Výsledky vyhledávání - "Sabine Rothmann"

Plasma homoarginine, arginine, asymmetric dimethylarginine and total homocysteine interrelationships in rheumatoid arthritis, coronary artery disease and peripheral artery occlusion disease

Autor: Jessica Y. Schneider, Andreas Hahn, Dimitrios Tsikas, Arslan Arinc Kayacelebi, Janina Willers, Jürgen C. Frölich, Vu Vi Pham, Sabine Rothmann

Publikováno v: Amino Acids. 47:1885-1891

Elevated circulating concentrations of total l-homocysteine (thCys) and free asymmetric dimethylarginine (ADMA) are long-established cardiovascular risk factors. Low circulating l-homoarginine (hArg) concentrations were recently found to be associate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bec3cf4f6ab3aea711b0291fea697cd
https://doi.org/10.1007/s00726-015-1915-3

Zobrazit plný text záznamu

Simultaneous GC-MS/MS measurement of malondialdehyde and 4-hydroxy-2-nonenal in human plasma: Effects of long-term L-arginine administration

Autor: Frank-Mathias Gutzki, Jessica Y. Schneider, Sabine Rothmann, Dimitrios Tsikas, Jürgen C. Frölich, Bibiana Beckmann

Publikováno v: Analytical biochemistry. 524

Here, we report the simultaneous derivatization and quantification of malondialdehyde (MDA) and 4-hydroxy-2-nonenal (HNE) in human plasma by GC-MS/MS using [1,3-2H2]-MDA (d2-MDA) and [9,9,9-2H3]-HNE (d3-HNE) as the internal standards, respectively. M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb4d145a84a1baaad97e18309df5b20
https://pubmed.ncbi.nlm.nih.gov/27530652

Zobrazit plný text záznamu

Development, validation and biomedical applications of stable-isotope dilution GC-MS and GC-MS/MS techniques for circulating malondialdehyde (MDA) after pentafluorobenzyl bromide derivatization: MDA as a biomarker of oxidative stress and its relation to 15(S)-8-iso-prostaglandin F2α and nitric oxide (NO)

Autor: Arne Trettin, Jürgen C. Frölich, Darko Modun, Sabine Rothmann, Dimitrios Tsikas, Norbert Maassen, Maria-Theresia Suchy, Nadine Stuke, Jessica Y. Schneider

Publikováno v: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1019

Malondialdehyde (MDA, CH2(CHO)2) is one of the best investigated and most frequently measured biomarkers of lipid peroxidation in biological fluids, a constituent of the so called thiobarbituric acid reactive substances (TBARS). The reaction of thiob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b461efe46f9bf15942e425d72557ff44
https://pubmed.ncbi.nlm.nih.gov/26522895

Zobrazit plný text záznamu

Effects of chronic oral L-arginine administration on the L-arginine/NO pathway in patients with peripheral arterial occlusive disease or coronary artery disease: L-Arginine prevents renal loss of nitrite, the major NO reservoir

Autor: Dimitrios Tsikas, Jennifer Langen, Sabine Rothmann, Jean François Huneau, Jürgen C. Frölich, Jessica Y. Schneider, François Mariotti, Frank Schröder, Thomas Lücke

Publikováno v: Amino Acids
Amino Acids, Springer Verlag, 2015, 47 (9), pp.1961-1974. ⟨10.1007/s00726-015-2031-0⟩

Despite saturation of nitric oxide (NO) synthase (NOS) by its substrate l-arginine (Arg), oral and intravenous supplementation of Arg may enhance NO synthesis, a phenomenon known as "The l-arginine paradox". Yet, Arg is not only a source of NO, but i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659ea2c29fedf87c218df18a13cb77ec
https://hal.archives-ouvertes.fr/hal-01535302

Zobrazit plný text záznamu

Biosynthesis of homoarginine (hArg) and asymmetric dimethylarginine (ADMA) from acutely and chronically administered free L-arginine in humans

Autor: Dimitrios Tsikas, Sabine Rothmann, Kristine Chobanyan-Jürgens, Thomas Lücke, Jean François Huneau, K Weigt-Usinger, Jessica Y. Schneider, François Mariotti, Edzard Schwedhelm, Dorothee Atzler, Jürgen C. Frölich, Chi-Un Choe, Arslan Arinc Kayacelebi, Jennifer Langen

Publikováno v: Amino Acids
Amino Acids, Springer Verlag, 2015, 47 (9), pp.1893-1908. ⟨10.1007/s00726-015-2012-3⟩

Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide (NO) synthesis, whereas l-arginine (Arg) and l-homoarginine (hArg) serve as substrates for NO synthesis. ADMA and other methylated arginines are generally believed to exclu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52a692b42ef93760f535ee30cc4cb95
https://hal.archives-ouvertes.fr/hal-01535301

Zobrazit plný text záznamu

Glutathione promotes prostaglandin H synthase (cyclooxygenase)-dependent formation of malondialdehyde and 15(S)-8-iso-prostaglandin F2α

Autor: Frank-Mathias Gutzki, Sabine Rothmann, Dirk O. Stichtenoth, Paschalis Tossios, Yessica Schneider, Jürgen C. Frölich, Maria-Theresia Suchy, Dimitrios Tsikas, Jonas Niemann

Publikováno v: FEBS letters. 586(20)

Prostaglandin (PG) H synthases (PGHS) or cyclooxygenases (COX) catalyse the peroxidation of arachidonic acid (AA) to PGG(2) and PGH(2) which are further converted to a series of prostaglandins and thromboxane A(2). Here, we report that GSH promotes c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0819a769a32127d5b2e35a5d40d133d1
https://pubmed.ncbi.nlm.nih.gov/22982857

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání