Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Sabino, Prencipe"'
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Akademický článek
Altered adipocyte differentiation and unbalanced autophagy in type 2 Familial Partial Lipodystrophy: an in vitro and in vivo study of adipose tissue browning
Autor: Camilla Pellegrini, Marta Columbaro, Elisa Schena, Sabino Prencipe, Davide Andrenacci, Patricia Iozzo, Maria Angela Guzzardi, Cristina Capanni, Elisabetta Mattioli, Manuela Loi, David Araujo-Vilar, Stefano Squarzoni, Saverio Cinti, Paolo Morselli, Assuero Giorgetti, Laura Zanotti, Alessandra Gambineri, Giovanna Lattanzi
Publikováno v: Experimental and Molecular Medicine, Vol 51, Iss 8, Pp 1-17 (2019)
Fat tissue disorders: Dysfunctional fat cell differentiation An abnormal distribution of fatty tissues associated with certain tissue disorders is driven by disrupted fat cell differentiation. Type 2 familial partial lipodystrophy (FPLD2) is a geneti
Externí odkaz: https://doaj.org/article/acb5e923c2674727aca3ca4769ad4e1d
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3
Altered modulation of lamin A/C-HDAC2 interaction and p21 expression during oxidative stress response in HGPS
Autor: Davide Gentilini, Giovanna Lattanzi, Sergio Valente, Daniel Remondini, Anna Maria Di Blasio, Emanuela Scarano, Elisabetta Mattioli, Antonello Mai, Davide Andrenacci, Katia Scotlandi, Giulia Piaggio, Sabino Prencipe, Cecilia Garofalo, Lucia Cicchilitti
Publikováno v: Aging Cell
Defects in stress response are main determinants of cellular senescence and organism aging. In fibroblasts from patients affected by Hutchinson–Gilford progeria, a severe LMNA‐linked syndrome associated with bone resorption, cardiovascular disord
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62bceaee753399cd4eefc2ee077e234f
http://hdl.handle.net/11585/663880
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4
Modulation of TGFbeta 2 levels by lamin A in U2-OS osteoblast-like cells: Understanding the osteolytic process triggered by altered lamins
Autor: Cristina Cappelletti, Paolo Sbraccia, Stefano Squarzoni, Paola Cavalcante, Nicola Baldini, Sofia Avnet, Giuseppe Novelli, Sabino Prencipe, Alberto M. Martelli, Maria Rosaria D'Apice, Giovanna Lattanzi, Pia Bernasconi, Camilla Evangelisti, Silvia Lemma
Publikováno v: Scopus-Elsevier
Europe PubMed Central
Oncotarget
Transforming growth factor beta (TGFbeta) plays an essential role in bone homeostasis and deregulation of TGFbeta occurs in bone pathologies. Patients affected by Mandibuloacral Dysplasia (MADA), a progeroid disease linked to LMNA mutations, suffer f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578b27849e9d0b7b4cc30f00b60bcc55
http://hdl.handle.net/2108/244453
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5
Lamins are rapamycin targets that impact human longevity: a study in centenarians
Autor: Giovanna, Lattanzi, Michela, Ortolani, Marta, Columbaro, Sabino, Prencipe, Elisabetta, Mattioli, Catia, Lanzarini, Nadir M, Maraldi, Vittoria, Cenni, Paolo, Garagnani, Stefano, Salvioli, Gianluca, Storci, Massimiliano, Bonafè, Cristina, Capanni, Claudio, Franceschi
Publikováno v: Journal of Cell Science; Vol 127
The dynamic organisation of the cell nucleus is profoundly modified during growth, development and senescence as a result of changes in chromatin arrangement and gene transcription. A plethora of data suggests that the nuclear lamina is a key player
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::25420e77c82f46e8e59fb42b8e183e45
http://hdl.handle.net/11585/250536
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6
Centenarian lamins: rapamycin targets in longevity
Autor: Paolo Garagnani, Gianluca Storci, Stefano Salvioli, Giovanna Lattanzi, Marta Columbaro, Michela Ortolani, Nadir M. Maraldi, Elisabetta Mattioli, Vittoria Cenni, Massimiliano Bonafè, Cristina Capanni, Claudio Franceschi, Catia Lanzarini, Sabino Prencipe
Publikováno v: Journal of Cell Science.
The dynamic organisation of the cell nucleus is profoundly modified during growth, development and senescence as a result of changes in chromatin arrangement and gene transcription. A plethora of data suggests that the nuclear lamina is a key player
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::561e78c28f8624e4d3a2961f7dd52514
https://doi.org/10.1242/jcs.133983
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7
Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria
Autor: Stefano Squarzoni, Michela Ortolani, Giovanna Lattanzi, N.M. Maraldi, Cristina Capanni, Sandra Marmiroli, Maria Rosaria D'Apice, Giuseppe Novelli, Vittoria Cenni, Sabino Prencipe, Emanuela Scarano, Milena Fini, Marta Columbaro
Publikováno v: European Journal of Histochemistry, Vol 55, Iss 4, Pp e36-e36 (2011)
European Journal of Histochemistry : EJH
Farnesylated prelamin A is a processing intermediate produced in the lamin A maturation pathway. Accumulation of a truncated farnesylated prelamin A form, called progerin, is a hallmark of the severe premature ageing syndrome, Hutchinson-Gilford prog
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1dbeb23f8d811cadda39b320cfe7ad
http://www.ejh.it/index.php/ejh/article/view/1895
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