Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Sabrina Falcinelli"'
1
Concomitant activation of Wnt pathway and loss of mismatch repair function in human melanoma
Autor: Elena Pagani, Silvia Bernardini, Naomi De Luca, Enzo Bonmassar, Sabrina Falcinelli, Alberto Pacchiarotti, Giovanna Zambruno, Ester Alvino, Daniele Castiglia, Stefania D'Atri
Publikováno v: Genes, Chromosomes and Cancer. 47:614-624
Constitutive activation of the Wnt pathway plays a key role in the development of colorectal cancer and has also been implicated in the pathogenesis of other malignancies. Deregulation of Wnt signaling mainly occurs through genetic alterations of APC
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451ba9fa4928caec23b4617e9fdc6c86
https://doi.org/10.1002/gcc.20567
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2
hMSH3 overexpression and cellular response to cytotoxic anticancer agents
Autor: Grazia Graziani, Elena Pagani, Lauretta Levati, Josef Jiricny, Sabrina Falcinelli, Rita Pepponi, Enzo Bonmassar, Pedro Miguel Lacal, Patrizia Vernole, Stefania D'Atri
Publikováno v: Scopus-Elsevier
Carcinogenesis (N.Y., Print) 22 (2001): 1131–1137.
info:cnr-pdr/source/autori:Pepponi R., Graziani G., Falcinelli S., Vernole P., Levati L., Lacal P.M., Pagani E., Bonmassar E., Jiricny J., D?Atri S./titolo:hMSH3 overexpression and cellular response to cytotoxic anticancer agents./doi:/rivista:Carcinogenesis (N.Y., Print)/anno:2001/pagina_da:1131/pagina_a:1137/intervallo_pagine:1131–1137/volume:22
Mutations or transcriptional silencing of mismatch repair genes have been linked with tumour cell resistance to O(6)-guanine methylating agents, 6-thioguanine, cisplatin, doxorubicin and etoposide. Recently, it has been demonstrated that overexpressi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1186df0bec22d748569f10e791466e96
https://doi.org/10.1093/carcin/22.8.1131
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3
Human Melanoma Cells Secrete and Respond to Placenta Growth Factor and Vascular Endothelial Growth Factor
Autor: Teresa Odorisio, Sabrina Falcinelli, Cristina Maria Failla, Cataldo Schietroma, Pedro Miguel Lacal, Giovanna Zambruno, Stefania D'Atri, Elena Pagani
Publikováno v: Journal of Investigative Dermatology. 115:1000-1007
The vascular endothelial growth factor is produced by a large variety of human tumors, including melanoma, in which it appears to play an important role in the process of tumor-induced angiogenesis. Little information is available on the role of plac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e490a334461dc94ab5b4b82ce27479
https://doi.org/10.1046/j.1523-1747.2000.00199.x
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4
Combined effect of temozolomide and hyperthermia on human melanoma cell growth and O6-methylguanine-DNA methyltransferase activity
Autor: Elena, Pagani, Sabrina, Falcinelli, Rita, Pepponi, Mario, Turriziani, Patrizia, Caporaso, Simona, Caporali, Enzo, Bonmassar, Stefania, D'Atri
Publikováno v: International journal of oncology. 30(2)
Hyperthermic isolated limb perfusion (HILP) with L-phenylalanine mustard (L-PAM) represents an effective treatment for locally advanced melanoma of the limbs. However, regional chemotherapy of melanoma still needs to be improved. Temozolomide (TMZ) i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4ad3da210ea61c84f03385e5bce2b472
https://pubmed.ncbi.nlm.nih.gov/17203227
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5
DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system
Autor: Simona, Caporali, Sabrina, Falcinelli, Giuseppe, Starace, Maria Teresa, Russo, Enzo, Bonmassar, Josef, Jiricny, Stefania, D'Atri
Publikováno v: Molecular pharmacology. 66(3)
The mammalian mismatch repair (MMR) system has been implicated in activation of the G(2) checkpoint induced by methylating agents. In an attempt to identify the signaling events accompanying this phenomenon, we studied the response of MMR-proficient
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f7042249d1bc4cf189581e4dda0c937e
https://pubmed.ncbi.nlm.nih.gov/15322239
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6
Expression and characterization of Pseudomonas aeruginosa cytochrome c-551 and two site-directed mutants: Role of tryptophan 56 in the modulation of redox properties
Autor: Maria Chiara Silvestrini, Sabrina Falcinelli, Marzia Arese, Gabriella Rolli, Elisabetta Zennaro, Graziella Ranghino, Francesca Cutruzzolà, Andrea Anselmino, Ilaria Ciabatti
Publikováno v: Scopus-Elsevier
The gene coding for Pseudomonas aeruginosacytochrome c-551 was expressed in Pseudomonas putidaunder aerobic conditions, using two different expression vectors; the more efficient proved to be pNM185, induced by m-toluate. Mature holo-(cytochrome c-55
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dde638be016eaded824ecc033f9da8a
http://hdl.handle.net/11573/256892
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8
High-Frequency Microsatellite Instability is Associated with Defective DNA Mismatch Repair in Human Melanoma
Autor: Josef Jiricny, Stefania D'Atri, Ester Alvino, Giancarlo Marra, Rita Pepponi, Giulio Ferranti, Claudia Perrera, Daniele Castiglia, Ritva Haider, Enzo Bonmassar, Giovanna Zambruno, Sabrina Falcinelli, Elena Pagani
Publikováno v: Journal of Investigative Dermatology. (1):79-86
Hereditary nonpolyposis colorectal cancers and a steadily increasing number of sporadic tumors display microsatellite instability. In colorectal tumors, high-frequency microsatellite instability is strictly associated with inactivation of the DNA mis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6112ee6895fd9e6782d0fe3e2936d0d3
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9
DNA repair enzymes and cytotoxic effects of temozolomide: Comparative studies between tumor cells and normal cells of the immune system
Autor: Francesca Passarelli, Ester Alvino, Sabrina Falcinelli, Stefania D'Atri, Laura Bonmassar, P Lacal, Mario Turriziani, Maria Pia Fuggetta, Elena Pagani, S.P. Prete, Rita Pepponi, F. Guadagni
Publikováno v: Scopus-Elsevier
O6-alkylguanine-DNA alkyltransferase (OGAT) and the mismatch repair system (MRS) play a crucial role in the susceptibility of tumor cells to the cytotoxic effects of agents that generate O6-methylguanine in DNA, including the triazene compound temozo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65b406157790b6d567a009ca1a32043
http://www.scopus.com/inward/record.url?eid=2-s2.0-0038627968&partnerID=MN8TOARS
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