Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sabrina M. Huber"'
Autor:
Yang Jiang, Cécile Mingard, Sabrina M. Huber, Vakil Takhaveev, Maureen McKeague, Seiichiro Kizaki, Mirjam Schneider, Nathalie Ziegler, Vera Hürlimann, Julia Hoeng, Nicolas Sierro, Nikolai V. Ivanov, Shana J. Sturla
Publikováno v:
ACS Central Science, Vol 10, Iss 2, Pp 487-487 (2024)
Externí odkaz:
https://doaj.org/article/1d492b4c72f641b9b4fed67367b8adcb
Autor:
Daniel A. Rothenberg, J. Matthew Taliaferro, Sabrina M. Huber, Thomas J. Begley, Peter C. Dedon, Forest M. White
Publikováno v:
iScience, Vol 9, Iss , Pp 367-381 (2018)
Summary: To quantify dynamic protein synthesis rates, we developed MITNCAT, a method combining multiplexed isobaric mass tagging with pulsed SILAC (pSILAC) and bio-orthogonal non-canonical amino acid tagging (BONCAT) to label newly synthesized protei
Externí odkaz:
https://doaj.org/article/944a04c5a2954b2c94e120526e239a86
Publikováno v:
Toxics, Vol 7, Iss 1, p 17 (2019)
Living organisms respond to environmental changes and xenobiotic exposures by regulating gene expression. While heat shock, unfolded protein, and DNA damage stress responses are well-studied at the levels of the transcriptome and proteome, tRNA-media
Externí odkaz:
https://doaj.org/article/8e313cdad0a3457b89ee77cb6df667ae
Autor:
Sabrina M. Huber, Ulrike Begley, Anwesha Sarkar, William Gasperi, Evan T. Davis, Vasudha Surampudi, May Lee, J. Andres Melendez, Peter C. Dedon, Thomas J. Begley
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 119 (38)
Cells respond to environmental stress by regulating gene expression at the level of both transcription and translation. The similar to 50 modified ribonucleotides of the human epitranscriptome contribute to the latter, with mounting evidence that dyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163fe2d88dbfa82ae88a9b567510d539
https://pubmed.ncbi.nlm.nih.gov/36095201
https://pubmed.ncbi.nlm.nih.gov/36095201
Autor:
Yang Jiang, Cécile Mingard, Sabrina M. Huber, Vakil Takhaveev, Maureen McKeague, Seiichiro Kizaki, Mirjam Schneider, Nathalie Ziegler, Vera Hürlimann, Julia Hoeng, Nicolas Sierro, Nikolai V. Ivanov, Shana J. Sturla
Publikováno v:
ACS Central Science, 9 (3)
Chemical modifications to DNA bases, including DNA adducts arising from reactions with electrophilic chemicals, are well-known to impact cell growth, miscode during replication, and influence disease etiology. However, knowledge of how genomic sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de5c945859089740f0c7f9bcedc5db96
Autor:
Sabrina M. Huber, Claudia M. N. Aloisi, Susanne M Geisen, Shana J. Sturla, Nora A Escher, Emma S Sandell
Publikováno v:
Chemical Research in Toxicology, 34 (6)
The O6-alkylguanosine adduct O6-carboxymethyldeoxyguanosine (O6-CMdG) has been detected at elevated levels in blood and tissue samples from colorectal cancer patients and from healthy volunteers after consuming red meat. The diazo compound l-azaserin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c182f32d117a391f628962532041bb
https://doi.org/10.1021/acs.chemrestox.0c00471
https://doi.org/10.1021/acs.chemrestox.0c00471
Autor:
Michael S. DeMott, Daniel Yim, Sabrina M. Huber, Duanduan Ma, Jo Marie Bacusmo, Peter C. Dedon, Bo Cao, Jennifer Hu, Jieliang Zhou, Sidney Vermeulen, Thomas J. Begley, Valérie de Crécy-Lagard, Nick Davis, Stuart S. Levine
Publikováno v:
Nature biotechnology
Current next-generation RNA-sequencing (RNA-seq) methods do not provide accurate quantification of small RNAs within a sample, due to sequence-dependent biases in capture, ligation and amplification during library preparation. We present a method, ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b6fb9afeeb2882c471145b651bf46e
https://doi.org/10.1038/s41587-021-00874-y
https://doi.org/10.1038/s41587-021-00874-y
Autor:
Susanne M, Geisen, Claudia M N, Aloisi, Sabrina M, Huber, Emma S, Sandell, Nora A, Escher, Shana J, Sturla
Publikováno v:
Chemical research in toxicology. 34(6)
The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93d374941577fdb037d69cd4a48ff8dc
https://pubmed.ncbi.nlm.nih.gov/34061515
https://pubmed.ncbi.nlm.nih.gov/34061515
Publikováno v:
Chemical Research in Toxicology. 33:283-285
Damage to DNA is a central mechanism to the initiation of carcinogenesis. As a consequence, precise DNA damage detection is essential for an effective risk assessment of xenobiotics and constitutes a powerful tool for human biomonitoring and early st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d8659f5fab88d3beb58a0441f4fbb4
https://doi.org/10.1021/acs.chemrestox.9b00369
https://doi.org/10.1021/acs.chemrestox.9b00369
Autor:
Ulrike Begley, William Gasperi, Thomas J. Begley, Sabrina M. Huber, Peter C. Dedon, Anwesha Sarkar, Steven Nevins
Publikováno v:
Wiley interdisciplinary reviews. RNAFURTHER READINGREFERENCES. 12(6)
RNA modifications and their corresponding epitranscriptomic writer and eraser enzymes regulate gene expression. Altered RNA modification levels, dysregulated writers, and sequence changes that disrupt epitranscriptomic marks have been linked to mitoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9814bf26857a91244e7c5d63e52bbfbd
https://pubmed.ncbi.nlm.nih.gov/33987958
https://pubmed.ncbi.nlm.nih.gov/33987958