Zobrazeno 1 - 10
of 547
pro vyhledávání: '"Sabrina, Pricl"'
Autor:
Gabriele Cavalieri, Domenico Marson, Nicoletta Giurgevich, Rachele Valeri, Fulvia Felluga, Erik Laurini, Sabrina Pricl
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 533 (2024)
Dendrimers, intricate macromolecules with highly branched nanostructures, offer unique attributes including precise control over size, shape, and functionality, making them promising candidates for a wide range of biomedical applications. The explora
Externí odkaz:
https://doaj.org/article/3bd63c41819b4bd0ae73568d58da57cd
Autor:
Friedrich-Alexander Ludwig, Erik Laurini, Judith Schmidt, Sabrina Pricl, Winnie Deuther-Conrad, Bernhard Wünsch
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 166 (2024)
σ1 receptors play a crucial role in various neurological and neurodegenerative diseases including pain, psychosis, Alzheimer’s disease, and depression. Spirocyclic piperidines represent a promising class of potent σ1 receptor ligands. The relatio
Externí odkaz:
https://doaj.org/article/0a3bc1da7d3848428725bd959f3c6d57
Autor:
Stefano Rosa, Andrea Tagliani, Chiara Bertaso, Luca Tadini, Cristina Visentin, Louise Jane Gourlay, Sabrina Pricl, Lucia Feni, Sara Pellegrino, Paolo Pesaresi, Simona Masiero
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Genetically-encoded combinatorial peptide libraries are convenient tools to identify peptides to be used as therapeutics, antimicrobials and functional synthetic biology modules. Here, we report the identification and characterization of a cyclic pep
Externí odkaz:
https://doaj.org/article/856190be0ecb44fb812a33bb4087f433
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
Abstract The purpose of this work is to provide an in silico molecular rationale of the role eventually played by currently circulating mutations in the receptor binding domain of the SARS-CoV-2 spike protein (S-RBDCoV‑2) in evading the immune surv
Externí odkaz:
https://doaj.org/article/4145f5808f704f6889ff00b5369faa2b
Autor:
Juan Liu, Chao Chen, Tuo Wei, Odile Gayet, Céline Loncle, Laurence Borge, Nelson Dusetti, Xiaowei Ma, Domenico Marson, Erik Laurini, Sabrina Pricl, Zhongwei Gu, Juan Iovanna, Ling Peng, Xing‐Jie Liang
Publikováno v:
Exploration, Vol 1, Iss 1, Pp 21-34 (2021)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer with no efficacious treatment. The application of nanomedicine is expected to bring new hope to PDAC treatment. In this study, we report a novel supramolecular dendrimeric nanosystem
Externí odkaz:
https://doaj.org/article/25d176e235ed4690b1b1a9d6ceb43f3d
Autor:
Sabrina Pricl
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 2013 (2023)
COST Action CA17140 Cancer Nanomedicine—from the bench to the bedside (Nano2Clinic,) is the first, pan-European interdisciplinary network of representatives from academic institutions and small and medium enterprises including clinical research org
Externí odkaz:
https://doaj.org/article/1cf4fb70857f439abe7907e2efbc52d4
Autor:
Stefano Stassi, Monica Marini, Marco Allione, Sergei Lopatin, Domenico Marson, Erik Laurini, Sabrina Pricl, Candido Fabrizio Pirri, Carlo Ricciardi, Enzo Di Fabrizio
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Intercalating molecules can significantly change the conformation of DNA. Here, the authors fabricated resonators fully composed of DNA forming bundles between microfabricated pillars to study the vibration property of the DNA bundles with/without in
Externí odkaz:
https://doaj.org/article/1df5a0fd518d4a9b9c962d7616f37f53
Publikováno v:
Applied Sciences, Vol 12, Iss 17, p 8766 (2022)
Metal replacements for automotive and aerospace components are already a consolidated reality, in light of the advantages offered by fibre-reinforced polymers, consisting of reduced costs, weight, and environmental impact. As a result, engineering ha
Externí odkaz:
https://doaj.org/article/a4889b8587fc44bd9b21e3ca633df255
Autor:
Luca Blicker, Rafael González-Cano, Erik Laurini, Francisco R. Nieto, Judith Schmidt, Dirk Schepmann, Sabrina Pricl, Bernhard Wünsch
Publikováno v:
Journal of Medicinal Chemistry. 66:4999-5020
Autor:
Martín Estrada-Valencia, Clara Herrera-Arozamena, Concepción Pérez, Dolores Viña, José A. Morales-García, Ana Pérez-Castillo, Eva Ramos, Alejandro Romero, Erik Laurini, Sabrina Pricl, María Isabel Rodríguez-Franco
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 712-727 (2019)
The design of multi-target directed ligands (MTDLs) is a valid approach for obtaining effective drugs for complex pathologies. MTDLs that combine neuro-repair properties and block the first steps of neurotoxic cascades could be the so long wanted rem
Externí odkaz:
https://doaj.org/article/ed3ffb901f804e3298167947f93fccbc