Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sabrina, Tassini"'
Autor:
Daniela Pompilio, Sabrina Tassini, Laura Piccoli, Alessio Barilli, Aldo Feriani, Daniela Brodbeck, Laura Castelletti, Raveglia Luca Francesco, Laurent Brault, Iain Lingard, Laura Aldegheri, Federica Bianchi, Mark Sabat, Richard M. Myers, Caterina Virginio, Selena Nola, Cristian Salvagno
Publikováno v:
Journal of Medicinal Chemistry. 64:5931-5955
Transient receptor potential cation channel subfamily M member 5 (TRPM5) is a nonselective monovalent cation channel activated by intracellular Ca2+ increase. Within the gastrointestinal system, TRPM5 is expressed in the stoma, small intestine, and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::276f841154741494c801408c590e8d10
https://doi.org/10.1021/acs.jmedchem.1c00065
https://doi.org/10.1021/acs.jmedchem.1c00065
Autor:
Alessio, Barilli, Laura, Aldegheri, Federica, Bianchi, Laurent, Brault, Daniela, Brodbeck, Laura, Castelletti, Aldo, Feriani, Iain, Lingard, Richard, Myers, Selena, Nola, Laura, Piccoli, Daniela, Pompilio, Luca F, Raveglia, Cristian, Salvagno, Sabrina, Tassini, Caterina, Virginio, Mark, Sabat
Publikováno v:
Journal of medicinal chemistry. 64(9)
Transient receptor potential cation channel subfamily M member 5 (TRPM5) is a nonselective monovalent cation channel activated by intracellular Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d619050999d16fbf323a8d84594fd590
https://pubmed.ncbi.nlm.nih.gov/33890770
https://pubmed.ncbi.nlm.nih.gov/33890770
Autor:
Claudio Zamperini, Paola Vergani, Giulia Tagliavini, Miroslava Kissova, Emily Langron, Greta Fontò, Kristina Lanko, Simona Bertoni, Luisa Ragionieri, Simone Palese, Marco Radi, Giovanni Maga, Emmanuele Crespan, Francesca Ravanetti, Elena Dreassi, Sabrina Tassini, Leen Delang, Johan Neyts, Carmen Mirabelli, Carmine Giorgio, Arianna Mancini
Cystic fibrosis (CF) is a multiorgan disease caused by mutations of the cystic fibrosis transmembrane conductance regulator (CFTR). In addition to respiratory impairment due to mucus accumulation, viruses and bacteria trigger acute pulmonary exacerba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99263645f48f3ea20e4668388cbed286
https://lirias.kuleuven.be/handle/123456789/646383
https://lirias.kuleuven.be/handle/123456789/646383
Autor:
Gabriele Costantino, Miroslava Kissova, Jorge I. Armijos-Rivera, Daniele Castagnolo, Marco Radi, Nicolò Scalacci, Federica Giagnorio, Giovanni Maga, Sabrina Tassini, Emmanuele Crespan
Publikováno v:
MedChemComm. 7:484-494
Herein we report the development of a new versatile chemical tool for the rapid identification of LRRK2-targeting probes as potential anti-Parkinson's agents. Based on the structure of recently identified inhibitors, we decided to develop a new multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66b4e1698315a6d4979ef8c31c09a1d6
https://doi.org/10.1039/c5md00462d
https://doi.org/10.1039/c5md00462d
Autor:
Sanja Glisic, Elisa Azzali, Vladimir Perovic, Jelica Vucicevic, Nevena Veljkovic, Tatjana Srdic-Rajic, Sabrina Tassini, Marco Pieroni, Katarina Nikolic, Marco Radi, Gabriele Costantino, Jonne M. Laurila, Mika Scheinin, Danica Agbaba
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic & Medicinal Chemistry
Bioorganic & Medicinal Chemistry
The clonidine-like central antihypertensive agent rilmenidine, which has high affinity for I-1-type imidazoline receptors (I-1-IR) was recently found to have cytotoxic effects on cultured cancer cell lines. However, due to its pharmacological effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba237774b4c301d79cd83603b610ebe6
https://doi.org/10.1016/j.bmc.2016.05.043
https://doi.org/10.1016/j.bmc.2016.05.043
Autor:
Marco Radi, Alessandra Nigro, Elena Spina, Gabriele Costantino, Gabriele Carullo, Sabrina Tassini, Francescsa Aiello, Francesca Giordano, Antonio Garofalo, Agostino Bruno, Paolo Vincetti
Publikováno v:
ChemMedChem. 12(16)
Together with estrogen receptors ERα and ERβ, the G protein-coupled estrogen receptor (GPER) mediates important pathophysiological signaling pathways induced by estrogens and is currently regarded as a promising target for ER-negative (ER-) and tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a422e5a221a97695ab07cc99e1381f
https://pubmed.ncbi.nlm.nih.gov/28520140
https://pubmed.ncbi.nlm.nih.gov/28520140
Autor:
Jelica Vucicevic, Marco Radi, Veljko Veljkovic, Sanja Glisic, Nevena Veljkovic, Sabrina Tassini
Publikováno v:
Expert opinion on drug discovery. 10(6)
Maraviroc is a first-in-class antiretroviral (ARV) drug acting on a host cell target (CCR5), which blocks the entry of the HIV virus into the cell. Maraviroc is currently indicated for combination ARV treatment in adults infected only with CCR5-tropi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77cad4ebdc42b8c4001d648806f1eef4
https://pubmed.ncbi.nlm.nih.gov/25927601
https://pubmed.ncbi.nlm.nih.gov/25927601