Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Sabine Pestel"'
Autor:
Steffi Knoll Machado, Hendrik Peil, Timo Kraushaar, Philipp Claar, Marcel Mischnik, Holger Lind, Eva Herzog, Michael Bacher, Marc Wolfgang Nolte, Maximilian Bielohuby, Sabine Pestel, Padmapriya Ponnuswamy
Publikováno v:
Thrombosis and Haemostasis.
Background: There is an emerging concept that in addition to circulating coagulation factor IX (FIX), extravascular FIX contributes to hemostasis. Objective: Evaluate efficacy of extravascular FIX using animal models of tail clip bleeding and ferric
Autor:
Anton Zalewski, Arna Andrews, Isabelle Glauser, Marcel Mischnik, Matthew P. Hardy, Anne M Verhagen, Kerstin Emmrich, Sabine Pestel, Con Panousis, Philipp Claar, Victor Turnbull, Chao-Guang Chen, Michael J. Wilson, Gregory T. Bass, Elmar Raquet, Steve K. Dower, Jenny Chia, Thomas Weimer, Vesna Tomasetig
Publikováno v:
Journal of Thrombosis and Haemostasis. 19:2710-2725
BACKGROUND We have recently reported on a recombinant von Willebrand factor (VWF) D'D3 albumin fusion protein (rD'D3-FP) developed to extend the half-life of coagulation factor VIII (FVIII) for the treatment of hemophilia A. Based on predictive model
Autor:
Steffi Knoll Machado, Hendrik Peil, Timo Kraushaar, Philipp Claar, Marcel Mischnik, Eva Herzog, Michael Bacher, Marc Wolfgang Nolte, Maximilian Bielohuby, Sabine Pestel, Padmapriya Ponnuswamy
Publikováno v:
Blood. 140:2701-2702
Autor:
J Röder, MW Nolte, T Kraushaar, M Bacher, Sabine Pestel, P Ponnuswamy, Philipp Claar, C Hardy, S Knoll Machado
Publikováno v:
65th Annual Meeting of the Society of Thrombosis and Haemostasis Research.
Autor:
Sabine Pestel, C Hardy, Philipp Claar, J Riedesel, K Schön, Marcel Mischnik, W Azar, W Seyfert-Brandt, MW Nolte
Publikováno v:
65th Annual Meeting of the Society of Thrombosis and Haemostasis Research.
Autor:
Elmar Raquet, Hendrik Peil, Padmapriya Ponnuswamy, Eva Herzog, Sabine Pestel, Marcel Mischnik, Philipp Claar, Steffi Knoll Machado, Oliver Ghobrial
Publikováno v:
Blood. 138:3180-3180
Introduction: The recessive X-linked bleeding disorder Hemophilia B is caused by a mutation in the coagulation factor (F) IX gene leading to partial or total loss of its function. Preventive treatment with replacement long-acting FIX is an attractive
Autor:
Alireza Rezvani-Sharif, Piet H. van der Graaf, Sabine Pestel, Oliver Ghobrial, Steve K. Dower, Eva Herzog, Anne M Verhagen, Ineke L. Muir, Markus Brechmann, Douglas Chung, Sivarmurthy Krupa
Publikováno v:
Blood. 138:4240-4240
Background and Aims: Replacement FIX therapy (rIX) is an effective treatment for hemophilia B even with undetectable levels in the blood 1. However, the mechanistic reason for hemostasis with low plasma levels is not well understood. There is growing
Autor:
Jason Simmonds, Anna Tjärnlund-Wolf, Holger Lind, Arna Andrews, Philipp Claar, Stefan Schulte, Sabine Pestel, Steven K. Dower, Peter Schmidt, Marcel Mischnik, Thomas Weimer, Vesna Tomasetig, Elmar Raquet, Hans-Wilhelm Beltz
Publikováno v:
Blood Adv
A novel mechanism for extending the circulatory half-life of coagulation factor VIII (FVIII) has been established and evaluated preclinically. The FVIII binding domain of von Willebrand factor (D′D3) fused to human albumin (rD′D3-FP) dose depende
Autor:
Eva Herzog, Michael J. Wilson, Elmar Raquet, Marcel Mischnik, Arna Andrews, Sabine Pestel, Steve K. Dower, Philipp Claar, Thomas Weimer
Publikováno v:
Science meets clinical practice.
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 105:106901
Introduction The implementation of novel, reliable biomarkers for the early and differential diagnosis of acute kidney injury (AKI) could greatly improve the timely treatment and prevention of disease progression, particularly since the current gold