Risk willingness in multiple system atrophy and Parkinson’s disease understanding patient preferences

Autor: Alexander Maximilian Bernhardt, Marc Oeller, Isabel Friedrich, Emre Kocakavuk, Eliana Nachman, Kevin Peikert, Malte Roderigo, Andreas Rossmann, Tabea Schröter, Lea Olivia Wilhelm, Tino Prell, Christoph van Riesen, Johanna Nieweler, Sabrina Katzdobler, Markus Weiler, Heike Jacobi, Tobias Warnecke, Inga Claus, Carla Palleis, Stephan Breimann, Björn Falkenburger, Moritz Brandt, Andreas Hermann, Jost-Julian Rumpf, Joseph Claßen, Günter Höglinger, Florin Gandor, Johannes Levin, Armin Giese, Annette Janzen, Wolfgang Hermann Oertel

Publikováno v: npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-10 (2024)

Abstract Disease-modifying therapeutics in the α-synucleinopathies multiple system atrophy (MSA) and Parkinson’s Disease (PD) are in early phases of clinical testing. Involving patients’ preferences including therapy-associated risk willingness

Externí odkaz: https://doaj.org/article/4720aaf03e8d4e84ab5498ef530462a6

Precision Balance Assessment in Parkinson’s Disease: Utilizing Vision-Based 3D Pose Tracking for Pull Test Analysis

Autor: Nina Ellrich, Kasimir Niermeyer, Daniela Peto, Julian Decker, Urban M. Fietzek, Sabrina Katzdobler, Günter U. Höglinger, Klaus Jahn, Andreas Zwergal, Max Wuehr

Publikováno v: Sensors, Vol 24, Iss 11, p 3673 (2024)

Postural instability is a common complication in advanced Parkinson’s disease (PD) associated with recurrent falls and fall-related injuries. The test of retropulsion, consisting of a rapid balance perturbation by a pull in the backward direction,

Externí odkaz: https://doaj.org/article/906a50a86e784de0859bb4e0fc2c6148

Tau deposition patterns are associated with functional connectivity in primary tauopathies

Autor: Nicolai Franzmeier, Matthias Brendel, Leonie Beyer, Luna Slemann, Gabor G. Kovacs, Thomas Arzberger, Carolin Kurz, Gesine Respondek, Milica J. Lukic, Davina Biel, Anna Rubinski, Lukas Frontzkowski, Selina Hummel, Andre Müller, Anika Finze, Carla Palleis, Emanuel Joseph, Endy Weidinger, Sabrina Katzdobler, Mengmeng Song, Gloria Biechele, Maike Kern, Maximilian Scheifele, Boris-Stephan Rauchmann, Robert Perneczky, Michael Rullman, Marianne Patt, Andreas Schildan, Henryk Barthel, Osama Sabri, Jost J. Rumpf, Matthias L. Schroeter, Joseph Classen, Victor Villemagne, John Seibyl, Andrew W. Stephens, Edward B. Lee, David G. Coughlin, Armin Giese, Murray Grossman, Corey T. McMillan, Ellen Gelpi, Laura Molina-Porcel, Yaroslau Compta, John C. van Swieten, Laura Donker Laat, Claire Troakes, Safa Al-Sarraj, John L. Robinson, Sharon X. Xie, David J. Irwin, Sigrun Roeber, Jochen Herms, Mikael Simons, Peter Bartenstein, Virginia M. Lee, John Q. Trojanowski, Johannes Levin, Günter Höglinger, Michael Ewers

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)

Tau pathology drives neuronal dysfunction in 4- repeat tauopathies. Here, the authors combine tau-PET, resting-state fMRI and histopathology data, to show that brain connectivity is associated with tau deposition patterns in 4-repeat tauopathies.

Externí odkaz: https://doaj.org/article/bd1a4c237aa0450eb6ad79b56669c4c6

Serum glial fibrillary acidic protein and neurofilament light chain in patients with early treated phenylketonuria

Autor: Amelie S. Lotz-Havla, Sabrina Katzdobler, Brigitte Nuscher, Katharina Weiß, Johannes Levin, Joachim Havla, Esther M. Maier

Publikováno v: Frontiers in Neurology, Vol 13 (2022)

To pave the way for healthy aging in early treated phenylketonuria (ETPKU) patients, a better understanding of the neurological course in this population is needed, requiring easy accessible biomarkers to monitor neurological disease progression in l

Externí odkaz: https://doaj.org/article/00476ec0bb51462ca8ad272ec72869df

Assessment of perfusion deficit with early phases of [18F]PI-2620 tau-PET versus [18F]flutemetamol-amyloid-PET recordings

Autor: Friederike Völter, Leonie Beyer, Florian Eckenweber, Maximilian Scheifele, Ngoc Bui, Marianne Patt, Henryk Barthel, Sabrina Katzdobler, Carla Palleis, Nicolai Franzmeier, Johannes Levin, Robert Perneczky, Boris-Stephan Rauchmann, Osama Sabri, Jimin Hong, Paul Cumming, Axel Rominger, Kuangyu Shi, Peter Bartenstein, Matthias Brendel

Publikováno v: European journal of nuclear medicine and molecular imaging 50, 1384-1394 (2023). doi:10.1007/s00259-022-06087-y
Völter, Friederike; Beyer, Leonie; Eckenweber, Florian; Scheifele, Maximilian; Bui, Ngoc; Patt, Marianne; Barthel, Henryk; Katzdobler, Sabrina; Palleis, Carla; Franzmeier, Nicolai; Levin, Johannes; Perneczky, Robert; Rauchmann, Boris-Stephan; Sabri, Osama; Hong, Jimin; Cumming, Paul; Rominger, Axel; Shi, Kuangyu; Bartenstein, Peter and Brendel, Matthias (2023). Assessment of perfusion deficit with early phases of [18F]PI-2620 tau-PET versus [18F]flutemetamol-amyloid-PET recordings. European journal of nuclear medicine and molecular imaging, 50(5), pp. 1384-1394. Springer 10.1007/s00259-022-06087-y

Purpose Characteristic features of amyloid-PET (A), tau-PET (T), and FDG-PET (N) can serve for the A/T/N classification of neurodegenerative diseases. Recent studies showed that the early, perfusion-weighted phases of amyloid- or tau-PET recordings s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57997d985133675880d9ad8d44f0ae70
https://doi.org/10.1007/s00259-022-06087-y