Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sabine Simecek"'
Publikováno v:
Diabetes. 45:1386-1395
Pretreatment of porcine aortic endothelial cells with high D-glucose results in enhanced endothelium-derived relaxing factor (EDRF) formation (39%) due to increased endothelial Ca2+ release (57%) and Ca2+ entry (97%) to bradykinin. This study was des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3d742d992f32690f1526f5cdbdb492
https://doi.org/10.2337/diab.45.10.1386
https://doi.org/10.2337/diab.45.10.1386
Autor:
T. C. Wascher, Günther Jürgens, Wolfgang F. Graier, Sabine Simecek, Gert M. Kostner, Karla Posch, Sabina Baumgartner-Parzer
Publikováno v:
Diabetes. 48(6)
Little is known about the mechanism(s) of endothelial dysfunction in diabetes. In this study, the effect of nonenzymatic glycated LDL, a phenomenon induced by elevated D-glucose levels associated with diabetes, on porcine aortic endothelial cells was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45f0a86380f57a1ee8d586bc92b2d99
https://pubmed.ncbi.nlm.nih.gov/10342824
https://pubmed.ncbi.nlm.nih.gov/10342824
Autor:
Bernhard G. Hoebel, Sabine Simecek, Thomas C. Wascher, Wolfgang F. Graier, Gert M. Kostner, Peter Dittrich
Publikováno v:
European journal of pharmacology. 322(1)
Very recently we proposed that hyperactivity of endothelial Ca 2+ /cGMP signaling under hyperglycemic conditions is due to superoxide anion (O 2 − ) release. The present study was designed to investigate changes in endothelial glutathione (GSH) lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c8e0b3f2f74a0a96b8e5b010bdd775
https://pubmed.ncbi.nlm.nih.gov/9088879
https://pubmed.ncbi.nlm.nih.gov/9088879
Publikováno v:
FEBS letters. 350(1)
The role of intracellular free Ca 2+ concentration ([Ca 2+ ] i in cellular regulation of endothelin-(ET-1) secretion was investigated in cultured porcine aortic endothelial cells of first passage. Intracellular Ca 2+ concentration were adjusted betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b50385168940e305ecba9b8212c133
https://pubmed.ncbi.nlm.nih.gov/8062919
https://pubmed.ncbi.nlm.nih.gov/8062919
Autor:
Hermann Toplak, Wolfgang F. Graier, Güunter J Krejs, Thomas C. Wascher, Sabine Simecek, Walter R. Kukovetz
Publikováno v:
Diabetes. 43(8)
Prolonged treatment of vascular endothelial cells with pathologically high D-glucose amplifies autacoid-induced Ca2+ mobilization and thus formation of nitric oxide. This study investigated the Ca2+ source for the change in endothelial Ca2+ response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f3977cfd0e3e7b1bafb7c05cf11a1d
https://pubmed.ncbi.nlm.nih.gov/8039606
https://pubmed.ncbi.nlm.nih.gov/8039606
Publikováno v:
Europe PubMed Central
1. We tested the hypothesis that agonist-stimulated Ca2+ entry, and thus formation of endothelium-derived nitric oxide (EDNO) in vascular endothelial cells, is related to activation of microsomal P450 mono-oxygenase (P450 MO) and the biosynthesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb5a44b80e66f5650a042b19ac7621a
http://europepmc.org/abstract/med/7536247
http://europepmc.org/abstract/med/7536247
