Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sabra Djomehri"'
Autor:
Giuseppina Augimeri, Maria E. Gonzalez, Alessandro Paolì, Ahmad Eido, Yehyun Choi, Boris Burman, Sabra Djomehri, Santhosh Kumar Karthikeyan, Sooryanarayana Varambally, Johanna M. Buschhaus, Yu-Chih Chen, Loredana Mauro, Daniela Bonofiglio, Alexey I. Nesvizhskii, Gary D. Luker, Sebastiano Andò, Euisik Yoon, Celina G. Kleer
Publikováno v:
JCI Insight, Vol 8, Iss 18 (2023)
Patients with triple-negative breast cancer remain at risk for metastatic disease despite treatment. The acquisition of chemoresistance is a major cause of tumor relapse and death, but the mechanisms are far from understood. We have demonstrated that
Externí odkaz:
https://doaj.org/article/0fdb611aabcf4f8398eea1d60e3165be
Autor:
Kathryn Grandfield, Ralf-Peter Herber, Ling Chen, Sabra Djomehri, Caleb Tam, Ji-Hyun Lee, Evan Brown, Wood R. Woolwine III, Don Curtis, Mark Ryder, Jim Schuck, Samuel Webb, William Landis, Sunita P. Ho
Publikováno v:
Bone Reports, Vol 3, Iss C, Pp 20-31 (2015)
Objective: The objective of this study was to investigate the effect of mechanical strain by mapping physicochemical properties at periodontal ligament (PDL)–bone and PDL–cementum attachment sites and within the tissues per se. Design: Accentuate
Externí odkaz:
https://doaj.org/article/c7551be9362c42d79118f138d5394271
Autor:
Lorena Lazo de la Vega, Lisa A. Newman, Miguel L Rufail, Maria E. Gonzalez, Sabra Djomehri, Celina G. Kleer, Talha Anwar, Scott A. Tomlins
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
African and African-American (AA) women have higher incidence of triple-negative breast cancers (TNBC) with high histological grade and aggressive clinical behavior, but the reasons are not fully understood. We recently found that the oncogenic prote
Autor:
Sooryanarayana Varambally, Emily R McMullen, Stephanie L. Skala, Maria E. Gonzalez, Darshan S. Chandrashekar, Sabra Djomehri, Celina G. Kleer
Publikováno v:
Breast Cancer
BACKGROUND: Metaplastic carcinoma is an aggressive, triple-negative breast cancer (TNBC) with differentiation towards squamous, spindle, or mesenchymal cell types. The molecular underpinnings of the histological subtypes are unclear. Our lab discover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d626095245fca2bb786256c16d085d07
https://europepmc.org/articles/PMC7925348/
https://europepmc.org/articles/PMC7925348/
Autor:
Celina G. Kleer, Sabra Djomehri, Kathryn E. Luker, David Mertz, Gary D. Luker, Hao Chen Chang, Soojung Lee, Jason Sentosa, Eric Parigoris, Madeleine Turner, Shuichi Takayama, Amy Y. Liu
Publikováno v:
Adv Healthc Mater
This paper describes mammary organoids with a basal-in phenotype where the basement membrane is located on the interior surface of the organoid. A key materials consideration to induce this basal-in phenotype is the use of a minimal gel scaffold that
Autor:
Venkatesha Basrur, Celina G. Kleer, Shilpa R. Tekula, Sabra Djomehri, Ashley Cimino-Mathews, Maria E. Gonzalez, Marissa J. White, Alexey I. Nesvizhskii, Boris Burman, Pedram Argani, Hui Yin Chang, Felipe da Veiga Leprevost
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Metaplastic breast carcinoma (MBC) is a highly aggressive form of triple-negative cancer (TNBC), defined by the presence of metaplastic components of spindle, squamous, or sarcomatoid histology. The protein profiles underpinning the pathological subt
Autor:
Kelley M. Kidwell, Maria E. Gonzalez, Celina G. Kleer, Sabra Djomehri, Emily R McMullen, Stephanie L. Skala, Mai Tran, Dafydd G. Thomas, Boris Burman
Publikováno v:
Breast Cancer Research and Treatment. 172:577-586
Metaplastic breast carcinomas are an aggressive subtype of triple-negative breast cancer (TNBC) in which part or all of the adenocarcinoma transforms into a non-glandular component (e.g., spindled, squamous, or heterologous). We discovered that mamma
Autor:
Jim Schuck, Sunita P. Ho, Donald A. Curtis, Ling Chen, Evan Brown, Kathryn Grandfield, Sabra Djomehri, Ralf Peter Herber, Ji-Hyun Lee, Wood R. Woolwine Iii, Mark I. Ryder, Caleb. S. Tam, Samuel M. Webb, William J. Landis
Publikováno v:
Bone Reports, Vol 3, Iss C, Pp 20-31 (2015)
Bone Reports
Bone Reports
Objective The objective of this study was to investigate the effect of mechanical strain by mapping physicochemical properties at periodontal ligament (PDL)–bone and PDL–cementum attachment sites and within the tissues per se. Design Accentuated
Publikováno v:
Cancer Research. 80:981-981
Metaplastic breast carcinoma (MBC) is a rare subtype of triple negative breast carcinoma with frequent metastasis and poor response to chemotherapy. MBCs are defined by the presence of “metaplastic” components of spindle, squamous, or sarcomatoid
Publikováno v:
Journal of cell communication and signaling. 13(1)
While 3D cellular models are useful to study biological processes, gel-embedded organoids have large variability. This paper describes high-yield production of large (~1 mm diameter), scaffold-free, highly-spherical organoids in a one drop-one organo