Výsledky vyhledávání - "Sabrina Farrokh"

Akademický článek

Extra-Nuclear Functions of the Transcription Factor Grainyhead-Like 3 in the Endothelium—Interaction with Endothelial Nitric Oxide Synthase

Autor: Kirsten Jander, Jan Greulich, Stefanie Gonnissen, Niloofar Ale-Agha, Christine Goy, Philipp Jakobs, Sabrina Farrokh, Corina Marziano, Swapnil K. Sonkusare, Judith Haendeler, Joachim Altschmied

Publikováno v: Antioxidants, Vol 10, Iss 3, p 428 (2021)

We previously demonstrated that the transcription factor Grainyhead-like 3 (GRHL3) has essential functions in endothelial cells by inhibiting apoptosis and promoting migration as well as activation of endothelial nitric oxide synthase (eNOS). We now

Externí odkaz: https://doaj.org/article/cacda6784fe64f48b1f84bf0b3dd054e

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Extra-Nuclear Functions of the Transcription Factor Grainyhead-Like 3 in the Endothelium—Interaction with Endothelial Nitric Oxide Synthase

Autor: Stefanie Gonnissen, Kirsten Jander, Niloofar Ale-Agha, Swapnil K. Sonkusare, Christine Goy, Judith Haendeler, Joachim Altschmied, Corina Marziano, Jan Greulich, Sabrina Farrokh, Philipp Jakobs

Publikováno v: Antioxidants
Volume 10
Issue 3
Antioxidants, Vol 10, Iss 428, p 428 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::668f5233b91eb59f2fd06e1c0fcd5a74

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Critical Regulators of Endothelial Cell Functions: For a Change Being Alternative

Autor: Judith Haendeler, Heiner Schaal, Anna-Lena Brillen, Joachim Altschmied, Sabrina Farrokh

Publikováno v: Antioxidants & Redox Signaling. 22:1212-1229

The endothelium regulates vessel dilation and constriction, balances hemostasis, and inhibits thrombosis. In addition, pro- and anti-angiogenic molecules orchestrate proliferation, survival, and migration of endothelial cells. Regulation of all these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf59c9e57606d653efc554faf1ebb4c
https://doi.org/10.1089/ars.2014.6023

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Fetal gender and gestational age differentially affect PCSK9 levels in intrauterine growth restriction

Autor: Werner Rath, Andre Farrokh, Bartlomiej Berger, Ulrich Pecks, Imke Lueg, Christel Eckmann-Scholz, Nicolai Maass, Sabrina Farrokh

Publikováno v: Lipids in Health and Disease
Lipids in health and disease 15(1), 193 (2016). doi:10.1186/s12944-016-0365-6

Lipids in health and disease 15(1), 193 (2016). doi:10.1186/s12944-016-0365-6
Published by Biomed Central, London

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e264b461236eb063e54198b728a798

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Abstract 234: Defining Domains In The Transcription Factor Grainyhead-like 3 Required For Protective Functions In The Endothelium

Autor: Sabrina Farrokh, Niloofar Ale-Agha, Judith Haendeler, Joachim Altschmied

Publikováno v: Circulation Research. 113

Important aspects during aging of human endothelial cells (EC) are an increased apoptosis level and a reduced migratory capacity. In a screening for anti-apoptotic genes we have identified the transcription factor Grainyhead-like 3 (GRHL3) and demons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b959f4c88d5c44d9bbf55c9b9bbefb37
https://doi.org/10.1161/res.113.suppl_1.a234

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Abstract 267: Opposing Functions of Two Splice Variants of the Human Transcription Factor Grainyhead-like 3 in Endothelial Cells And in vivo

Autor: Joachim Altschmied, Nicole Büchner, Sascha Jakob, Sabrina Farrokh, Christine Goy, Heiner Schaal, Judith Haendeler

Publikováno v: Circulation Research. 113

Grainyhead-like 3 (GRHL3) is a member of the evolutionary conserved Grainyhead family of transcription factors. In humans, three isoforms are derived from differential first exon usage and alternative splicing, which differ only in their N-terminus.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bdce49a1cee326ba58f591d021290dc8
https://doi.org/10.1161/res.113.suppl_1.a267

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Two isoforms of Sister-Of-Mammalian Grainyhead have opposing functions in endothelial cells and in vivo

Autor: Martin Graf, Miriam M. Cortese-Krott, Christopher Guettler, Kerstin Kunze, Karl Köhrer, Judith Haendeler, Nicole Büchner, Margarete Lukosz, Sascha Jakob, Arne Mlynek, René Deenen, Francisca Guardiola-Serrano, Christine Goy, Christoph Winkler, Heiner Schaal, Joachim Altschmied, Sabrina Farrokh

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology. 33(7)

Objective— Sister-of-Mammalian Grainyhead (SOM) is a member of the Grainyhead family of transcription factors. In humans, 3 isoforms are derived from differential first exon usage and alternative splicing and differ only in their N terminal domain.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc7b23891a86ecac52c5f99a1561d5f
https://pubmed.ncbi.nlm.nih.gov/23685552

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