Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sabrina Hübschmann"'
Autor:
Senthilvelrajan Kaniyappan, Katharina Tepper, Jacek Biernat, Ram Reddy Chandupatla, Sabrina Hübschmann, Stephan Irsen, Sandra Bicher, Christoph Klatt, Eva-Maria Mandelkow, Eckhard Mandelkow
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-16 (2020)
Abstract Tau aggregation into amyloid fibers based on the cross-beta structure is a hallmark of several Tauopathies, including Alzheimer Disease (AD). Trans-cellular propagation of Tau with pathological conformation has been suggested as a key diseas
Externí odkaz:
https://doaj.org/article/bfd9cd7b197b44c1a1811c99b7845f75
Autor:
Sabrina Hübschmann, Katharina Tepper, Ram Reddy Chandupatla, Senthilvelrajan Kaniyappan, Sandra Bicher, Jacek Biernat, Eva-Maria Mandelkow, Christoph Klatt, Stephan Irsen, Eckhard Mandelkow
Publikováno v:
Molecular neurodegeneration
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-16 (2020)
Molecular neurodegeneration 15(1), 39 (2020). doi:10.1186/s13024-020-00389-1
Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-16 (2020)
Molecular neurodegeneration 15(1), 39 (2020). doi:10.1186/s13024-020-00389-1
Molecular Neurodegeneration
Tau aggregation into amyloid fibers based on the cross-beta structure is a hallmark of several Tauopathies, including Alzheimer Disease (AD). Trans-cellular propagation of Tau with pathological conformation has been suggested as a key disease mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51342de34fe195e12ac8483d5d3ebddc
https://hdl.handle.net/21.11116/0000-0006-D0B8-F21.11116/0000-0006-D0BA-D
https://hdl.handle.net/21.11116/0000-0006-D0B8-F21.11116/0000-0006-D0BA-D
Autor:
Frank J.A. Dennissen, Eva-Maria Mandelkow, Eckhard Mandelkow, Marcus Pickhardt, Annukka Aho, Sabrina Hübschmann, Thomas Timm, Jacek Biernat
Publikováno v:
Neurobiology of Aging
Neurobiology of aging 57, 47-63 (2017). doi:10.1016/j.neurobiolaging.2017.04.022
Neurobiology of aging 57, 47-63 (2017). doi:10.1016/j.neurobiolaging.2017.04.022
The aggregation of Tau protein is a hallmark of neurodegenerative diseases including Alzheimer's disease. Previously, we generated a cell model of tauopathy based on the 4-repeat domain with the FTDP-17 mutation ΔK280 (Tau4RDΔK) which is expressed
Autor:
Sabrina Hübschmann, Eckhard Mandelkow, Susanne Wegmann, Daniel J. Müller, Jacek Biernat, Katharina Tepper, Lars Redecke, Eva-Maria Mandelkow, Thomas Timm, Satish Kumar
Publikováno v:
The Journal of biological chemistry
Journal of Biological Chemistry, 289 (49)
The journal of biological chemistry 289(49), 34389-34407 (2014). doi:10.1074/jbc.M114.611368
The Journal of Biological Chemistry
Journal of Biological Chemistry, 289 (49)
The journal of biological chemistry 289(49), 34389-34407 (2014). doi:10.1074/jbc.M114.611368
The Journal of Biological Chemistry
Abnormal phosphorylation (“hyperphosphorylation”) and aggregation of Tau protein are hallmarks of Alzheimer disease and other tauopathies, but their causative connection is still a matter of debate. Tau with Alzheimer-like phosphorylation is also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed5aa4ec06188e07b794ebd3cd3d149