Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sabrina Genssler"'
Autor:
Markus Haake, Beatrice Haack, Tina Schäfer, Patrick N. Harter, Greta Mattavelli, Patrick Eiring, Neha Vashist, Florian Wedekink, Sabrina Genssler, Birgitt Fischer, Julia Dahlhoff, Fatemeh Mokhtari, Anastasia Kuzkina, Marij J. P. Welters, Tamara M. Benz, Lena Sorger, Vincent Thiemann, Giovanni Almanzar, Martina Selle, Klara Thein, Jacob Späth, Maria Cecilia Gonzalez, Carmen Reitinger, Andrea Ipsen-Escobedo, Kilian Wistuba-Hamprecht, Kristin Eichler, Katharina Filipski, Pia S. Zeiner, Rudi Beschorner, Renske Goedemans, Falk Hagen Gogolla, Hubert Hackl, Rogier W. Rooswinkel, Alexander Thiem, Paula Romer Roche, Hemant Joshi, Dirk Pühringer, Achim Wöckel, Joachim E. Diessner, Manfred Rüdiger, Eugen Leo, Phil F. Cheng, Mitchell P. Levesque, Matthias Goebeler, Markus Sauer, Falk Nimmerjahn, Christine Schuberth-Wagner, Stefanie von Felten, Michel Mittelbronn, Matthias Mehling, Andreas Beilhack, Sjoerd H. van der Burg, Angela Riedel, Benjamin Weide, Reinhard Dummer, Jörg Wischhusen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Immune checkpoint blockade therapy is beneficial and even curative for some cancer patients. However, the majority don’t respond to immune therapy. Across different tumor types, pre-existing T cell infiltrates predict response to checkpoin
Externí odkaz:
https://doaj.org/article/5207814fce1e426b9e431dafa4d554e4
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/0cb089bdd9004b11ba61518e9d78403f
Autor:
Sabrina Genßler, Eugen Leo, Christine Schuberth-Wagner, Markus Haake, Neha Vashist, Beatrice Haack, Birgitt Fischer, Kristin Eichler, Matthias Kist, Joerg Wischhusen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/27a514e056894717a9a56526816cca58
Autor:
Markus Haake, Beatrice Haack, Sabrina Genßler, Julia Weigandt, Marlene Auer, Vincent Thiemann, Wahid M. Haq, Melanie Haag, Florian Wedekink, Birgitt Fischer, Kathrin Klar, Matthias Wölfl, Christine Schuberth-Wagner, Jorg Wischhusen
Publikováno v:
Cancer Research. 82:6118-6118
Background: Growth and differentiation factor 15 (GDF-15), a divergent member of the TGF-β protein superfamily, shows low physiological baseline expression. GDF-15 is, however, strongly upregulated during pregnancy. It is further induced in stressed
Autor:
Kilian Wistuba-Hamprecht, Eugen Leo, Mitchell P. Levesque, Tina Schäfer, Sabrina Genßler, Markus Haake, Reinhard Dummer, Birgitt Fischer, Jörg Wischhusen, Neha Vashist, Falk Nimmerjahn, Phil F. Cheng, Christine Schuberth-Wagner, Alexander Martens, Beatrice Haack, Kathrin Klar, Benjamin Weide, Michel Mittelbronn, Florian Wedekink, Patrick N. Harter
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A597-A597
BackgroundImmune checkpoint blockade (ICB) can achieve durable responses in a subgroup of patients with metastatic cancer, only. Poor immune effector cell infiltration into the tumor microenvironment is a major obstacle to successful therapy. Growth
Autor:
J Wischhusen, Mitchell P. Levesque, Falk Nimmerjahn, Sjoerd H. van der Burg, Kilian Wistuba-Hamprecht, Benjamin Weide, Reinhard Dummer, Marij J. P. Welters, Christine Schuberth-Wagner, Manfred Ruediger, Patrick N. Harter, Michel Mittelbronn, Sabrina Genßler, Alexander Martens, Neha Vashist, Markus Haake, Eugen Leo
Publikováno v:
Journal of Clinical Oncology. 39:e14532-e14532
e14532 Background: Growth and differentiation factor 15 (GDF-15) is a divergent member of the TGF-β superfamily with low to absent expression in healthy tissue. GDF-15 has been linked to feto-maternal immune tolerance, to prevention of excessive imm
Autor:
Oliver G. Ottmann, Sabrina Genßler, Heike Pfeifer, Ralf Schubert, Peter Bader, Miriam E. Friede, Verena Pfirrmann, Sarah Oelsner, Christian J. Buchholz, Winfried S. Wels, Eva Rettinger, Juliane Wagner, Evelyn Ullrich
Publikováno v:
International Journal of Cancer. 139:1799-1809
Pre-emptive cancer immunotherapy by donor lymphocyte infusion (DLI) using cytokine-induced killer (CIK) cells may be beneficial to prevent relapse with a reduced risk of causing graft-versus-host-disease. CIK cells are a heterogeneous effector cell p
Autor:
Eugen Leo, Neha Vashist, Markus Haake, Jörg Wischhusen, Paula S. Römer, Sabrina Genssler, Falk Nimmerjahn, Jessica Kammer, Birgitt Fischer, Kristin H. Eichler, Manfred Rudiger, Christine Schuberth-Wagner
Publikováno v:
Cancer Research. 80:5597-5597
Background: Growth and differentiation factor 15 (GDF-15) is a remote member of the TGF-β protein family with low to absent expression in healthy tissue. During pregnancy GDF-15 is secreted in high amounts by placenta contributing to feto-maternal t
Autor:
Winfried S. Wels, Cord Hartmann, Manuel Grez, Sabrina Genßler, Nina Müller, Joachim Koch, Andrea Kinner
Publikováno v:
International Journal of Cancer. 134:2547-2559
Epidermal growth factor receptor (EGFR) plays an important role in essential cellular processes such as proliferation, survival and migration. Aberrant activation of EGFR is frequently found in human cancers of various origins and has been implicated
Autor:
Sarah, Oelsner, Juliane, Wagner, Miriam E, Friede, Verena, Pfirrmann, Sabrina, Genßler, Eva, Rettinger, Christian J, Buchholz, Heike, Pfeifer, Ralf, Schubert, Oliver G, Ottmann, Evelyn, Ullrich, Peter, Bader, Winfried S, Wels
Publikováno v:
International journal of cancer. 139(8)
Pre-emptive cancer immunotherapy by donor lymphocyte infusion (DLI) using cytokine-induced killer (CIK) cells may be beneficial to prevent relapse with a reduced risk of causing graft-versus-host-disease. CIK cells are a heterogeneous effector cell p