Výsledky vyhledávání - "Sabrina Bellenfant"

Development of an innervated tissue-engineered skin with human sensory neurons and Schwann cells differentiated from iPS cells

Autor: Quentin Muller, Vincent Flacher, Sabrina Bellenfant, François Berthod, Thiéry De Serres-Bérard, Marie-Josée Beaudet

Publikováno v: Acta Biomaterialia
Acta Biomaterialia, 2018, 82, ⟨10.1016/j.actbio.2018.10.011⟩

Cutaneous innervation is increasingly recognized as a major element of skin physiopathology through the neurogenic inflammation driven by neuropeptides that are sensed by endothelial cells and the immune system. To investigate this process in vitro,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80bf3fad81fd45bd4d8c15563ceebdda

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Sensory Neurons Accelerate Skin Reepithelialization via Substance P in an Innervated Tissue-Engineered Wound Healing Model

Autor: Sabrina Bellenfant, François Berthod, Marie-Anne Germain, Sébastien Cadau, Lorene Mottier, Mathieu Blais

Publikováno v: Tissue Engineering Part A. 20:2180-2188

Keratinocytes are responsible for reepithelialization and restoration of the epidermal barrier during wound healing. The influence of sensory neurons on this mechanism is not fully understood. We tested whether sensory neurons influence wound closure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3623eb890abd404e3ec4821efd053ea
https://doi.org/10.1089/ten.tea.2013.0535

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Extended-Synaptotagmin-2 Mediates FGF Receptor Endocytosis and ERK Activation In Vivo

Autor: Michel G. Tremblay, Sabrina Bellenfant, Joëlle Baril, François Guillou, Steve Jean, Tom Moss, Alexander Mikryukov

Publikováno v: Developmental Cell. 19(3):426-439

SummaryTargeting of activated plasma membrane receptors to endocytic pathways is important in determining the outcome of growth factor signaling. However, the molecular mechanisms are still poorly understood. Here, we show that the synaptotagmin-rela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53815ebab09adee2e829fc745c66830

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High yield extraction of pure spinal motor neurons, astrocytes and microglia from single embryo and adult mouse spinal cord

Autor: Qiurui Yang, Sabrina Bellenfant, François Gros-Louis, François Berthod, Sébastien Cadau, Mathieu Blais, Marie-Josée Beaudet

Publikováno v: Scientific Reports

Extraction of mouse spinal motor neurons from transgenic mouse embryos recapitulating some aspects of neurodegenerative diseases like amyotrophic lateral sclerosis has met with limited success. Furthermore, extraction and long-term culture of adult m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7171bb339e038c737f2013ca058a5ec1
https://pubmed.ncbi.nlm.nih.gov/26577180

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Nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3 and glial-derived neurotrophic factor enhance angiogenesis in a tissue-engineered in vitro model

Autor: Sabrina Bellenfant, Mathieu Blais, Philippe Lévesque, François Berthod

Publikováno v: Tissue engineering. Part A. 19(15-16)

Skin is a major source of secretion of the neurotrophic factors nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and glial-derived neurotrophic factor (GDNF) controlling cutaneous sensory innervation. Beside

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711cc8b85c4024931e8a71ec2c9e84df
https://pubmed.ncbi.nlm.nih.gov/23530859

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Extended synaptotagmin interaction with the fibroblast growth factor receptor depends on receptor conformation, not catalytic activity

Autor: Joëlle Baril, Sabrina Bellenfant, Tom Moss, Michel G. Tremblay, François Guillou, Prakash K. Mishra, Chelsea Herdman

Publikováno v: Journal of Biological Chemistry. 291:3173

We previously demonstrated that ESyt2 interacts specifically with the activated FGF receptor and is required for a rapid phase of receptor internalization and for functional signaling via the ERK pathway in early Xenopus embryos. ESyt2 is one of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ea0e9f0654fe78b55dd7ecda31a487
https://doi.org/10.1074/jbc.a115.656918

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