Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sabine Novak"'
Autor:
Martin Filipits, Thomas Gruenberger, Christine Pirker, Anita Brandstetter, Sabine Novak, Katharina Schmid, Harald Puhalla, Walter Berger, Beata Herberger
The prognosis of patients with biliary tract adenocarcinomas (BTA) is still poor due to lack of effective systemic treatment options. Knowledge of the molecular mechanisms involved in the pathogenesis of this disease is of importance for the developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0061a9f8fc146b05304901be91aa9740
https://doi.org/10.1158/1535-7163.c.6531569.v1
https://doi.org/10.1158/1535-7163.c.6531569.v1
Autor:
Martin Filipits, Thomas Gruenberger, Christine Pirker, Anita Brandstetter, Sabine Novak, Katharina Schmid, Harald Puhalla, Walter Berger, Beata Herberger
Supplementary Tables from Simultaneous blockade of the epidermal growth factor receptor/mammalian target of rapamycin pathway by epidermal growth factor receptor inhibitors and rapamycin results in reduced cell growth and survival in biliary tract ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b10afbdf4a5c39875c941196ca81907
https://doi.org/10.1158/1535-7163.22484759.v1
https://doi.org/10.1158/1535-7163.22484759.v1
Autor:
Fritz Wrba, Beata Herberger, Martin Filipits, Anita Brandstetter, Martina Lehnert, Robert Pirker, Thomas Gruenberger, Birgit Gruenberger, Harald Puhalla, Sabine Novak
Publikováno v:
Clinical Cancer Research. 13:4795-4799
Purpose: The mammalian target of rapamycin (mTOR) is a protein kinase that plays a key role in cellular growth and homeostasis. Because its regulation is frequently altered in tumors, mTOR is currently under investigation as a potential target for an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c858f5beef2e2fb6af6997119b4c64dc
https://doi.org/10.1158/1078-0432.ccr-07-0738
https://doi.org/10.1158/1078-0432.ccr-07-0738
Autor:
Wolfgang J. Schneider, Johannes Nimpf, Sabine Novak, Jan Bauer, Walter Stockinger, Elke Hengstschläger-Ottnad, Andrew Matus, Manfred Hüttinger, Hans Lassmann
Publikováno v:
Journal of Biological Chemistry. 273:32213-32221
LR7/8B is a member of the low density lipoprotein receptor gene family that is specifically synthesized in the brain. Here we have functionally expressed in 293 cells the splice variant harboring eight ligand binding repeats (LR8B). As assessed by co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4be71f7082277cab40424084add0b4f2
https://doi.org/10.1074/jbc.273.48.32213
https://doi.org/10.1074/jbc.273.48.32213
Autor:
Brian R. Krause, Aldons J. Lusis, Sandra K. Erickson, Steven R. Lear, Sabine Novak, Carrie B. Welch, Thomas A. Spencer, Yaowu Zheng, Heather M. Myers, Eric Sande, Robert V. Farese, Sylvaine Cases
Publikováno v:
Journal of Biological Chemistry. 273:26755-26764
The synthesis of cholesterol esters by acyl-CoA:cholesterol acyltransferase (ACAT, EC 2.3.1.26) is an important component of cellular cholesterol homeostasis. Cholesterol ester formation also is hypothesized to be important in several physiologic pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b93b4e19a5a56f55dd38f5efcf6c1ac
https://doi.org/10.1074/jbc.273.41.26755
https://doi.org/10.1074/jbc.273.41.26755
Autor:
Vardiella L. Meiner, Sabine Novak, Li-Ming Dong, Sandra K. Erickson, Karl H. Weisgraber, Robert V. Farese, Heather M. Myers, Michael D. Gunn, Carmen Tam
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 9, Pp 1928-1933 (1997)
Cholesterol esterification is involved in the regulation of cellular cholesterol content and has been hypothesized to play a role in important physiologic processes including intestinal cholesterol absorption, hepatic lipoprotein production, and macr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf23d5381eb48106484485486393c84
http://www.sciencedirect.com/science/article/pii/S0022227520371686
http://www.sciencedirect.com/science/article/pii/S0022227520371686
Autor:
Joachim Herz, Johannes Nimpf, Wolfgang J. Schneider, Christian Brandes, Walter Stockinger, Sabine Novak
Publikováno v:
Genomics. 42:185-191
Apolipoprotein E-mediated lipid metabolism in the central nervous system plays an important role in cholesterol and phospholipid homeostasis of this organ, which is separated from the circulation by the blood–brain barrier. Moreover, in late-onset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb2349845151559a353871398cc76aed
https://doi.org/10.1006/geno.1997.4702
https://doi.org/10.1006/geno.1997.4702
Autor:
Gerwin, Heller, Barbara, Ziegler, Anita, Brandstetter, Sabine, Novak, Margaretha, Rudas, Guido, Hennig, Mathias, Gehrmann, Torsten, Acht, Sabine, Zöchbauer-Müller, Martin, Filipits
Publikováno v:
Anticancer research. 29(10)
Loss of cyclin-dependent kinase (CDK) 10 expression may be an important mechanism of tamoxifen resistance and the 5' CpG island associated with the CDK10 gene has been suggested to be a target for aberrant methylation in breast cancer.The methylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2540eefca449dc045efc9ba3b6f3f23b
https://pubmed.ncbi.nlm.nih.gov/19846932
https://pubmed.ncbi.nlm.nih.gov/19846932
Autor:
Christine Pirker, Walter Berger, Thomas Gruenberger, Anita Brandstetter, Martin Filipits, Harald Puhalla, Beata Herberger, Sabine Novak, Katharina Schmid
Publikováno v:
Molecular cancer therapeutics. 8(6)
The prognosis of patients with biliary tract adenocarcinomas (BTA) is still poor due to lack of effective systemic treatment options. Knowledge of the molecular mechanisms involved in the pathogenesis of this disease is of importance for the developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d34eea9789a2969b53c143019d2d82
https://pubmed.ncbi.nlm.nih.gov/19509244
https://pubmed.ncbi.nlm.nih.gov/19509244
Autor:
Kami Kim, Sabrina Sonda, Jacquelyn J. Maher, Joel D. Ernst, Sabine Novak, Robert V. Farese, Li Min Ting
Publikováno v:
The Journal of biological chemistry. 276(37)
Upon host cell invasion the apicomplexan parasite Toxoplasma gondii resides in a specialized compartment termed the parasitophorous vacuole that is derived from the host cell membrane but modified by the parasite. Despite the segregation of the paras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a281e44a3c7c573244419ead08b845
https://pubmed.ncbi.nlm.nih.gov/11457847
https://pubmed.ncbi.nlm.nih.gov/11457847