Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sabine Woetzel"'
Autor:
Laurent Brault, Rebekka Grundler, Vanda Pogacic, Juerg Schwaller, Justus Duyster, G. Berridge, Christelle Gasser, Antonello Villa, Christine Dierks, Stefan Knapp, Tobias Dechow, Sabine Woetzel, Anke Spoo, Andrea Biondi, Alex N. Bullock, Sabine Ehret
Publikováno v:
The Journal of Experimental Medicine
FLT3-ITD–mediated leukemogenesis is associated with increased expression of oncogenic PIM serine/threonine kinases. To dissect their role in FLT3-ITD–mediated transformation, we performed bone marrow reconstitution assays. Unexpectedly, FLT3-ITD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d43b6e0eb2aef17a5b7dc88a50d2fa
http://hdl.handle.net/10281/18542
http://hdl.handle.net/10281/18542
Autor:
Rebekka Grundler, Anke Spoo, Alec Bullock, Laurent Brault, Sabine Woetzel, Sabine Ehret, Tobias Dechow, Stefan Knapp, Martjin Nawijn, Andrea Biondi, Juerg Schwaller, Justus Duyster, G. Berridge, Christelle Gasser, Christine Dierks
Publikováno v:
BLOOD. 112(11)
Previous work has shown that FLT3-ITD mediated leukemogenesis is associated with increased expression of PIM1 and PIM2 serine/threonine kinases. Here we show that retroviral expression of FLT3-ITD could not compensate impaired clonogenic in vitro gro