Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Sabirsh, A."'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/20f94cd58ce24bedb250d59916b512af
Autor:
Kai Liu, Ralf Nilsson, Elisa Lázaro-Ibáñez, Hanna Duàn, Tasso Miliotis, Marie Strimfors, Michael Lerche, Ana Rita Salgado Ribeiro, Johan Ulander, Daniel Lindén, Anna Salvati, Alan Sabirsh
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract In terms of lipid nanoparticle (LNP) engineering, the relationship between particle composition, delivery efficacy, and the composition of the biocoronas that form around LNPs, is poorly understood. To explore this we analyze naturally effic
Externí odkaz:
https://doaj.org/article/41ddf1ba8b124addb8c13982c9688b78
Autor:
Helgadottir, Saga, Midtvedt, Benjamin, Pineda, Jesús, Sabirsh, Alan, Adiels, Caroline B., Romeo, Stefano, Midtvedt, Daniel, Volpe, Giovanni
Quantitative analysis of cell structures is essential for biomedical and pharmaceutical research. The standard imaging approach relies on fluorescence microscopy, where cell structures of interest are labeled by chemical staining techniques. However,
Externí odkaz:
http://arxiv.org/abs/2012.12986
Autor:
Stein, Oliver, Blamey, Ben, Karlsson, Johan, Sabirsh, Alan, Spjuth, Ola, Hellander, Andreas, Toor, Salman
Data stream processing frameworks provide reliable and efficient mechanisms for executing complex workflows over large datasets. A common challenge for the majority of currently available streaming frameworks is efficient utilization of resources. Mo
Externí odkaz:
http://arxiv.org/abs/2001.10865
Autor:
Joubert, Fanny, Munson, Michael J., Sabirsh, Alan, England, Richard M., Hemmerling, Martin, Alexander, Cameron, Ashford, Marianne B.
Publikováno v:
In Journal of Controlled Release April 2023 356:580-594
Akademický článek
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Akademický článek
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Autor:
Ya Liu, Prof. Changhong Zhao, Dr. Alan Sabirsh, Dr. Lilei Ye, Dr. Xiaoqiu Wu, Prof. Hongbin Lu, Prof. Johan Liu
Publikováno v:
ChemistryOpen, Vol 10, Iss 7, Pp 666-671 (2021)
Abstract Abstract: During the last decades, there has been growing interest in using therapeutic messager RNA (mRNA) together with drug delivery systems. Naked, unformulated mRNA is, however, unable to cross the cell membrane and is susceptible to de
Externí odkaz:
https://doaj.org/article/33639fe3c64342f68efe46ebd1b689f0
Autor:
Blakney, Anna K., Deletic, Polina, McKay, Paul F., Bouton, Clément R., Ashford, Marianne, Shattock, Robin J., Sabirsh, Alan
Publikováno v:
In Journal of Controlled Release 10 February 2021 330:1250-1261
Autor:
Michael J. Munson, Gwen O’Driscoll, Andreia M. Silva, Elisa Lázaro-Ibáñez, Audrey Gallud, John T. Wilson, Anna Collén, Elin K. Esbjörner, Alan Sabirsh
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Munson et al. develop a high-throughput Galectin-9 reporter based endosomal escape imaging assay to probe correlations between nanoparticle-mediated uptake, endosomal escape frequency, and mRNA translation. By screening various delivery systems, modu
Externí odkaz:
https://doaj.org/article/6d71f1a55da4454e8e456d8390871e01