Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sabrina Capo"'
Targeted Amino Acid Substitutions Impair Streptolysin O Toxicity and Group A Streptococcus Virulence
Autor:
Emiliano Chiarot, Cristina Faralla, Nico Chiappini, Giovanna Tuscano, Fabiana Falugi, Gabriella Gambellini, Annarita Taddei, Sabrina Capo, Elena Cartocci, Daniele Veggi, Alessia Corrado, Simona Mangiavacchi, Simona Tavarini, Maria Scarselli, Robert Janulczyk, Guido Grandi, Immaculada Margarit, Giuliano Bensi
Publikováno v:
mBio, Vol 4, Iss 1 (2013)
ABSTRACT Streptolysin O is a potent pore-forming toxin produced by group A Streptococcus. The aims of the present study were to dissect the relative contributions of different structural domains of the protein to hemolytic activity, to obtain a detox
Externí odkaz:
https://doaj.org/article/bb3003ecff814c90b395fe26d22ddb65
Autor:
Rebekka Lambrecht, Jasmin Jansen, Franziska Rudolf, Mohamed El-Mesery, Sabrina Caporali, Ivano Amelio, Florian Stengel, Thomas Brunner
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-11 (2024)
Abstract Cell death is a fundamental process in health and disease. Emerging research shows the existence of numerous distinct cell death modalities with similar and intertwined signaling pathways, but resulting in different cellular outcomes, raisin
Externí odkaz:
https://doaj.org/article/3a9d112a7fe24ce3b7e658370f83dc81
Autor:
Manuel Scimeca, Valentina Rovella, Sabrina Caporali, Yufang Shi, Julia Bischof, Jonathan Woodsmith, Giuseppe Tisone, Giuseppe Sica, Ivano Amelio, Gerry Melino, Alessandro Mauriello, Pierluigi Bove
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Renal cell carcinoma originates from the lining of the proximal convoluted renal tubule and represents the most common type of kidney cancer. Risk factors and comorbidities might be associated to renal cell carcinoma, while a small fraction
Externí odkaz:
https://doaj.org/article/c904afa5ec8948d3acd1283ee3170297
Autor:
Simone Fortunati, Chiara Giliberti, Marco Giannetto, Alessandro Bertucci, Sabrina Capodaglio, Elena Ricciardi, Patrizio Giacomini, Valentina Bianchi, Andrea Boni, Ilaria De Munari, Roberto Corradini, Maria Careri
Publikováno v:
Biosensors and Bioelectronics: X, Vol 15, Iss , Pp 100404- (2023)
Liquid biopsy is a non-invasive and efficient technique for the detection of tumor biomarkers in biological fluids, which currently represents a new frontier in theranostics and precision medicine. Among mutations of the KRAS oncogene, p.G12D single
Externí odkaz:
https://doaj.org/article/23305f6eed1d44ebb5bfe7f1fb3282f1
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-11 (2022)
Abstract Mutations in BAP1 have been identified in a hereditary cancer predisposition syndrome and in sporadic tumours. Individuals carrying familiar BAP1 monoallelic mutations display hypersusceptibility to exposure-associated cancers, such as asbes
Externí odkaz:
https://doaj.org/article/51b5855d8dc6496abc9759373c880700
Autor:
Tiziana Maggi, Giuliano Bensi, Sabrina Capo, Fabiana Falugi, Guido Grandi, Marirosa Mora, Chiara Zingaretti, Anna Rita Taddei, John L. Telford, Andrea G. O. Manetti
Publikováno v:
Proceedings of the National Academy of Sciences. 102:15641-15646
Although pili have long been recognized in Gram-negative pathogens as important virulence factors involved in adhesion and invasion, very little is known about extended surface organelles in Gram-positive pathogens. Here we report that Group A Strept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68cf3ae8ba2d2927012c0d8d9acf0f4a
https://doi.org/10.1073/pnas.0507808102
https://doi.org/10.1073/pnas.0507808102
Autor:
Genny Pastore, Serena Gabrielli, Roberto Giacomantonio, Gabriele Lupidi, Sabrina Capodaglio, Francesca Stella, Ezio Leone, Tommaso Compagnucci, Enrico Marcantoni
Publikováno v:
Results in Materials, Vol 15, Iss , Pp 100294- (2022)
Poly(urethane-acrylates) (PUAs) are UV-curable resins used for biomedical applications, coatings, adhesives, and many others. Their syntheses usually involve the use of aromatic diisocyanates and polyols coming from fossil-based resources, in the pre
Externí odkaz:
https://doaj.org/article/2991229e84684e6e91455f61e1d039fb
Autor:
Massimiliano Biagini, Emiliano Chiarot, Vittoria Pinto, Giuliano Bensi, John L. Telford, Nico Chiappini, Giovanna Tuscano, Sabrina Capo, James M. Musser, Fabiana Falugi, Paolo Donato, Guido Grandi, Andrea G. O. Manetti, Marirosa Mora, Renata Grifantini, Massimo Mariani, Immaculada Margarit, Manuela Garibaldi, Robert Janulczyk, Maria Scarselli, Erwin Swennen, Marilena Gallotta, Mauro Bombaci, Nathalie Norais
Publikováno v:
Molecular & Cellular Proteomics : MCP
We propose an experimental strategy for highly accurate selection of candidates for bacterial vaccines without using in vitro and/or in vivo protection assays. Starting from the observation that efficacious vaccines are constituted by conserved, surf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86813082e208921333c02b13c67daf73
http://europepmc.org/articles/PMC3433891
http://europepmc.org/articles/PMC3433891
Autor:
William J. Christ, Marilena Gallotta, Giuliano Bensi, Sabrina Capo, Guido Grandi, John Pena, Paola Fontani, Erwin Swennen, Peter H. Seeberger, Roberto Adamo, Daniela Proietti, Giada Buffi, Emiliano Chiarot, Anna Kabanova, Vittoria Pinto, Daniele Casini, Rino Rappuoli, Francesco Berti, Emilia Cappelletti, David A. G. Skibinski, Paolo Costantino, Maria Rosaria Romano, Immaculada Margarit, A. Stewart Campbell
Publikováno v:
Vaccine. 29(1)
Bacterial infections caused by Group A Streptococcus (GAS) are a serious health care concern that currently cannot be prevented by vaccination. The GAS cell-wall polysaccharide (GAS-PS) is an attractive vaccine candidate due to its constant expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eca9e94c14d064aeed37222ce8f0c5f
https://pubmed.ncbi.nlm.nih.gov/20870056
https://pubmed.ncbi.nlm.nih.gov/20870056
Autor:
Sabrina Capo, John L. Telford, Chiara Zingaretti, Fabiana Falugi, Guido Grandi, Andrea G. O. Manetti, Massimo Mariani, Laura Amodeo, James M. Musser, Immaculada Margarit, Graziella Orefici, Marirosa Mora, Vittoria Pinto
Publikováno v:
The Journal of infectious diseases. 198(12)
Background We previously reported that group A Streptococcus (GAS) pili are the T antigens described by Rebecca Lancefield. We also showed that these pili, constituted by backbone, ancillary 1, and ancillary 2 proteins, confer protection against GAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fae2c7b299972f6e733972a555d9ed6
https://pubmed.ncbi.nlm.nih.gov/18928376
https://pubmed.ncbi.nlm.nih.gov/18928376