Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sabine Scarzello"'
Autor:
Françoise Bernerd, Thierry Magnaldo, Marie-Françoise Avril, Sabine Scarzello, Yannick Gache, Emilie Warrick, Sophie Rouanet
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 10, Pp 20019-20036 (2013)
Somatic stem cells ensure tissue renewal along life and healing of injuries. Their safe isolation, genetic manipulation ex vivo and reinfusion in patients suffering from life threatening immune deficiencies (for example, severe combined immunodeficie
Externí odkaz:
https://doaj.org/article/b9ffad1771914a378114ce4812db1cb5
Autor:
Yannick Gache, Florence Brellier, Sophie Rouanet, Sahar Al-Qaraghuli, Maria Goncalves-Maia, Elodie Burty-Valin, Stéphanie Barnay, Sabine Scarzello, Martial Ruat, Nicolas Sevenet, Marie-Françoise Avril, Thierry Magnaldo
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145369 (2015)
Basal cell carcinoma (BCC) is the commonest tumor in human. About 70% sporadic BCCs bear somatic mutations in the PATCHED1 tumor suppressor gene which encodes the receptor for the Sonic Hedgehog morphogen (SHH). PATCHED1 germinal mutations are associ
Externí odkaz:
https://doaj.org/article/2c101475a48143828b551b89d6fc30d4
Publikováno v:
Expert Review of Dermatology. 8:249-256
Perspectives of genetic treatment adapted to orphan monogenic genodermatosis have been fueled by tremendous progress in molecular genetics and gene transfer technologies. Xeroderma pigmentosum is a prototype of cancer prone syndromes; it is caused by
Autor:
Gilles Pagès, Frédéric Checler, Peter Heutink, Jie Shen, Sabine Scarzello, Matthew S. Goldberg, Charlotte Druon, Guillaume Robert, Patrick Auberger, Sébastien Grosso, Emilie Giaime, Jacques Pouysségur, C. Alves da Costa, Claire Sunyach
Publikováno v:
Cell Death and Differentiation
Cell Death and Differentiation, Nature Publishing Group, 2009, epub ahead of print. ⟨10.1038/cdd.2009.116⟩
Cell Death and Differentiation, 17(1), 158-169. Nature Publishing Group
Giaime, E, Sunyach, C, Druon, C, Scarzello, S, Robert, G, Grosso, S, Auberger, P, Goldberg, M S, Shen, J, Heutink, P, Pouyssegur, J, Pages, G, Checler, F & da Costa, C A 2010, ' Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6 ', Cell Death and Differentiation, vol. 17, no. 1, pp. 158-169 . https://doi.org/10.1038/cdd.2009.116
Cell Death and Differentiation, Nature Publishing Group, 2009, epub ahead of print. ⟨10.1038/cdd.2009.116⟩
Cell Death and Differentiation, 17(1), 158-169. Nature Publishing Group
Giaime, E, Sunyach, C, Druon, C, Scarzello, S, Robert, G, Grosso, S, Auberger, P, Goldberg, M S, Shen, J, Heutink, P, Pouyssegur, J, Pages, G, Checler, F & da Costa, C A 2010, ' Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6 ', Cell Death and Differentiation, vol. 17, no. 1, pp. 158-169 . https://doi.org/10.1038/cdd.2009.116
International audience; DJ-1 was recently identified as a gene product responsible for a subset of familial Parkinson's disease (PD). The mechanisms by which mutations in DJ-1 alter its function and account for PD-related pathology remained largely u
Autor:
Thierry Magnaldo, Sophie Rouanet, Yannick Gache, Françoise Bernerd, Sabine Scarzello, Emilie Warrick, Marie-Françoise Avril
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2013, 14 (10), pp.20019-20036. ⟨10.3390/ijms141020019⟩
International Journal of Molecular Sciences, 2013, 14 (10), pp.20019-20036. ⟨10.3390/ijms141020019⟩
International Journal of Molecular Sciences, Vol 14, Iss 10, Pp 20019-20036 (2013)
International Journal of Molecular Sciences, MDPI, 2013, 14 (10), pp.20019-20036. ⟨10.3390/ijms141020019⟩
International Journal of Molecular Sciences, 2013, 14 (10), pp.20019-20036. ⟨10.3390/ijms141020019⟩
International Journal of Molecular Sciences, Vol 14, Iss 10, Pp 20019-20036 (2013)
International audience; Somatic stem cells ensure tissue renewal along life and healing of injuries. Their safe isolation, genetic manipulation ex vivo and reinfusion in patients suffering from life threatening immune deficiencies (for example, sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d48bade46597009a471ff991d53348
https://hal.sorbonne-universite.fr/hal-01583886/file/ijms-14-20019.pdf
https://hal.sorbonne-universite.fr/hal-01583886/file/ijms-14-20019.pdf
Autor:
Thierry Magnaldo, Florence Brellier, Nicolas Sevenet, Martial Ruat, Elodie Burty-Valin, Sahar Al-Qaraghuli, Yannick Gache, Maria Goncalves-Maia, Sabine Scarzello, Sophie Rouanet, Stéphanie Barnay, Marie-Françoise Avril
Publikováno v:
PLoS ONE
PLoS ONE, 2015, 10 (12), pp.e0145369. ⟨10.1371/journal.pone.0145369⟩
PLoS ONE, Public Library of Science, 2015, 10 (12), pp.e0145369. ⟨10.1371/journal.pone.0145369⟩
PLoS ONE, Vol 10, Iss 12, p e0145369 (2015)
PLoS ONE, 2015, 10 (12), pp.e0145369. ⟨10.1371/journal.pone.0145369⟩
PLoS ONE, Public Library of Science, 2015, 10 (12), pp.e0145369. ⟨10.1371/journal.pone.0145369⟩
PLoS ONE, Vol 10, Iss 12, p e0145369 (2015)
International audience; Basal cell carcinoma (BCC) is the commonest tumor in human. About 70% sporadic BCCs bear somatic mutations in the PATCHED1 tumor suppressor gene which encodes the receptor for the Sonic Hedgehog morphogen (SHH). PATCHED1 germi
Autor:
Christine Payré, Khaoula Chargui, Rob C. Oslund, Sabine Scarzello, Michael H. Gelb, Hiromi, Gérard Lambeau, Anne Sophie Dabert-Gay, Dominique Douguet, Ikram Jemel
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2011, 286 (42), pp.36509-21. ⟨10.1074/jbc.M111.268540⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2011, 286 (42), pp.36509-21. ⟨10.1074/jbc.M111.268540⟩
International audience; Among mammalian secreted phospholipases A(2) (sPLA(2)s), group X sPLA(2) has the most potent hydrolyzing activity toward phosphatidylcholine and is involved in arachidonic acid (AA) release. Group X sPLA(2) is produced as a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d57b628710360d03826cb50fffaa8a6
https://hal.archives-ouvertes.fr/hal-00731333
https://hal.archives-ouvertes.fr/hal-00731333
Autor:
Sabine Scarzello, Charlotte Druon, Claire Sunyach, Frédéric Checler, Marie-Victoire Guillot-Sestier
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, 284 (51), pp.35973-86. ⟨10.1074/jbc.M109.051086⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, 284 (51), pp.35973-86. ⟨10.1074/jbc.M109.051086⟩
International audience; Cellular prion protein (PrP(c)) undergoes a disintegrin-mediated physiological cleavage, generating a soluble amino-terminal fragment (N1), the function of which remained unknown. Recombinant N1 inhibits staurosporine-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d094d9b28dec1225a1c8cbc32d97b7ed
https://hal.archives-ouvertes.fr/hal-00497181
https://hal.archives-ouvertes.fr/hal-00497181
Autor:
Gérard Lambeau, Morgane Rouault, Sabine Scarzello, Michael H. Gelb, Fanny Surrel, Eric Boilard, Sofiane Bezzine, Catherine Le Calvez, Farideh Ghomashchi, James G. Bollinger, Alan G. Singer
Publikováno v:
Biochemistry
Biochemistry, American Chemical Society, 2007, 46 (6), pp.1647-62. ⟨10.1021/bi062119b⟩
Biochemistry, American Chemical Society, 2007, 46 (6), pp.1647-62. ⟨10.1021/bi062119b⟩
To date, 12 secreted phospholipases A2 (sPLA2s) have been identified in the mouse species and divided into three structural collections (I/II/V/X, III, and XII). On the basis of their different molecular properties and tissue distributions, each sPLA
A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons
Autor:
Sylvie Diochot, Michel Lazdunski, Pierre Escoubas, Anne Baron, Lachlan D. Rash, Miguel Salinas, Emmanuel Deval, Sabine Scarzello
Publikováno v:
EMBO Journal
EMBO Journal, EMBO Press, 2004, 23 (7), pp.1516-1525. ⟨10.1038/sj.emboj.7600177⟩
EMBO Journal, EMBO Press, 2004, 23, pp.1516-1525
EMBO Journal, 2004, 23 (7), pp.1516-1525. ⟨10.1038/sj.emboj.7600177⟩
EMBO Journal, EMBO Press, 2004, 23 (7), pp.1516-1525. ⟨10.1038/sj.emboj.7600177⟩
EMBO Journal, EMBO Press, 2004, 23, pp.1516-1525
EMBO Journal, 2004, 23 (7), pp.1516-1525. ⟨10.1038/sj.emboj.7600177⟩
From a systematic screening of animal venoms, we isolated a new toxin (APETx2) from the sea anemone Anthopleura elegantissima, which inhibits ASIC3 homomeric channels and ASIC3-containing heteromeric channels both in heterologous expression systems a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3487e0332fcd26c84ce77c8b33ff5a
https://hal.archives-ouvertes.fr/hal-02277235
https://hal.archives-ouvertes.fr/hal-02277235