Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sabine Telemaque"'
Autor:
Sabine Telemaque, James D. Marsh, Terrie Grain, Nancy J. Rusch, Sung W. Rhee, Swapnil K. Sonkusare, Joseph R. Stimers
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 325:37-46
Calcium influx through long-lasting ("L-type") Ca(2+) channels (Ca(V)) drives excitation-contraction in the normal heart. Dysregulation of this process contributes to Ca(2+) overload, and interventions that reduce expression of the pore-forming alpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f3dcffa8d0f32e2f811688a7c63d87
https://doi.org/10.1124/jpet.107.128215
https://doi.org/10.1124/jpet.107.128215
Autor:
Aleksandra Pesic, Philip Palade, Swapnil K. Sonkusare, Nancy J. Rusch, Sabine Telemaque, James D. Marsh
Publikováno v:
Vascular Pharmacology. 44:131-142
Long-lasting Ca(2+) (Ca(L)) channels of the Ca(v)1.2 gene family are heteromultimeric structures that are minimally composed of a pore-forming alpha(1C) subunit and regulatory beta and alpha(2)delta subunits in vascular smooth muscle cells. The Ca(L)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9fa843d602b2345d2a16f4a60e87e8c
https://doi.org/10.1016/j.vph.2005.10.005
https://doi.org/10.1016/j.vph.2005.10.005
Autor:
Remus M. Berretta, David M. Harris, Sabine Telemaque Potts, Geoffrey Mills, Hajime Kubo, Jed Moyer, Steven R. Houser, Xiongwen Chen, James D. Marsh, Xiaoying Zhang
Publikováno v:
Circulation Research. 97:1009-1017
Increases in Ca 2+ influx through the L-type Ca 2+ channel (LTCC, Cav1.2) augment sarcoplasmic reticulum (SR) Ca 2+ loading and the amplitude of the cytosolic Ca 2+ transient to enhance cardiac myocyte contractility. Our hypothesis is that persistent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e36d92fc5feb6ac800f488981da26581
https://doi.org/10.1161/01.res.0000189270.72915.d1
https://doi.org/10.1161/01.res.0000189270.72915.d1
Publikováno v:
Diabetes. 48:2022-2027
The balance between hepatic glucose uptake and production is perturbed in both major forms of diabetes. It has been suggested that pharmacologic or genetic methods for enhancing glucokinase (GK) enzymatic activity in liver might be a means of increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372e10148a8f840f2130bcec2b20c139
https://doi.org/10.2337/diabetes.48.10.2022
https://doi.org/10.2337/diabetes.48.10.2022
Autor:
Sabine Telemaque, Meeiyueh Liu, Jonathan A. Dranoff, James D. Marsh, Shawn E Flynn, Terrie Singleton, Michel Fausther
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a173d18f30ec09a81465491061bdabc
https://doi.org/10.1096/fasebj.26.1_supplement.lb638
https://doi.org/10.1096/fasebj.26.1_supplement.lb638
Publikováno v:
The FASEB Journal. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0abeacf49e0cf38533be870bdd143b1b
https://doi.org/10.1096/fasebj.25.1_supplement.1026.14
https://doi.org/10.1096/fasebj.25.1_supplement.1026.14
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21da622801ff5a2b1b048fef6c2c5c62
https://doi.org/10.1096/fasebj.24.1_supplement.712.1
https://doi.org/10.1096/fasebj.24.1_supplement.712.1
Autor:
Meeiyueh Liu, K Brad Meredith, Amy J. Davidoff, James D. Marsh, Sabine Telemaque, Shawn E Flynn
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b17049026d7c462514027b9454f4fa5
https://doi.org/10.1096/fasebj.24.1_supplement.603.9
https://doi.org/10.1096/fasebj.24.1_supplement.603.9
Autor:
James D. Marsh, Sabine Telemaque
Publikováno v:
Expert review of cardiovascular therapy. 7(8)
Delivery of genes to the heart and vasculature for therapeutic purposes is an exciting strategy that is approaching clinical reality. Abnormalities of expression or function of ion channels is central to many cardiovascular diseases and gene delivery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2023a038eb0977e6ebeb3509014a3b19
https://pubmed.ncbi.nlm.nih.gov/19673672
https://pubmed.ncbi.nlm.nih.gov/19673672
Publikováno v:
Transactions of the American Clinical and Climatological Association. 119
Modifying ion channel expression and function in the heart and vasculature are potentially useful, novel approaches to managing cardiac hypertrophy, atrial fibrillation and hypertension. Calcium channels play a pivotal role in the heart and vasculatu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::106898e381247215cb1f51b3ab93d9be
https://pubmed.ncbi.nlm.nih.gov/18596857
https://pubmed.ncbi.nlm.nih.gov/18596857