Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sabita, Islam"'
Autor:
Jennifer P Morton, Matthew Wilson, Hannah Buckley, Alwin G Schuller, Richard Goodwin, Kate Williamson, Frances M Richards, Duncan I Jodrell, Saadia A Karim, Simon J Dovedi, Jim Eyles, Vincenzo Graziano, Andreas Dannhorn, Heather Hulme, Sheng Y Lee, Brajesh P Kaistha, Sabita Islam, James E D Thaventhiran, Rebecca Brais
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background The prognosis for patients with pancreatic ductal adenocarcinoma (PDAC) remains extremely poor. It has been suggested that the adenosine pathway contributes to the ability of PDAC to evade the immune system and hence, its resistance to imm
Externí odkaz:
https://doaj.org/article/f9d832bad08344709ee59ce32bb6e960
Autor:
Vincenzo Graziano, Andreas Dannhorn, Heather Hulme, Kate Williamson, Hannah Buckley, Saadia A Karim, Sheng Y. Lee, Brajesh P. Kaistha, Sabita Islam, James E. D. Thaventhiran, Frances M. Richards, Richard Goodwin, Rebecca Brais, Jennifer P Morton, Simon J. Dovedi, Alwin G. Schuller, Jim Eyles, Duncan I. Jodrell
The prognosis for patients with pancreatic ductal adenocarcinoma (PDAC) remains extremely poor. It has been suggested that the adenosine pathway contributes to the ability of PDAC to evade the immune system and its resistance to immunotherapies (Immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9ba2f978938a00c55c3b85f14977a18
https://doi.org/10.1101/2022.05.24.493238
https://doi.org/10.1101/2022.05.24.493238
Publikováno v:
Clinical and Experimental Allergy
Autor:
Katherine Anagnostou, Sabita Islam, Yvonne King, Loraine Foley, Laura Pasea, Chris Palmer, Simon Bond, Pamela Ewan, Andrew Clark
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 1, Iss 4 (2014)
Background: Peanut allergy is a common disease that causes severe and fatal food allergic reactions. Currently, the best treatment is avoidance as repeated reactions can occur. Quality of life (QoL) is reduced by fear of severe reactions and social l
Externí odkaz:
https://doaj.org/article/de6dd71935e845a09f95e1c67683039c
Autor:
Vincenzo Graziano, Andreas Dannhorn, Kate Williamson, Heather Hulme, Hannah Buckley, Sheng Y. Lee, Sabita Islam, James E. Thaventhiran, Richard Goodwin, Rebecca Brais, Simon J. Dovedi, Alwin Schuller, Jim Eyles, Duncan I. Jodrell
Publikováno v:
Cancer Research. 82:6103-6103
The prognosis for patients with pancreatic adenocarcinoma (PDAC) remains extremely poor. PDAC is resistant to both conventional therapies and emerging immunotherapies (IOT), apart from tumors with mismatch repair deficiency. This may be explained in
Autor:
Purity Bundi, Emma Dean, Jeff Evans, Bruno Henrique Rala De Paula, James Thaventhiran, Richard J. A. Goodwin, Maria Pawula, Tatiana Hernandez, Subha Anand, Josephine Khan, Duncan I. Jodrell, Adrian Mander, Simon Smith, Gonzalez-Lopes Alberto, Eva M. Serrao, Sabita Islam, Vincenzo Graziano, Godfrey Edmund, Bristi Basu
Publikováno v:
Cancer Research. 81:CT214-CT214
Background:ATRiUM is a phase 1 trial to assess the safety, tolerability, pharmacokinetics and preliminary antitumour activity of ascending doses of combined therapy with the ATR inhibitor ceralasertib AZD6738 and gemcitabine, Using a Model based desi
Autor:
Loraine Foley, John Deighton, Simon Bond, Sabita Islam, Pamela Ewan, Christopher R. Palmer, Laura Pasea, Katherine Anagnostou, Y. King, Andrew Clark
Publikováno v:
The Lancet. 383(9925):1297-1304
SummaryBackgroundSmall studies suggest peanut oral immunotherapy (OIT) might be effective in the treatment of peanut allergy. We aimed to establish the efficacy of OIT for the desensitisation of children with allergy to peanuts.MethodsWe did a random
Autor:
Pamela Ewan, Andrew Clark, Sabita Islam, Y. King, Katherine Anagnostou, John Deighton, S. Szun
Publikováno v:
Clinical & Experimental Allergy. 41:706-712
Summary Background Egg allergy is common and although resolution to uncooked egg has been demonstrated, there is lack of evidence to guide reintroduction of well-cooked egg. Objectives To examine the rate of resolution to well-cooked, compared with u
Publikováno v:
Clinical & Experimental Allergy. 41:1273-1281
Summary Background Peanut allergy is severe and rarely resolves. Objective To test the efficacy and safety of a new oral immunotherapy (OIT) protocol for peanut allergy. Method Twenty-two peanut-allergic children underwent oral challenge. OIT was adm
Publikováno v:
The Journal of Allergy and Clinical Immunology: In Practice. 6:1692-1698.e1
Serum tryptase is useful in diagnosing drug and venom anaphylaxis. Its utility in food anaphylaxis is unknown.The objective of this study was to determine whether tryptase rises in food allergic reactions, optimal sampling time points, and a diagnost