Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Sabine Seuter"'
Autor:
Timothy Warwick, Marcel H. Schulz, Stefan Günther, Ralf Gilsbach, Antonio Neme, Carsten Carlberg, Ralf P. Brandes, Sabine Seuter
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The transcription factor vitamin D receptor (VDR) is the high affinity nuclear target of the biologically active form of vitamin D3 (1,25(OH)2D3). In order to identify pure genomic transcriptional effects of 1,25(OH)2D3, we used VDR cistrome
Externí odkaz:
https://doaj.org/article/cba2a41fe96a4a9f9401576c24fe4ce7
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
The molecular basis of vitamin D signaling implies that the metabolite 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) of the secosteroid vitamin D3 activates the transcription factor vitamin D receptor (VDR), which in turn modulates the expression of hundr
Externí odkaz:
https://doaj.org/article/31511a755925424181b6810a8a1cf570
Autor:
Maja Vukić, Antonio Neme, Sabine Seuter, Noora Saksa, Vanessa D F de Mello, Tarja Nurmi, Matti Uusitupa, Tomi-Pekka Tuomainen, Jyrki K Virtanen, Carsten Carlberg
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124339 (2015)
Vitamin D3 has transcriptome- and genome-wide effects and activates, via the binding of its metabolite 1α,25-dihydroxyvitamin D3 to the transcription factor vitamin D receptor (VDR), several hundred target genes. Using samples from a 5-month vitamin
Externí odkaz:
https://doaj.org/article/5c8c317013c149c6b31d1da10d24d023
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e96184 (2014)
The vitamin D receptor (VDR) is a transcription factor that mediates the genomic effects of 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3). Genome-wide there are several thousand binding sites and hundreds of primary 1,25(OH)2D3 target genes, but their fun
Externí odkaz:
https://doaj.org/article/b12b6de9b61f49868197b0ab45d754d5
Autor:
Carsten Carlberg, Sabine Seuter, Vanessa D F de Mello, Ursula Schwab, Sari Voutilainen, Kari Pulkki, Tarja Nurmi, Jyrki Virtanen, Tomi-Pekka Tuomainen, Matti Uusitupa
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e71042 (2013)
Vitamin D deficiency has been associated with an increased risk of developing a number of diseases. Here we investigated samples from 71 pre-diabetic individuals of the VitDmet study, a 5-month high dose vitamin D3 intervention trial during Finnish w
Externí odkaz:
https://doaj.org/article/c1da7c84d4e946b2919a4548d3f93c58
Autor:
Marius, Kreiß, Julia H, Oberlis, Sabine, Seuter, Iris, Bischoff-Kont, Duran, Sürün, Dominique, Thomas, Tamara, Göbel, Tobias, Schmid, Olof, Rådmark, Ralf P, Brandes, Robert, Fürst, Ann-Kathrin, Häfner, Dieter, Steinhilber
Publikováno v:
Biochemical pharmacology. 203
Human 5-lipoxygenase (5-LO) is the key enzyme of leukotriene biosynthesis, mostly expressed in leukocytes and thus a crucial component of the innate immune system. In this study, we show that 5-LO, besides its canonical function as an arachidonic aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f3e0976a0be89ac1b7582fc9605c2abd
https://pubmed.ncbi.nlm.nih.gov/35878796
https://pubmed.ncbi.nlm.nih.gov/35878796
Autor:
Sabine Seuter, Jyrki K. Virtanen, Marjo Malinen, Antonio Neme, Carsten Carlberg, Tarja Nurmi, Tomi-Pekka Tuomainen
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 188:71-76
In the vitamin D intervention study VitDbol (NCT02063334) blood samples were drawn directly before an oral bolus (2000 μg vitamin D3) and 24 h later. The focus of phase II of VitDbol was the transcriptome-wide analysis of the effects of vitamin D ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a62f2a416b73d54d450ceac8b5af8e
https://doi.org/10.1016/j.jsbmb.2018.11.019
https://doi.org/10.1016/j.jsbmb.2018.11.019
Autor:
Muhammad Ali, Zobia Anwar, Patrik Asp, Douglas A Bell, Mel Campbell, Carsten Carlberg, Melanie A. Carless, Xingqi Chen, Yashmin Choudhury, Marina de Castro Coêlho, Emma Dalan, Raima Das, Ryan R. Davis, Antonio del Sol, Kevin Dzobo, Tyler K. Fenstermaker, Sankar Kumar Ghosh, W.M. Grady, Michael Hausmann, Georg Hildenbrand, Manuela Hofner, Bradley Horn, Guoku Hu, Masaki Ito, Yoshihiro Izumiya, Anagha Joshi, Sascha Jung, Renata Z Jurkowska, Tomasz P Jurkowski, Yusuke Kishi, Julie Krainer, Ashish Kumar, Sharbadeb Kundu, Shaheen Laskar, Jin-Ho Lee, Dunaeva Marina, Alexander Mazo, Kaitlin N. Montanera, Kazuhiko Nakabayashi, Jennifer L. Neary, Antonio Neme, Christa Nöhammer, Jessica Nordlund, Naila Francis Paulo de Oliveira, Stephan Pabinger, Amit Paul, Svetlana Petruk, Walter Pulverer, Ho Sung Rhee, Nicole C. Riddle, Julia Romanowska, John M. Schoelz, Sabine Seuter, Sherin M. Shibin, Haruhiko Siomi, Miljana Tanić, Clifford G. Tepper, Changhai Tian, Trygve O. Tollefsbol, Jingjing Tong, Haruto Uchino, José Maria Chagas Viana Filho, Ma Wan, Zhihua Wang, Andreas Weinhäusel, A. Willbanks, Graham Williams, Yinping Xie, Soichiro Yamanaka, M. Yu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e36902e488f81c4c1b0e8a05df938423
https://doi.org/10.1016/b978-0-12-819414-0.09993-6
https://doi.org/10.1016/b978-0-12-819414-0.09993-6
Chromatin accessibility illustrates the density of nucleosome packaging and is a key feature of epigenetic analysis. Genomic DNA at accessible chromatin regions can be bound by transcription factors, polymerases and other nuclear proteins and often r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e9bbe04d918241c6ea3248d6b2d784d
https://doi.org/10.1016/b978-0-12-819414-0.00017-3
https://doi.org/10.1016/b978-0-12-819414-0.00017-3
Autor:
Tomi-Pekka Tuomainen, Sabine Seuter, Tarja Nurmi, Jyrki K. Virtanen, Carsten Carlberg, Antonio Neme
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 180:142-148
In vitro cell culture studies showed that the hormonal form of vitamin D3, 1α,25-dihydroxyvitamin D3, significantly (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf76ac23680095b0aef02dd21c7b46a0
https://doi.org/10.1016/j.jsbmb.2018.01.002
https://doi.org/10.1016/j.jsbmb.2018.01.002