Characterization of TCR-induced phosphorylation of PKCθ in primary murine lymphocytes

Autor: Sabine Thébault, Jorge Ochoa-Garay

Publikováno v: Molecular Immunology. 40:931-942

Protein kinase C theta (PKCtheta) is a member of the "novel" PKC subfamily which plays a critical role in T-cell activation. Following T-cell stimulation, PKCtheta translocates to the center of the immunological synapse where it co-localizes with the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc70dc75bcce779de71c58d3e898256
https://doi.org/10.1016/j.molimm.2003.10.014

Activation of E2F-mediated Transcription by Human T-cell Leukemia Virus Type I Tax Protein in a p16 -negative T-cell Line

Autor: Christian Devaux, Sabine Thébault, Isabelle Lemasson, Claude Sardet, Jean-Michel Mesnard

Publikováno v: Journal of Biological Chemistry. 273:23598-23604

The human T-cell leukemia virus type I (HTLV-I) is a causative agent of adult T-cell leukemia. Although the exact mechanism by which HTLV-I contributes to leukemogenesis is still unclear, the Tax protein is thought to play a major role in this proces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9d034ce72b46f78ad89bab8ff18f7e9
https://doi.org/10.1074/jbc.273.36.23598

Nuclear localization of HTLV-I bZIP factor (HBZ) is mediated by three distinct motifs

Autor: Patrick Hivin, Mélissa Frédéric, Charlotte Arpin-André, Jihane Basbous, Bernard Gay, Sabine Thébault, Jean-Michel Mesnard

Publikováno v: Journal of Cell Science, 118, Pt 7, pp. 1355-62
Journal of Cell Science, 118, 1355-62
Journal of Cell Science
Journal of Cell Science, 2005, 118 (Pt 7), pp.1355-62. ⟨10.1242/jcs.01727⟩
Journal of Cell Science, Company of Biologists, 2005, 118 (Pt 7), pp.1355-62. ⟨10.1242/jcs.01727⟩

Contains fulltext : 48999thebault.pdf (Publisher’s version ) (Open Access) The genome of the human T-cell leukemia virus type I (HTLV-I) codes for a basic leucine zipper protein, HBZ, capable of repressing JUN activity and viral transcription. Tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45dc4214f9454431af028181f9d17ac
https://pubmed.ncbi.nlm.nih.gov/15755797

The cAMP response element binding protein-2 (CREB-2) can interact with the C/EBP-homologous protein (CHOP)

Autor: Jean-Michel Mesnard, Joseph Aman Koffi, Sabine Thébault, Jihane Basbous, Frédéric Gachon, Christian Devaux, Gilles Gaudray

Publikováno v: FEBS Letters
FEBS Letters, Wiley, 2001, 502 (1-2), pp.57-62. ⟨10.1016/s0014-5793(01)02646-1⟩

cAMP response element binding protein-2 (CREB-2) is a basic leucine zipper (bZIP) factor that was originally described as a repressor of CRE-dependent transcription but that can also act as a transcriptional activator. Moreover, CREB-2 is able to fun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3836c39742818e924ab7cf080adbde02
https://hal.archives-ouvertes.fr/hal-02376693

CREB-2, a cellular CRE-dependent transcription repressor, functions in association with Tax as an activator of the human T-cell leukemia virus type 1 promoter

Autor: Frédéric Gachon, Sabine Thébault, Annick Peleraux, Isabelle Lemasson, Christian Devaux, Joelle Dick, Jean-Michel Mesnard

Publikováno v: Journal of Virology, vol. 72, no. 10, pp. 8332-8337
Scopus-Elsevier

The Tax protein of the human T-cell leukemia virus type 1 (HTLV-1) has been implicated in human T-cell immortalization. The primary function of Tax is to transcriptionally activate the HTLV-1 promoter, but Tax is also known to stimulate expression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a22bbcbff166c431f1926027afb891
https://serval.unil.ch/resource/serval:BIB_4DA4C34C6319.P001/REF.pdf