Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Sabine Von Kleist"'
Publikováno v:
Acta Pathologica Microbiologica Scandinavica Series A :Pathology. :471-476
The presence of Tissue Polypeptide Antigen (TPA) and Carcino-embryonic Antigen (CEA) in serial sections of 32 breast carcinomas and one case of neurofibrosarcoma was demonstrated by immunocytochemistry using the indirect peroxidase technique. The neu
Publikováno v:
International Journal of Cancer. 78:533-538
Natural killer (NK) cells have been subdivided according to their CD16/CD56 expression into at least 2 subgroups. We examined the distribution of these NK subgroups in humans. In the blood of normal individuals, CD16++/CD56+/CD3- NK cells predominate
Publikováno v:
European Journal of Immunology. 28:3664-3674
The biliary glycoproteins (BGP or CD66a), a group of different splice variants of a single gene, are members of the carcinoembryonic antigen family and the immunoglobulin superfamily. Recently, we detected CD66a on IL-2 activated lymphocytes. In this
Publikováno v:
International Journal of Cancer. 72:142-148
We investigated the in vitro effects of factors secreted by 3 freshly explanted human colorectal-carcinoma (CRC) cell lines on lymphocyte proliferation, IL-2-receptor expression, LAK-cell generation and cytokine secretion. We found that the supernata
Autor:
Robert Kammerer, Sabine von Kleist
Publikováno v:
International Journal of Cancer. 68:457-463
We and others have shown that the carcinoembryonic antigen (CEA) modulates the susceptibility of human colorectal carcinoma cells to cytotoxic lymphocytes. We now demonstrate that the density of the CEA molecules on the tumor cell surface has a deter
Autor:
Fritz Grunert, Sabine von Kleist, G.A. Nagel, Michael R. Price, John A. Thompson, Peter Jantscheff, M. J. Embleton
Publikováno v:
Journal of Leukocyte Biology. 59:891-901
Antibodies to CD66 recognize at least five members (CD66a–e) of the carcinoembryonic antigen (CEA) family. Recombinant human single-chain Fv fragments (scFvs) that bind specifically to CD66a (biliary glycoprotein) were obtained from a naive human s
Publikováno v:
International Journal of Cancer. 65:740-745
Human T and natural-killer(NK) cells, that are thought to be the major cytotoxic effector-cell populations in the defence against neoplastic cells, were isolated from blood and decidua in order to analyze their expression of carcinoembronic-antigen-(
Publikováno v:
International Journal of Cancer. 63:349-355
Non-specific cross-reacting antigens (NCA-95 = CD66b and NCA-50/90 = CD66c) are members of the CEA (carcinoembryonic antigen = CD66e) family. Analysis of mRNA levels of CD66c in colon tumors suggests that this antigen is strongly up-regulated compare
Autor:
Ursula Elsässer-Beile, Carola Schurhammer-Fuhrmann, Jürgen Schulte Mönting, Harald Gallati, Wilfried Stähle, Sabine von Kleist
Publikováno v:
Cancer. 71:231-236
For the determination of cellular immunity status, mitogen-induced lymphocyte proliferation tests are used, along with measurements of cytokine secretion. The authors have established a test system with whole blood cell cultures in which they measure
Publikováno v:
International Journal of Immunopathology and Pharmacology. 5:185-191
The production of the cytokines IFN-gamma, IL-2, IL-1-alpha and TNF-alpha was investigated in the supernatants of mitogen-stimulated whole blood cell cultures from 52 oral contraceptive users, 33 pregnant women and 75 female controls. Cells from wome