, T 2020, ' Label-Free Analysis with Multiple Parameters Separates G Protein-Coupled Receptor Signaling Pathways ', Analytical chemistry, vol. 92, no. 21, pp. 14509-14516 . https://doi.org/10.1021/acs.analchem.0c02652
Real-time label-free techniques are used to profile G protein-coupled receptor (GPCR) signaling pathways in living cells. However, interpreting the label-free signal responses is challenging, and previously reported methods do not reliably separate p