Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Sabrina, Fritah"'
Autor:
Anne Dirkse, Anna Golebiewska, Thomas Buder, Petr V. Nazarov, Arnaud Muller, Suresh Poovathingal, Nicolaas H. C. Brons, Sonia Leite, Nicolas Sauvageot, Dzjemma Sarkisjan, Mathieu Seyfrid, Sabrina Fritah, Daniel Stieber, Alessandro Michelucci, Frank Hertel, Christel Herold-Mende, Francisco Azuaje, Alexander Skupin, Rolf Bjerkvig, Andreas Deutsch, Anja Voss-Böhme, Simone P. Niclou
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Cancer stem cells (CSCs) comprise a putative population that can drive growth and resistance. Here, in glioblastoma models the authors show that rather than being a distinct clonal entity, the CSC population represents a plastic state adoptable by mo
Externí odkaz:
https://doaj.org/article/f9953d80d7214efbbab8832d2c810d81
Autor:
Ali Kishk, Maria Pires Pacheco, Tony Heurtaux, Lasse Sinkkonen, Jun Pang, Sabrina Fritah, Simone P. Niclou, Thomas Sauter
Publikováno v:
Cells, Vol 11, Iss 16, p 2486 (2022)
Brain disorders represent 32% of the global disease burden, with 169 million Europeans affected. Constraint-based metabolic modelling and other approaches have been applied to predict new treatments for these and other diseases. Many recent studies f
Externí odkaz:
https://doaj.org/article/a832935e117749fea6cbbd17e92b7f65
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 9825
By generating protein diversity, alternative splicing provides an important oncogenic pathway. Isocitrate dehydrogenase (IDH) 1 and 2 mutations and 1p/19q co-deletion have become crucial for the novel molecular classification of diffuse gliomas, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::4e9a0f8bde78e61f5145542151458db1
Autor:
Fred Fack, Saverio Tardito, Guillaume Hochart, Anais Oudin, Liang Zheng, Sabrina Fritah, Anna Golebiewska, Petr V Nazarov, Amandine Bernard, Ann‐Christin Hau, Olivier Keunen, William Leenders, Morten Lund‐Johansen, Jonathan Stauber, Eyal Gottlieb, Rolf Bjerkvig, Simone P Niclou
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 12, Pp 1681-1695 (2017)
Abstract Heterozygous mutations in NADP‐dependent isocitrate dehydrogenases (IDH) define the large majority of diffuse gliomas and are associated with hypermethylation of DNA and chromatin. The metabolic dysregulations imposed by these mutations, w
Externí odkaz:
https://doaj.org/article/a8ba6af621ad46c095e3b4d5984a5b21
Autor:
Pierre Lapaquette, Sabrina Fritah, Nouara Lhocine, Alexandra Andrieux, Giulia Nigro, Joëlle Mounier, Philippe Sansonetti, Anne Dejean
Publikováno v:
eLife, Vol 6 (2017)
Disruption of the sumoylation/desumoylation equilibrium is associated with several disease states such as cancer and infections, however the mechanisms regulating the global SUMO balance remain poorly defined. Here, we show that infection by Shigella
Externí odkaz:
https://doaj.org/article/6d3352ef2a5a4b7cbdb31b4aafd0e698
Autor:
André Verdel, Edwige Col, Claire Vourc'h, Sabrina Fritah, Virginie Faure, Jessica Penin, Daphné Seigneurin-Berny, Solenne Dufour
Publikováno v:
Chromosoma
Chromosoma, 2021, 130 (1), pp.53-60. ⟨10.1007/s00412-021-00751-2⟩
Chromosoma, Springer Verlag, 2021, 130 (1), pp.53-60. ⟨10.1007/s00412-021-00751-2⟩
Chromosoma, 2021, 130 (1), pp.53-60. ⟨10.1007/s00412-021-00751-2⟩
Chromosoma, Springer Verlag, 2021, 130 (1), pp.53-60. ⟨10.1007/s00412-021-00751-2⟩
The heat shock factor 1 (HSF1)-dependent transcriptional activation of human pericentric heterochromatin in heat-shocked cells is the most striking example of transcriptional activation of heterochromatin. Until now, pericentric heterochromatin of ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b8e5563f177c46281420e54a586f02
https://doi.org/10.1007/s00412-021-00751-2
https://doi.org/10.1007/s00412-021-00751-2
Autor:
Wenjing Zhou, Hrvoje Miletic, Jian Wang, Sabrina Fritah, Mingzhi Han, Ning Yang, Shuai Wang, Frits Thorsen, Anjing Chen, Xu Wang, Rolf Bjerkvig, Xingang Li, Gang Li, Bin Huang, Shilei Ni
Publikováno v:
Brain
Long non-coding RNAs (lncRNAs) play critical roles in tumour progression. Han et al. report that the lncRNA MIR22HG promotes glioma progression by generating miR-22-3p and miR-22-5p, and show that targeting MIR22HG/miR-22 with a novel small molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca295c8413fcfb05e475c48c412e93b6
https://doi.org/10.1093/brain/awz406
https://doi.org/10.1093/brain/awz406
XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase
Autor:
Eric Van Dyck, Katrin Neumann, Thibaut Peterlini, Philippe Pasero, Barbara Klink, H. Erasimus, Simone P. Niclou, Lia Pinto, Christel Herold-Mende, Petr V. Nazarov, Diyavarshini Gopaul, Sabrina Fritah, Abhishek Sharma, Marie-Christine Caron, Patrick Calsou, Jean-Yves Masson, Sébastien Britton
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2021, 49 (17), pp.9906-9925. ⟨10.1093/nar/gkab785⟩
Nucleic Acids Research (NAR)
Nucleic Acids Research, Oxford University Press, 2021, 49 (17), pp.9906-9925. ⟨10.1093/nar/gkab785⟩
Nucleic Acids Research (NAR)
Replication-associated single-ended DNA double-strand breaks (seDSBs) are repaired predominantly through RAD51-mediated homologous recombination (HR). Removal of the non-homologous end-joining (NHEJ) factor Ku from resected seDSB ends is crucial for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a198846723c644dcea0d5d08cbfa5f
https://hal.archives-ouvertes.fr/hal-03371180
https://hal.archives-ouvertes.fr/hal-03371180
Autor:
H. Erasimus, Abhishek Sharma, Petr V. Nazarov, Barbara Klink, Sabrina Fritah, Lia Pinto, Jean-Yves Masson, Marie-Christine Caron, Christel Herold-Mende, Van Dyck E, Sébastien Britton, Katrin Neumann, Patrick Calsou, Simone P. Niclou
Unrepaired O6-methylguanine lesions induced by the alkylating chemotherapy agent temozolomide lead to replication-associated single-ended DNA double-strand breaks (seDSBs) that are repaired predominantly through RAD51-mediated homologous recombinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b077d4eb06873115fcb39866939467
https://hal.archives-ouvertes.fr/hal-02989098/document
https://hal.archives-ouvertes.fr/hal-02989098/document
Autor:
Francisco Azuaje, Tao Ye, Zhongming Zhao, Arnaud Muller, Wei Jiang, Ramkrishna Mitra, Monika Dieterle, Anna Golebiewska, Mohamad Sarmini, Eric Van Dyck, Christel Herold-Mende, Simone P. Niclou, Sabrina Fritah
Publikováno v:
Cancers
Cancers, 2020, 12 (9), pp.2583. ⟨10.3390/cancers12092583⟩
Cancers, Vol 12, Iss 2583, p 2583 (2020)
12:2853
Volume 12
Issue 9
Cancers, 2020, 12 (9), pp.2583. ⟨10.3390/cancers12092583⟩
Cancers, Vol 12, Iss 2583, p 2583 (2020)
12:2853
Volume 12
Issue 9
Simple Summary Glioblastoma (GBM) is the most aggressive brain tumor and most resistant to therapy. The identification of novel predictive biomarkers or targets to counteract chemoresistance, requires a better understanding of the GBM primary respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad9ad14c2168cbd1dd2b9c9011f3735
https://hal.science/hal-03669755
https://hal.science/hal-03669755