Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sabrina Lizot"'
Autor:
Arianna Moiani, Gil Letort, Sabrina Lizot, Anne Chalumeau, Chloe Foray, Tristan Felix, Diane Le Clerre, Sonal Temburni-Blake, Patrick Hong, Sophie Leduc, Noemie Pinard, Alan Marechal, Eduardo Seclen, Alex Boyne, Louisa Mayer, Robert Hong, Sylvain Pulicani, Roman Galetto, Agnès Gouble, Marina Cavazzana, Alexandre Juillerat, Annarita Miccio, Aymeric Duclert, Philippe Duchateau, Julien Valton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Sickle cell disease is a devastating blood disorder that originates from a single point mutation in the HBB gene coding for hemoglobin. Here, we develop a GMP-compatible TALEN-mediated gene editing process enabling efficient HBB correction v
Externí odkaz:
https://doaj.org/article/a5ed07ba92514c729d823ca1c6aa5120
Autor:
Soëli Charbonnier, Sabrina Lizot, Isabelle André, Emmanuelle Six, Christophe Benoist, Roman Klifa, Steicy Sobrino, Juliette Leon, Juliette Olivré, Armance Marchal, David A. Gross, Hélène Vinçon, Baptiste Lamarthée, Julien Zuber, Alexandrine Garrigue, Marina Cavazzana, Marianne Delville, Mario Amendola, Romane Thouenon, Chantal Lagresle-Peyrou, Florence Bellier, Axel Schambach
Publikováno v:
Blood
Blood, 2021, 137 (17), pp.2326-2336. ⟨10.1182/blood.2020009187⟩
Blood, American Society of Hematology, 2021, 137 (17), pp.2326-2336. ⟨10.1182/blood.2020009187⟩
Blood, 2021, 137 (17), pp.2326-2336. ⟨10.1182/blood.2020009187⟩
Blood, American Society of Hematology, 2021, 137 (17), pp.2326-2336. ⟨10.1182/blood.2020009187⟩
Immunodysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is caused by mutations in forkhead box P3 (FOXP3), which lead to the loss of function of regulatory T cells (Tregs) and the development of autoimmune manifestations early
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c739ca1788645c49f32869d91d4b656
https://hal.science/hal-03588460
https://hal.science/hal-03588460
Autor:
Gil Letort, Sophie Leduc, Mathilde Dusseaux, Tristan Felix, Agnès Gouble, Carrie Brownstein, Louisa Mayer, Cecile Shiffer-Mannoui, Philippe Duchateau, Aymeric Duclert, Selena Kazancioglu, Patrick Hong, Sara Nik, Alex Boyne, Sabrina Lizot, Chloe Foray, Annarita Miccio, Noemie Pinard, Alexa Chirinos, Mark G. Frattini, Anne Chalumeau, Alexandre Juillerat, Giacomo Frati, Arianna Moiani, Sonal Temburni-Blake, Julien Valton
Publikováno v:
Blood. 138:1856-1856
Sickle cell disease (SCD) is one of the most common inherited diseases affecting millions of people worldwide. SCD stems from a single point mutation (A>T) in exon 1 of the HBB gene which results in sickle hemoglobin. The only available curative trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ca9d1d3185140c4d53b6bb95b8b4273
https://doi.org/10.1182/blood-2021-153549
https://doi.org/10.1182/blood-2021-153549