Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sabine W. Baumann"'
Publikováno v:
Journal of Biological Chemistry. 277:46020-46025
The major isoform of the gamma-aminobutyric acid type A (GABA(A)) receptor is thought to be composed of 2alpha(1), 2beta(2), and 1gamma(2) subunit(s), which surround the ion pore. Definite evidence for the subunit arrangement is lacking. We show here
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 23(35)
The members of the pentameric ligand-gated receptor channel family are involved in information transfer in synapses and the neuromuscular junction. They often contain several copies of the same subunit isoform. Here, we present a method to functional
Publikováno v:
The Journal of biological chemistry. 277(48)
The major isoform of the gamma-aminobutyric acid type A (GABA(A)) receptor is thought to be composed of 2alpha(1), 2beta(2), and 1gamma(2) subunit(s), which surround the ion pore. Definite evidence for the subunit arrangement is lacking. We show here
Publikováno v:
The Journal of biological chemistry. 276(39)
The GABA(A) receptors are ligand-gated chloride channels. The subunit stoichiometry of the receptors is controversial; four, five, or six subunits per receptor molecule have been proposed for alphabeta receptors, whereas alphabetagamma receptors are
Publikováno v:
The Journal of biological chemistry. 276(28)
gamma-Aminobutyric acid type A (GABA(A)) receptors were immunopurified from bovine brain using a monoclonal antibody directed against the alpha1 subunit. Of the several proteins that copurified, a 34-kDa protein was analyzed further. After enrichment