Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sabrina Dusi"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Joseph et al. reveal that monoSUMOylated DDK kinase, implicated in replication initiation, acts with Rad51 recombinase to prevent replication fork uncoupling and to mediate recombination-dependent gap-filling in the presence of genotoxic stress.
Externí odkaz:
https://doaj.org/article/f7f07656808e4b479bc8dbab1e69ac60
Autor:
Takuya Abe, Ryotaro Kawasumi, Michele Giannattasio, Sabrina Dusi, Yui Yoshimoto, Keiji Miyata, Koyuki Umemura, Kouji Hirota, Dana Branzei
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
AND-1, the vertebrate orthologue of Ctf4, is a critical player during DNA replication and for maintenance of genome integrity. Here the authors use a conditional AND-1 depletion system in avian DT40 cells to reveal the consequences of the lack of AND
Externí odkaz:
https://doaj.org/article/16bdca11b36a40e69c41022d7bb4774d
Autor:
Daniel I Orellana, Paolo Santambrogio, Alicia Rubio, Latefa Yekhlef, Cinzia Cancellieri, Sabrina Dusi, Serena G Giannelli, Paola Venco, Pietro G Mazzara, Anna Cozzi, Maurizio Ferrari, Barbara Garavaglia, Stefano Taverna, Valeria Tiranti, Vania Broccoli, Sonia Levi
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 10, Pp 1197-1211 (2016)
Abstract Pantothenate kinase‐associated neurodegeneration (PKAN) is an early onset and severely disabling neurodegenerative disease for which no therapy is available. PKAN is caused by mutations in PANK2, which encodes for the mitochondrial enzyme
Externí odkaz:
https://doaj.org/article/f055c4ac57584474ab1daf14ac15b610
Autor:
Paolo Santambrogio, Sabrina Dusi, Michela Guaraldo, Luisa Ida Rotundo, Vania Broccoli, Barbara Garavaglia, Valeria Tiranti, Sonia Levi
Publikováno v:
Neurobiology of Disease, Vol 81, Iss , Pp 144-153 (2015)
Pantothenate kinase-associated neurodegeneration is an early onset autosomal recessive movement disorder caused by mutation of the pantothenate kinase-2 gene, which encodes a mitochondrial enzyme involved in coenzyme A synthesis. The disorder is char
Externí odkaz:
https://doaj.org/article/05aa7c3dc9fb4bccaded81d880f616af
Autor:
Camilla Ceccatelli Berti, Cristina Dallabona, Mirca Lazzaretti, Sabrina Dusi, Elena Tosi, Valeria Tiranti, Paola Goffrini
Publikováno v:
Microbial Cell, Vol 2, Iss 4, Pp 126-135 (2015)
Mutations in nuclear genes associated with defective coenzyme A biosynthesis have been identified as responsible for some forms of neurodegeneration with brain iron accumulation (NBIA), namely PKAN and CoPAN. PKAN are defined by mutations in PANK2, e
Externí odkaz:
https://doaj.org/article/55deefbd69e14a4099be894d9dc25a57
Autor:
Valeria Dolce, Sabrina Dusi, Michele Giannattasio, Chinnu Rose Joseph, Marco Fumasoni, Dana Branzei
Publikováno v:
Genes & Development. 36:167-179
Ctf4 is a conserved replisome component with multiple roles in DNA metabolism. To investigate connections between Ctf4-mediated processes involved in drug resistance, we conducted a suppressor screen of ctf4Δ sensitivity to the methylating agent MMS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0064c5a0d5cb02e6e816a6612de6d4e2
https://doi.org/10.1101/gad.349207.121
https://doi.org/10.1101/gad.349207.121
Autor:
Federica Invernizzi, Marina Mora, Valeria Tiranti, Eleonora Lamantea, Costanza Lamperti, Chiara Fiorillo, Valentina Bruno, Flavia Blasevich, Giovanni Baranello, Sabrina Dusi, Francesco Pallotti, Paola Venco, Silvia Marchet
Congenital Muscular Dystrophies (CMDs) are a heterogeneous group of autosomal recessive disorders presenting at birth with psychomotor delay, cognitive impairment, muscle weakness and hypotonia. Here we described an alteration of mitochondrial inner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611c8f6f0fd56b88549b541fb7640159
http://hdl.handle.net/11383/2097444
http://hdl.handle.net/11383/2097444
Autor:
Keiji Miyata, Sabrina Dusi, Takuya Abe, Michele Giannattasio, Kouji Hirota, Koyuki Umemura, Ryotaro Kawasumi, Yui Yoshimoto, Dana Branzei
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
AND-1/Ctf4 bridges the CMG helicase and DNA polymerase alpha, facilitating replication. Using an inducible degron system in avian cells, we find that AND-1 depletion is incompatible with proliferation, owing to cells accumulating in G2 with activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8fdc04ce310025c3223258affd3bf5
Autor:
Sonia Levi, Valeria Tiranti, Sabrina Dusi, Michela Guaraldo, Barbara Garavaglia, Vania Broccoli, Paolo Santambrogio, Luisa Ida Rotundo
Publikováno v:
Neurobiology of Disease
Neurobiology of Disease, Vol 81, Iss, Pp 144-153 (2015)
Neurobiology of Disease, Vol 81, Iss, Pp 144-153 (2015)
Pantothenate kinase-associated neurodegeneration is an early onset autosomal recessive movement disorder caused by mutation of the pantothenate kinase-2 gene, which encodes a mitochondrial enzyme involved in coenzyme A synthesis. The disorder is char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47111460d6c550971554646d7eadd0e6
Autor:
Mirca Lazzaretti, Camilla Ceccatelli Berti, Paola Goffrini, Cristina Dallabona, Valeria Tiranti, Elena Tosi, Sabrina Dusi
Publikováno v:
Microbial Cell, Vol 2, Iss 4, Pp 126-135 (2015)
Microbial Cell
Microbial Cell
Mutations in nuclear genes associated with defective coenzyme A biosynthesis have been identified as responsible for some forms of neurodegeneration with brain iron accumulation (NBIA), namely PKAN and CoPAN. PKAN are defined by mutations in PANK2, e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8346651aa211fbb4b5115043a26c21
http://microbialcell.com/researcharticles/modeling-human-coenzyme-a-synthase-mutation-in-yeast-reveals-altered-mitochondrial-function-lipid-content-and-iron-metabolism-2/
http://microbialcell.com/researcharticles/modeling-human-coenzyme-a-synthase-mutation-in-yeast-reveals-altered-mitochondrial-function-lipid-content-and-iron-metabolism-2/