Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Sabine Wrenger"'
Autor:
Friedemann R. Börner, Urszula Lechowicz, Sabine Wrenger, Beatriz Martinez-Delgado, Beata Olejnicka, Tobias Welte, Joanna Chorostowska-Wynimko, Michael Kiehntopf, Sabina Janciauskiene
Publikováno v:
ERJ Open Research, Vol 9, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/117cc48c4b524340b17a7f8665722819
Autor:
Julia Beimdiek, Sabina Janciauskiene, Sabine Wrenger, Sonja Volland, Adriana Rozy, Jan Fuge, Beata Olejnicka, Isabell Pink, Thomas Illig, Alexander Popov, Joanna Chorostowska, Falk F. R. Buettner, Tobias Welte
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background SARS-CoV-2 infected patients show heterogeneous clinical presentations ranging from mild symptoms to severe respiratory failure and death. Consequently, various markers reflect this wide spectrum of disease presentations. Methods
Externí odkaz:
https://doaj.org/article/15e691f1a242452fa7cc0b2bc025ec12
Autor:
Kokilavani Sivaraman, Paco Pino, Guillaume Raussin, Stephanie Anchisi, Charles Metayer, Nicolas Dagany, Julia Held, Sabine Wrenger, Tobias Welte, Maria J. Wurm, Florian M. Wurm, Beata Olejnicka, Sabina Janciauskiene
Publikováno v:
Microorganisms, Vol 11, Iss 11, p 2683 (2023)
Intracellular lipid droplets (LDs) can accumulate in response to inflammation, metabolic stresses, and other physiological/pathological processes. Herein, we investigated whether spike proteins of SARS-CoV-2 induce LDs in human peripheral blood monon
Externí odkaz:
https://doaj.org/article/db2413774549499d9f185926ebfc3649
Autor:
Tomoyuki Nakagiri, Sabine Wrenger, Kokilavani Sivaraman, Fabio Ius, Tobias Goecke, Patrick Zardo, Veronika Grau, Tobias Welte, Axel Haverich, Ann-Kathrin Knöfel, Sabina Janciauskiene
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background α1-Antitrypsin (AAT) is an acute phase glycoprotein, a multifunctional protein with proteinase inhibitory, anti-inflammatory and cytoprotective properties. Both preclinical and clinical experiences show that the therapy with plas
Externí odkaz:
https://doaj.org/article/81338e3554414e0a80aaf3bb0be142c3
Autor:
Jan C. Kamp, Naomi N. Kappe, Carlos Fernández Moro, Jan Fuge, Mark P. Kuehnel, Sabine Wrenger, Tobias Welte, Bart van Hoek, Danny D. Jonigk, Padmini P. S. J. Khedoe, Pavel Strnad, Mikael Björnstedt, Jan Stolk, Sabina Janciauskiene, Antal Nemeth
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2485 (2023)
PiZZ (Glu342Lys) α1-antitrypsin deficiency (AATD) is characterized by intrahepatic AAT polymerization and is a risk factor for liver disease development in children. The majority of PiZZ children are disease free, hence this mutation alone is not su
Externí odkaz:
https://doaj.org/article/fb5fa1378f564aad8da606ca073c7635
Autor:
Marc A. Schneider, Adriana Rozy, Sabine Wrenger, Petros Christopoulos, Thomas Muley, Michael Thomas, Michael Meister, Tobias Welte, Joanna Chorostowska-Wynimko, Sabina Janciauskiene
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
In the last decade, targeting the immune system became a promising therapy in advanced lung cancer stages. However, in a clinical follow-up, patient responses to immune checkpoint inhibitors widely differ. Peripheral blood is a minimally invasive sou
Externí odkaz:
https://doaj.org/article/c96dac0be66947dd807afa7c34ce65ce
Autor:
Natalie Schwarz, Srinu Tumpara, Sabine Wrenger, Evrim Ercetin, Jürg Hamacher, Tobias Welte, Sabina Janciauskiene
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Elevated levels of plasma alpha1-antitrypsin (AAT) correlate with a poor prognosis of various cancers. Herein, we investigated effects of exogenous AAT on non-small lung cancer cell lines with high (H1975) and very low (H661) baseline expres
Externí odkaz:
https://doaj.org/article/8b7d2f4e35ab458e8b9d5642d0b16ac7
Autor:
Anna Ricarda Gründing, Marc A. Schneider, Sarah Richtmann, Mark Kriegsmann, Hauke Winter, Beatriz Martinez-Delgado, Sarai Varona, Bin Liu, David S. DeLuca, Julia Held, Sabine Wrenger, Thomas Muley, Michael Meister, Tobias Welte, Sabina Janciauskiene
Publikováno v:
Cancers, Vol 14, Iss 18, p 4454 (2022)
To explore the relationship between cancer cell SREBF1 expression, lipid droplets (LDs) formation, and the sensitivity to chemotherapies, we cultured lung adenocarcinoma cells H1299 (with LD) and H1563 (without LD) in a serum-free basal medium (BM) o
Externí odkaz:
https://doaj.org/article/f852546b8ad847888c1b59c978aceee7
Autor:
Sri Harsha Meghadri, Beatriz Martinez-Delgado, Lena Ostermann, Gema Gomez-Mariano, Sara Perez-Luz, Srinu Tumpara, Sabine Wrenger, David S. DeLuca, Ulrich A. Maus, Tobias Welte, Sabina Janciauskiene
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10425 (2022)
The SERPINA1 gene encodes alpha1-antitrypsin (AAT), an acute phase glycoprotein and serine protease inhibitor that is mainly (80–90%) produced in the liver. Point mutations in the SERPINA1 gene can lead to the misfolding, intracellular accumulation
Externí odkaz:
https://doaj.org/article/48d305f6a2924b23942ec8d212f89cd8
Autor:
Srinu Tumpara, Matthias Ballmaier, Sabine Wrenger, Mandy König, Matthias Lehmann, Ralf Lichtinghagen, Beatriz Martinez-Delgado, Elena Korenbaum, David DeLuca, Nils Jedicke, Tobias Welte, Malin Fromme, Pavel Strnad, Jan Stolk, Sabina Janciauskiene
Publikováno v:
eLife, Vol 10 (2021)
Expression levels of CX3CR1 (C-X3-C motif chemokine receptor 1) on immune cells have significant importance in maintaining tissue homeostasis under physiological and pathological conditions. The factors implicated in the regulation of CX3CR1 and its
Externí odkaz:
https://doaj.org/article/6bbbe2d057b14eb88142e880aeb3a6e6