Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Sabine Spijker"'
Autor:
Wouter R. Cox, Leonidas Faliagkas, Amber Besseling, Rolinka J. van der Loo, Sabine Spijker, Merel Kindt, Priyanka Rao-Ruiz
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Post-reactivation amnesia of contextual fear memories by blockade of noradrenergic signaling has been shown to have limited replicability in rodents. This is usually attributed to several boundary conditions that gate the destabilization of memory du
Externí odkaz:
https://doaj.org/article/1fdf726031084cde95eaae346108c75a
Autor:
Ioannis Kramvis, Rhodé van Westen, Hanna C. A. Lammertse, Danai Riga, Tim S. Heistek, Alex Loebel, Sabine Spijker, Huibert D. Mansvelder, Rhiannon M. Meredith
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Changes in excitation and inhibition are associated with the pathobiology of neurodevelopmental disorders of intellectual disability and autism and are widely described in Fragile X syndrome (FXS). In the prefrontal cortex (PFC), essential for cognit
Externí odkaz:
https://doaj.org/article/693380dca7b24a30a1210680191262f2
Autor:
Demirhan Çetereisi, Ioannis Kramvis, Titia Gebuis, Rolinka J. van der Loo, Yvonne Gouwenberg, Huibert D. Mansvelder, Ka Wan Li, August B. Smit, Sabine Spijker
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
G-protein-coupled receptor 158 (Gpr158) is highly expressed in striatum, hippocampus and prefrontal cortex. It gained attention as it was implicated in physiological responses to stress and depression. Recently, Gpr158 has been shown to act as a path
Externí odkaz:
https://doaj.org/article/761fd41b986740c9aee04bae5df5c6b4
Autor:
Remco V. Klaassen, Jasper Stroeder, Françoise Coussen, Anne-Sophie Hafner, Jennifer D. Petersen, Cedric Renancio, Leanne J. M. Schmitz, Elisabeth Normand, Johannes C. Lodder, Diana C. Rotaru, Priyanka Rao-Ruiz, Sabine Spijker, Huibert D. Mansvelder, Daniel Choquet, August B. Smit
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Auxiliary AMPA receptor subunits can affect gating and surface mobility. Here the authors show that Shisa6 traps AMPA receptors at postsynaptic sites via PSD-95, and keeps them in an activated state in the presence of glutamate, preventing full desen
Externí odkaz:
https://doaj.org/article/3618aa11f0194d7bb076e4d881df1108
Publikováno v:
Cells, Vol 9, Iss 9, p 2119 (2020)
Myelination greatly increases the speed of action potential propagation of neurons, thereby enhancing the efficacy of inter-neuronal communication and hence, potentially, optimizing the brain’s signal processing capability. The impact of genetic va
Externí odkaz:
https://doaj.org/article/fc295e05949f45b7af8395c4829284d2
Autor:
Leanne J M Schmitz, Remco V Klaassen, Marta Ruiperez-Alonso, Azra Elia Zamri, Jasper Stroeder, Priyanka Rao-Ruiz, Johannes C Lodder, Rolinka J van der Loo, Huib D Mansvelder, August B Smit, Sabine Spijker
Publikováno v:
eLife, Vol 7 (2018)
Externí odkaz:
https://doaj.org/article/3e5fa43f5e304aa39d288544cf3af078
Autor:
Leanne J M Schmitz, Remco V Klaassen, Marta Ruiperez-Alonso, Azra Elia Zamri, Jasper Stroeder, Priyanka Rao-Ruiz, Johannes C Lodder, Rolinka J van der Loo, Huib D Mansvelder, August B Smit, Sabine Spijker
Publikováno v:
eLife, Vol 6 (2017)
Glutamatergic synapses rely on AMPA receptors (AMPARs) for fast synaptic transmission and plasticity. AMPAR auxiliary proteins regulate receptor trafficking, and modulate receptor mobility and its biophysical properties. The AMPAR auxiliary protein S
Externí odkaz:
https://doaj.org/article/be9b9dbbc0344e15b25b3806a40e8a24
Autor:
Anna R Karataeva, Remco V Klaassen, Jasper Ströder, Marta Ruiperez-Alonso, Johannes J J Hjorth, Pim van Nierop, Sabine Spijker, Huibert D Mansvelder, August B Smit
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87360 (2014)
Shisa9 (initially named CKAMP44) has been identified as auxiliary subunit of the AMPA-type glutamate receptors and was shown to modulate its physiological properties. Shisa9 is a type-I transmembrane protein and contains a C-terminal PDZ domain that
Externí odkaz:
https://doaj.org/article/3399303962a3439baf30195c72cbbe0c
Autor:
Rick Jansen, Jaap Timmerman, Maarten Loos, Sabine Spijker, Arjen van Ooyen, Arjen B Brussaard, Huibert D Mansvelder, Neuro-Bsik Mouse Phenomics Consortium, August B Smit, Mathisca de Gunst, Klaus Linkenkaer-Hansen
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26586 (2011)
The hippocampus is critical for a wide range of emotional and cognitive behaviors. Here, we performed the first genome-wide search for genes influencing hippocampal oscillations. We measured local field potentials (LFPs) using 64-channel multi-electr
Externí odkaz:
https://doaj.org/article/aad73a10a2394f60aec19bb2d976568a
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 4 (2010)
Cognitive ability and the properties of brain oscillation are highly heritable in humans. Genetic variation underlying oscillatory activity might give rise to differences in cognition and behavior. How genetic diversity translates into altered proper
Externí odkaz:
https://doaj.org/article/0e3bab7b95234833bd4ca3c04f1aa2f5