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Autor:
Allan Gordon, Ira D. Goldfine, Julie M. Roessig, Kirk W. Johnson, Paul Rubin, Sabine Vukelich, Ann Neale, Padma Bezwada
Publikováno v:
The Journal of clinical endocrinology and metabolism. 102(8)
Background XOMA 358 (X358) is a fully human monoclonal antibody to the insulin receptor that acts as a negative allosteric modulator of insulin signaling. It is being developed as a novel treatment of hyperinsulinemic hypoglycemia. This report descri