Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sabrina Asteriti"'
A hybrid stochastic/deterministic model of single photon response and light adaptation in mouse rods
Autor:
Charlotte Johanna Beelen, Sabrina Asteriti, Lorenzo Cangiano, Karl-Wilhelm Koch, Daniele Dell'Orco
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3720-3734 (2021)
The phototransduction cascade is paradigmatic for signaling pathways initiated by G protein-coupled receptors and is characterized by a fine regulation of photoreceptor sensitivity and electrical response to a broad range of light stimuli. Here, we p
Externí odkaz:
https://doaj.org/article/dfc8fbd2104e4d029ea6324798957ca3
Autor:
Sabrina Asteriti, Lorenzo Cangiano
Publikováno v:
HardwareX, Vol 8, Iss , Pp e00155- (2020)
Effective temperature control is crucial in many studies of isolated biological tissues, with preparations often requiring specialized holding chambers. In these situations, the design flexibility and optimizations offered by a custom made temperatur
Externí odkaz:
https://doaj.org/article/a585a622d529499ea45c6d577c4de2db
Publikováno v:
eLife, Vol 4 (2015)
Vertebrates acquired dim-light vision when an ancestral cone evolved into the rod photoreceptor at an unknown stage preceding the last common ancestor of extant jawed vertebrates (∼420 million years ago Ma). The jawless lampreys provide a unique op
Externí odkaz:
https://doaj.org/article/4075c03c3c6641c7b23707b4ad6cd1de
Publikováno v:
eLife, Vol 3 (2014)
Rod and cone photoreceptors are coupled by gap junctions (GJs), relatively large channels able to mediate both electrical and molecular communication. Despite their critical location in our visual system and evidence that they are dynamically gated f
Externí odkaz:
https://doaj.org/article/f4cef815bea342c0b9afa68cd9671f23
Autor:
Sabrina Asteriti, Valerio Marino, Anna Avesani, Amedeo Biasi, Giuditta Dal Cortivo, Lorenzo Cangiano, Daniele Dell’Orco
Retinal dystrophies of genetic origin are often associated with mutations in the genes involved in the phototransduction cascade in photoreceptors, a paradigmatic signaling pathway mediated by G protein-coupled receptors. Photoreceptor viability is s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5ad8bae4b81dae8a09c6619f6f8b6ec
https://doi.org/10.1101/2022.11.10.516027
https://doi.org/10.1101/2022.11.10.516027
A hybrid stochastic/deterministic model of single photon response and light adaptation in mouse rods
Autor:
Sabrina Asteriti, Karl-Wilhelm Koch, Charlotte Johanna Beelen, Daniele Dell'Orco, Lorenzo Cangiano
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 3720-3734 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Highlights • A hybrid stochastic/deterministic model of mouse rod phototransduction is presented. • Rod photocurrent to photovoltage conversion in darkness is accurately characterized. • Photoresponses to dim and bright
Highlights • A hybrid stochastic/deterministic model of mouse rod phototransduction is presented. • Rod photocurrent to photovoltage conversion in darkness is accurately characterized. • Photoresponses to dim and bright
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8136acd6ea6a307ba719e270e61c52a1
http://www.sciencedirect.com/science/article/pii/S2001037021002713
http://www.sciencedirect.com/science/article/pii/S2001037021002713
Autor:
Craig Montell, Weidi Chen, Mingjie Zhang, Ziling Sun, Fei Ye, Sabrina Asteriti, Wei Liu, Jun Wan, Roger C. Hardie, Zijing Chen, Zeyu Shen
Drosophila TRP is a calcium-permeable cation channel essential for fly visual signal transduction. During phototransduction, Ca2+ mediates both positive and negative feedback regulation on TRP channel activity, possibly via binding to calmodulin (CaM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbfe902897861fe824a8f50b4eece834
https://www.repository.cam.ac.uk/handle/1810/315747
https://www.repository.cam.ac.uk/handle/1810/315747
Tissue clearing techniques are undergoing a renaissance motivated by the need to image fluorescent neurons, and other cells, deep in the sample without physical sectioning. Optical transparency is achieved by equilibrating tissues with high refractiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db44dfbb287b6a19322841e3d516a9e6
http://hdl.handle.net/11568/1018898
http://hdl.handle.net/11568/1018898
A crucial role in ejaculation is thought to be played by a population of lumbar spino-thalamic neurons (LSt), which express galanin and other neuropeptides. In rats, these neurons are activated with ejaculation and their lesion selectively abolishes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4534b1086ff2e67ee9afda2b1943e48e
http://hdl.handle.net/11568/1018891
http://hdl.handle.net/11568/1018891
Autor:
Martin Biel, Mathias W. Seeliger, Sabrina Asteriti, Christian Schön, Vithiyanjali Sothilingam, Jochen Herms, Stylianos Michalakis, Naoyuki Tanimoto, Susanne Koch, Marina Garcia Garrido, Lorenzo Cangiano
Publikováno v:
Human molecular genetics 25(6), 1165-1175 (2016). doi:10.1093/hmg/ddv639
Most inherited blinding diseases are characterized by compromised retinal function and progressive degeneration of photoreceptors. However, the factors that affect the life span of photoreceptors in such degenerative retinal diseases are rather poorl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8f8c6b1faf1e1bcaeeee5f0b4e42b7
https://doi.org/10.1093/hmg/ddv639
https://doi.org/10.1093/hmg/ddv639