Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sabrina Kueckelmann"'
Autor:
Volker Boehm, Sabrina Kueckelmann, Jennifer V. Gerbracht, Sebastian Kallabis, Thiago Britto-Borges, Janine Altmüller, Marcus Krüger, Christoph Dieterich, Niels H. Gehring
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Degradation of nonsense mediated mRNA decay (NMD) substrates is carried out by two seemingly independent pathways, SMG6-mediated endonucleolytic cleavage and/or SMG5-SMG7-induced accelerated deadenylation. Here the authors show that SMG5-SMG7 maintai
Externí odkaz:
https://doaj.org/article/9c2915beac40413f8c56308a467df541
Autor:
Christoph Dieterich, Volker Boehm, Damaris Wallmeroth, Sabrina Kueckelmann, Janine Altmüller, Niels Gehring, Jan-Wilm Lackmann
Publikováno v:
The EMBO journal. 41(10)
The paralogous human proteins UPF3A and UPF3B are involved in recognizing mRNAs targeted by nonsense-mediated mRNA decay (NMD). UPF3B has been demonstrated to support NMD, presumably by bridging an exon junction complex (EJC) to the NMD factor UPF2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c336a7ae249a7b0974d435eb91f57b7
https://pubmed.ncbi.nlm.nih.gov/35451084
https://pubmed.ncbi.nlm.nih.gov/35451084
Autor:
Sebastian Kallabis, Thiago Britto-Borges, Niels H. Gehring, Christoph Dieterich, Jennifer V. Gerbracht, Sabrina Kueckelmann, Marcus Krüger, Volker Boehm, Janine Altmüller
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Eukaryotic gene expression is constantly controlled by the translation-coupled nonsense-mediated mRNA decay (NMD) pathway. Aberrant translation termination leads to NMD activation, resulting in phosphorylation of the central NMD factor UPF1 and robus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335eb809dbf1c462a750bdef9c2f47a7
https://pubmed.ncbi.nlm.nih.gov/34172724
https://pubmed.ncbi.nlm.nih.gov/34172724
Autor:
Christoph Dieterich, Volker Boehm, Niels H. Gehring, Janine Altmueller, Sabrina Kueckelmann, Thiago Britto-Borges, Jennifer V. Gerbracht
Eukaryotic gene expression is constantly regulated and controlled by the translation-coupled nonsense-mediated mRNA decay (NMD) pathway. Aberrant translation termination leads to NMD activation and robust clearance of NMD targets via two seemingly in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14dc216151fdd86cb7372470c09cc482
https://doi.org/10.1101/2020.07.07.191437
https://doi.org/10.1101/2020.07.07.191437
