Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Sabrina A, Hogan"'
Autor:
Simon Burgermeister, Hubert S. Gabryś, Lucas Basler, Sabrina A. Hogan, Matea Pavic, Marta Bogowicz, Julia M. Martínez Gómez, Diem Vuong, Stephanie Tanadini-Lang, Robert Foerster, Martin W. Huellner, Reinhard Dummer, Mitchell P. Levesque, Matthias Guckenberger
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
PurposeWe explored imaging and blood bio-markers for survival prediction in a cohort of patients with metastatic melanoma treated with immune checkpoint inhibition.Materials and Methods94 consecutive metastatic melanoma patients treated with immune c
Externí odkaz:
https://doaj.org/article/df2738f114d24e2a825402237ac970e7
Autor:
Joachim G J V Aerts, Ron H J Mathijssen, Sjoerd H van der Burg, Reinhard Dummer, Reno Debets, Mandy van Brakel, Ellen Kapiteijn, Daan P Hurkmans, Els M E Verdegaal, Sabrina A Hogan, Rik de Wijn, Lies Hovestad, Dianne M A van den Heuvel, Rob Ruijtenbeek, Marij J P Welters, Edwin A Basak, Herbert M Pinedo, Cor H J Lamers, Harmen J G van de Werken, John P Groten, Mitchell P Levesque
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Many cancer patients do not obtain clinical benefit from immune checkpoint inhibition. Checkpoint blockade targets T cells, suggesting that tyrosine kinase activity profiling of baseline peripheral blood mononuclear cells may predict clini
Externí odkaz:
https://doaj.org/article/fdec7b4cc229438683584ce62dfcc0e3
Autor:
Mitchell P. Levesque, Reinhard Dummer, John B.A.G. Haanen, Nicolas Pasqual, Pia Kvistborg, Marieke I.G. Raaijmakers, Thi Dan Linh Nguyen-Kim, Jean-François Mouret, Nadia Plantier, Solène Perez, Manuarii Manuel, Simone M. Goldinger, Nicoletta F. Jaberg-Bentele, Phil F. Cheng, Anaïs Courtier, Sabrina A. Hogan
Effect of previous treatment on variables tested in our model. (Kruskal-Wallis test)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71178e5a80d611fbb75de15696c89e9b
https://doi.org/10.1158/2326-6066.22536035
https://doi.org/10.1158/2326-6066.22536035
Autor:
Mitchell P. Levesque, Reinhard Dummer, John B.A.G. Haanen, Nicolas Pasqual, Pia Kvistborg, Marieke I.G. Raaijmakers, Thi Dan Linh Nguyen-Kim, Jean-François Mouret, Nadia Plantier, Solène Perez, Manuarii Manuel, Simone M. Goldinger, Nicoletta F. Jaberg-Bentele, Phil F. Cheng, Anaïs Courtier, Sabrina A. Hogan
Figure Legends for Supplemental Figures 1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25269a334a7acee2caf869b2771c70d3
https://doi.org/10.1158/2326-6066.22536020
https://doi.org/10.1158/2326-6066.22536020
Autor:
Mitchell P. Levesque, Reinhard Dummer, John B.A.G. Haanen, Nicolas Pasqual, Pia Kvistborg, Marieke I.G. Raaijmakers, Thi Dan Linh Nguyen-Kim, Jean-François Mouret, Nadia Plantier, Solène Perez, Manuarii Manuel, Simone M. Goldinger, Nicoletta F. Jaberg-Bentele, Phil F. Cheng, Anaïs Courtier, Sabrina A. Hogan
Many metastatic melanoma patients experience durable responses to anti-PD1 and/or anti-CTLA4; however, a significant proportion (over 50%) do not benefit from the therapies. In this study, we sought to assess pretreatment liquid biopsies for biomarke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1af8cde818efcf21e10b8eaa589b0b65
https://doi.org/10.1158/2326-6066.c.6548021.v1
https://doi.org/10.1158/2326-6066.c.6548021.v1
Autor:
Julia Newton-Bishop, D. Timothy Bishop, Graham P. Cook, Mitchell P. Levesque, Sandra Nicole Freiberger, Sabrina A. Hogan, Sathya Muralidhar, Juliette A. Randerson-Moor, Tracey Mell, John R. Davies, Mark Harland, Anastasia Filia, Alastair P. Droop, Joey Mark S. Diaz, Sally J. O’Shea, Jonathan P. Laye, Jérémie Nsengimana, Joanna Poźniak
The immune response to melanoma improves the survival in untreated patients and predicts the response to immune checkpoint blockade. Here, we report genetic and environmental predictors of the immune response in a large primary cutaneous melanoma coh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1806e41b3116939a2773cdc2d6761d28
https://doi.org/10.1158/0008-5472.c.6510066.v1
https://doi.org/10.1158/0008-5472.c.6510066.v1
Autor:
Julia Newton-Bishop, D. Timothy Bishop, Graham P. Cook, Mitchell P. Levesque, Sandra Nicole Freiberger, Sabrina A. Hogan, Sathya Muralidhar, Juliette A. Randerson-Moor, Tracey Mell, John R. Davies, Mark Harland, Anastasia Filia, Alastair P. Droop, Joey Mark S. Diaz, Sally J. O’Shea, Jonathan P. Laye, Jérémie Nsengimana, Joanna Poźniak
Gene lists per immune cell type after successive filtration steps.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317f1910dfc59cb6b9a7bdf9b593a4a2
https://doi.org/10.1158/0008-5472.22418220
https://doi.org/10.1158/0008-5472.22418220
Autor:
Mitchell P. Levesque, Matthias Guckenberger, Reinhard Dummer, Martin W. Huellner, Ken Kudura, Robert Förster, Stephanie Tanadini-Lang, Diem Vuong, Marta Bogowicz, Matea Pavic, Sabrina A. Hogan, Hubert S. Gabryś, Lucas Basler
Partial dependence plots of the multivariate models for PP-prediction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0379443b345b207eb20c73f28cf68144
https://doi.org/10.1158/1078-0432.22478066.v1
https://doi.org/10.1158/1078-0432.22478066.v1
Autor:
Mitchell P. Levesque, Matthias Guckenberger, Reinhard Dummer, Martin W. Huellner, Ken Kudura, Robert Förster, Stephanie Tanadini-Lang, Diem Vuong, Marta Bogowicz, Matea Pavic, Sabrina A. Hogan, Hubert S. Gabryś, Lucas Basler
Summary of patient outcome of the individual groups (with landmark analysis) The landmark method was applied, that is all events before 5 months were excluded. 95% confidence intervals were provided in parentheses. PP-only patients were the best perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de6faa5ac53a392cff70fd257f523d2
https://doi.org/10.1158/1078-0432.22478057.v1
https://doi.org/10.1158/1078-0432.22478057.v1
Autor:
Julia Newton-Bishop, D. Timothy Bishop, Graham P. Cook, Mitchell P. Levesque, Sandra Nicole Freiberger, Sabrina A. Hogan, Sathya Muralidhar, Juliette A. Randerson-Moor, Tracey Mell, John R. Davies, Mark Harland, Anastasia Filia, Alastair P. Droop, Joey Mark S. Diaz, Sally J. O’Shea, Jonathan P. Laye, Jérémie Nsengimana, Joanna Poźniak
Additional information on methods used and supplementary figures and tables. Figure S1: Schematic summary of consensus clustering; Figure S2: Comparison of the newly obtained immune subgroups with two published melanoma molecular signatures; Figure S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fc313ce7fc3b61dcf39faa6f033b94
https://doi.org/10.1158/0008-5472.22418214
https://doi.org/10.1158/0008-5472.22418214