Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Sabrina, Ehnert"'
Autor:
Regina Breinbauer, Michelle Mäling, Sabrina Ehnert, Gunnar Blumenstock, Tobias Schwarz, Johann Jazewitsch, Felix Erne, Marie K. Reumann, Mika F. Rollmann, Benedikt J. Braun, Tina Histing, Andreas K. Nüssler
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Around 10% of fractures lead to complications. With increasing fracture incidences in recent years, this poses a serious burden on the healthcare system, with increasing costs for treatment. In the present study, we aimed to ident
Externí odkaz:
https://doaj.org/article/0b8b4234a0a249449936a2c0819e19d1
Autor:
Leyla Tümen, Lena Pollmann-Schweckhorst, Regina Breinbauer, Mohammad M. Hammour, Romina H. Aspera-Werz, Gunnar Blumenstock, Tina Histing, Maximilian M. Menger, Sabrina Ehnert, Andreas Nüssler
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 23, Pp 967-990 (2024)
Smoking is the most significant and modifiable risk factor for a range of conditions, including cancer, cardiovascular and respiratory diseases. Furthermore, it significantly reduces bone mass and increases the risk of fragility fractures due to its
Externí odkaz:
https://doaj.org/article/2a920180812540c68dceedca701b4eb3
Vitamin D3 deficiency and osteopenia in spastic paraplegia type 5 indicate impaired bone homeostasis
Autor:
Sabrina Ehnert, Stefan Hauser, Holger Hengel, Philip Höflinger, Rebecca Schüle, Tobias Lindig, Jonathan Baets, Tine Deconinck, Peter de Jonghe, Tina Histing, Andreas K. Nüssler, Ludger Schöls, Tim W. Rattay
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Hereditary spastic paraplegia type 5 (SPG5) is an autosomal recessively inherited movement disorder characterized by progressive spastic gait disturbance and afferent ataxia. SPG5 is caused by bi-allelic loss of function mutations in CYP7B1
Externí odkaz:
https://doaj.org/article/0838cc419332405ab3daed3ea2d41e47
Autor:
Philipp Hemmann, Lisa Kloppenburg, Regina Breinbauer, Sabrina Ehnert, Gunnar Blumenstock, Marie K. Reumann, Felix Erne, Johann Jazewitsch, Tobias Schwarz, Heiko Baumgartner, Tina Histing, Mika Rollmann, Andreas K. Nüssler
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 23, Pp 53-61 (2024)
Early and reliable detection of infection is vital for successful treatment. Serum markers such as C-reactive protein (CRP) and procalcitonin (PCT) are known to increase with a time lag. Azurocidin 1 (AZU1) has emerged as a promising marker for septi
Externí odkaz:
https://doaj.org/article/7bfe2ec364324a1183a12ddfc772964d
Autor:
Maximilian M. Menger, Michelle Bleimehl, David Bauer, Claudia Scheuer, Sandra Hans, Dominik Saul, Sabrina Ehnert, Michael D. Menger, Tina Histing, Matthias W. Laschke
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115697- (2023)
Non-unions represent a major complication in trauma and orthopedic surgery. Many factors contribute to bone regeneration, out of which an adequate vascularization has been recognized as crucial. The phosphodiesterase-3 (PDE-3) inhibitor cilostazol ha
Externí odkaz:
https://doaj.org/article/44ac4bd9003f47d9be9edff71c83440b
Autor:
Sabrina Ehnert, Anna J. Schreiner, Claudine Seeliger, Josef Ecker, Fabian Springer, Gerhard Liebisch, Philipp Hemmann, Tina Histing, Andreas K. Nussler
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 22, Pp 207-220 (2023)
There is general consent that with decreasing bone mineral density the amount of marrow adipose tissue increases. While image-based techniques, claim an increase in saturated fatty acids responsible for this effect, this study shows an increase in bo
Externí odkaz:
https://doaj.org/article/6efc02c67cab4868acc26176789e9ce0
Autor:
Maximilian M. Menger, Maximilian Stief, Claudia Scheuer, Mika F. Rollmann, Steven C. Herath, Benedikt J. Braun, Sabrina Ehnert, Andreas K. Nussler, Michael D. Menger, Matthias W. Laschke, Tina Histing
Publikováno v:
Experimental Gerontology, Vol 178, Iss , Pp 112201- (2023)
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as diclofenac, belong to the most prescribed analgesic medication after traumatic injuries. However, there is accumulating evidence that NSAIDs impair fracture healing. Because bone regeneration in
Externí odkaz:
https://doaj.org/article/382a6d9753f949d59f70bffa0c2c5f8c
Autor:
Maximilian M. Menger, Maximilian Emmerich, Claudia Scheuer, Sandra Hans, Sabrina Ehnert, Andreas K. Nüssler, Steven C. Herath, Konrad Steinestel, Michael D. Menger, Tina Histing, Matthias W. Laschke
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 755 (2024)
Fracture healing in the aged is associated with a reduced healing capacity, which often results in delayed healing or non-union formation. Many factors may contribute to this deterioration of bone regeneration, including a reduced ‘angiogenic traum
Externí odkaz:
https://doaj.org/article/db94a62842534c7da4737094bdf8b220
Autor:
Sabrina Ehnert, Tina Histing
Publikováno v:
Bioengineering, Vol 11, Iss 1, p 67 (2024)
Despite a constant refinement of surgical techniques and bone fixation methods, up to 15% of fractures result in impaired healing or even develop a non-union [...]
Externí odkaz:
https://doaj.org/article/6eeef3f768184e66952f9a23e7b7db48
Autor:
Tanja C. Maisenbacher, Sabrina Ehnert, Tina Histing, Andreas K. Nüssler, Maximilian M. Menger
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3302 (2023)
Diabetes represents a major risk factor for impaired fracture healing. Type 2 diabetes mellitus is a growing epidemic worldwide, hence an increase in diabetes-related complications in fracture healing can be expected. However, the underlying mechanis
Externí odkaz:
https://doaj.org/article/85340aaa19054bbda82588ed61af889c