Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sabrina Collins"'
Autor:
Cheryl Li, Lei Shen, Sabrina Collins, Adarsh Joshi, Subhasree Das, Kaveri Suryanarayan, Dean Bottino, Michael Curley, Dannie Wang, Michael Abadier, Ryan Larson, Xavier Parot
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/0095415875fa461a8b86d9a4ab31a7f7
Autor:
Dan T. Vogl, Shebli Atrash, Sarah A. Holstein, Omar Nadeem, Don M. Benson, Kaveri Suryanarayan, Yuyin Liu, Sabrina Collins, Xavier Parot, Jonathan L. Kaufman
Publikováno v:
Blood. 140:1357-1359
Autor:
Darayas N. Patel, Sergey S. Sarkisov, Abdalla M. Darwish, Kelly Whyte, Sabrina Collins, Crystal Smith
Publikováno v:
Optical Components and Materials XX.
Autor:
Wassilis S.C. Bruins, Rosa Rentenaar, Sabrina Collins, James F. Sampson, Niels WCJ Van De Donk, Sonja Zweegman, Tuna Mutis
Publikováno v:
Blood. 140:4236-4237
Autor:
Melissa Lynne Johnson, Raghad Abdul-Karim, David Sommerhalder, Navid Hafez, Shining Wang, Cheryl Li, Yuyin Liu, Lili Yang, Sabrina Collins, Xavier Parot, James F. Strauss
Publikováno v:
Journal of Clinical Oncology. 40:2503-2503
2503 Background: Modakafusp alfa (TAK-573) is a first-in-class immune-targeting attenuated cytokine designed to deliver attenuated interferon alpha-2b (IFNα2b) moieties to CD38-expressing cells. It consists of two attenuated IFNα2b molecules geneti
Autor:
Dannie Wang, Kaveri Suryanarayan, Sabrina Collins, Xavier Parot, Dean Bottino, Cheryl Li, Subhasree Das, Michael Abadier, Ryan Larson, Michael Curley, Lei Shen, Adarsh Joshi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background TAK-573, a humanized, anti-CD38, IgG4, monoclonal antibody genetically fused to two attenuated IFNα2b molecules, was designed for targeted delivery of attenuated IFNα2b to CD38 expressing (CD38+) cells, utilizing a unique epitope of CD38
Autor:
Helene Lelievre, Avijit Ray, Dean Bottino, Anup Zutshi, John P. Gibbs, Chirag Patel, Alex Rolfe, Marjoleen Nijsen, Brian Stoll, Alix Scholer-Dahirel, Christoph Niederalt, Sylvain Fouliard, Tomoki Yoneyama, Hoa Q Nguyen, Andy Z. X. Zhu, Sumit Bhatnagar, Christian Scheerans, Senthil Kabilan, Rolf Burghaus, Filippo Venezia, Jörg Lippert, Natalya Belousova, Serguei Soukharev, R. Adam Thompson, Jared Weddell, Georgia Lazarou, Vijayalakshmi Chelliah, Akihiro Yamada, Sabrina Collins, Haiqing Wang, Abhishek Gulati, Andrzej M. Kierzek, Heike Oberwittler, Marylore Chenel, Masayo Oishi, Piet H. van der Graaf, Sabine Wittemer-Rump, Irina Kareva, Hiroyuki Sayama
Publikováno v:
Clinical Pharmacology and Therapeutics
Drug development in oncology commonly exploits the tools of molecular biology to gain therapeutic benefit through reprograming of cellular responses. In immuno-oncology (IO) the aim is to direct the patient's own immune system to fight cancer. After
Autor:
Sabrina Collins, Sarah A. Holstein, Kaveri Suryanarayan, Maria Chaudhry, Omar Nadeem, Jonathan L. Kaufman, Xavier Parot, Murali Janakiram, Shebli Atrash, Dan T. Vogl, Yuyin Liu
Publikováno v:
Blood. 138:898-898
Background: Modakafusp alfa (previously known as TAK-573) is a first-in-class immunocytokine designed to deliver interferon alpha-2b (IFNα2b) to CD38+ cells. It consists of two attenuated IFNα2b molecules genetically fused to the Fc portion of a hu
Autor:
Xavier Parot, Sara A. Holstein, Maria Chaudhry, Omar Nadeem, Dan T. Vogl, Elizabeth O'Donnell, Sabrina Collins, Jonathan L. Kaufman, Kaveri Suryanarayan
Publikováno v:
Blood. 136:37-38
Background: TAK-573 is a first-in-class, humanized, anti-CD38, IgG4 monoclonal antibody genetically fused to 2 attenuated interferon alpha-2b (IFNα2b) molecules. The specificity for CD38 and reduced binding affinity of the attenuated IFNα molecules
Autor:
Sabrina Collins, Pia Bjorck, Michael Curley, Haiqing Wang, Jie Yu, Christina Wong, Tomoya Hara, Hong Zhang, Hiroshi Sugimoto
Publikováno v:
Cancer Research. 80:5546-5546
Background: Despite improvements in outcome for patients treated with triplet and quadruplet based regimens, multiple myeloma is still a relapsing and ultimately fatal disease. We previously reported that targeting an investigational attenuated form