Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Sabine Muth"'
Autor:
Julian Sohl, Ann-Kathrin Hartmann, Jennifer Hahlbrock, Joschka Bartneck, Michael Stassen, Matthias Klein, Matthias Bros, Stephan Grabbe, Federico Marini, Kevin Woods, Borhane Guezguez, Matthias Mack, Hansjörg Schild, Sabine Muth, Felix Melchior, Hans Christian Probst, Peter Langguth, Markus P. Radsak
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/f8b0c33b4f3c4a62a0d15ea12f4f381c
Autor:
Joschka Bartneck, Ann-Kathrin Hartmann, Lara Stein, Danielle Arnold-Schild, Matthias Klein, Michael Stassen, Federico Marini, Jonas Pielenhofer, Sophie Luise Meiser, Peter Langguth, Matthias Mack, Sabine Muth, Hans-Christian Probst, Hansjörg Schild, Markus Philipp Radsak
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Tumor development and progression is shaped by the tumor microenvironment (TME), a heterogeneous assembly of infiltrating and resident host cells, their secreted mediators and intercellular matrix. In this context, tumors are infiltrated by various i
Externí odkaz:
https://doaj.org/article/b6b81cbb0f6c4c90b928a7619a5c1a38
Autor:
Ann-Kathrin Hartmann, Joschka Bartneck, Jonas Pielenhofer, Sophie Luise Meiser, Danielle Arnold-Schild, Matthias Klein, Michael Stassen, Hansjörg Schild, Sabine Muth, Hans Christian Probst, Peter Langguth, Stephan Grabbe, Markus P. Radsak
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTranscutaneous immunization (TCI) is a non-invasive vaccination method promoting strong cellular immune responses, crucial for the immunological rejection of cancer. Previously, we reported on the combined application of the TLR7 agonist
Externí odkaz:
https://doaj.org/article/45104fbc88c34ace9bbdff9da15c6608
Autor:
Julian Sohl, Ann-Kathrin Hartmann, Jennifer Hahlbrock, Joschka Bartneck, Michael Stassen, Matthias Klein, Matthias Bros, Stephan Grabbe, Federico Marini, Kevin Woods, Borhane Guezguez, Matthias Mack, Hansjörg Schild, Sabine Muth, Felix Melchior, Hans Christian Probst, Peter Langguth, Markus P. Radsak
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract Transcutaneous immunization (TCI) utilizing the TLR7 agonist imiquimod (IMQ-TCI) induces T cell-driven protective immunity upon application onto intact skin. In our present work, we combine the anti-psoriatic agent dithranol with IMQ-TCI to
Externí odkaz:
https://doaj.org/article/7d6f5fd597ff43259826599506c19bbf
Autor:
Sabine Muth, Tobias Bopp, Cinthia Silva-Vilches, Markus P. Radsak, Julian Sohl, Felix Melchior, Georg Bündgen, Hela Weslati, Karsten Mahnke, Tobias Hain, Nadine Kamenjarin, Hans Christian Probst, Björn E. Clausen, Kristian Schütze, Hansjörg Schild, Sven Danckwardt
Publikováno v:
Journal of Investigative Dermatology. 139:422-429
Dendritic cells (DCs) are important inducers and regulators of T-cell responses. They are able to activate and modulate the differentiation of CD4+ and CD8+ T cells. In the skin, there are at least five phenotypically distinct DC subpopulations that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ca898c57228bd694acb6526ba3d8d6
https://doi.org/10.1016/j.jid.2018.08.022
https://doi.org/10.1016/j.jid.2018.08.022
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 100(3)
Abstract Regulatory T cells (Tregs) suppress immune responses and thus contribute to immune homeostasis. On the downside, Tregs also limit immune responses against tumors promoting the progression of cancer. Among the many mechanisms implied in Treg-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f81d85f4a2bc9cb99a27de49b81a208
https://pubmed.ncbi.nlm.nih.gov/34423375
https://pubmed.ncbi.nlm.nih.gov/34423375
Autor:
Matthias Klein, Martina Dorsch, Michael Kofoed-Branzk, Pia-Katharina Larsen, Stephanie C. Ganal-Vonarburg, Laura Schaupp, Sven Jäckel, Siegfried Weiss, Andreas Diefenbach, Andrew J. Macpherson, Vanessa Schmitt, Sabine Muth, Hans Christian Probst, Felix Melchior, Julia Spanier, Kristian Schütze, Thomas Schwanz, Leif Rogell, Stefan Lienenklaus, Fabian Guendel, Tobias Bopp, Hansjörg Schild, Tobias Hain, Mir-Farzin Mashreghi, Ulrike Grundmann, Ulrich Kalinke, Christoph Reinhardt, Pawel Durek, Karsten Mahnke, Sven Danckwardt, Tobias B. Huber, Christoph Wilhelm, Oliver Kretz, Gitta Anne Heinz
Publikováno v:
Cell
United States
United States
Summary Environmental signals shape host physiology and fitness. Microbiota-derived cues are required to program conventional dendritic cells (cDCs) during the steady state so that they can promptly respond and initiate adaptive immune responses when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492822246d126a29510f0e0a9bba9e23
https://doi.org/10.1016/j.cell.2020.04.022
https://doi.org/10.1016/j.cell.2020.04.022
Autor:
Dennis Vogel, Sabine Muth, Jochem Koenig, Danielle Arnold-Schild, Vanessa Popp, Jacques Pouysségur, Natascha Luther, Jennifer Hahlbrock, Steffen Rapp, Hans Christian Probst, Magdalena Huber, Pamela Aranda Lopez, Marina Kreutz, Kathrin Renner, Esther von Stebut, Toszka Bohn, Christina Lueckel, Shogo Endo, Stefanie Pektor, Tobias Bopp, Till-Julius Bruehl, Matthias Klein, Christian Becker, Hansjoerg Schild, Katharina Gerlach, Nobuhiko Kojima, Almut Brand, Benno Weigmann, Edgar Schmitt
Publikováno v:
Nature immunology. 19(12)
Many tumors evolve sophisticated strategies to evade the immune system, and these represent major obstacles for efficient antitumor immune responses. Here we explored a molecular mechanism of metabolic communication deployed by highly glycolytic tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affd2ef4a5a486663d99902a33571cdd
https://pubmed.ncbi.nlm.nih.gov/30397351
https://pubmed.ncbi.nlm.nih.gov/30397351
Autor:
Susanne Hahn, Toszka Bohn, Hansjörg Schild, Alexander Ulges, Frauke Zipp, Nadine Grebe, Tobias Bopp, Ari Waisman, Sonja Reißig, Andreas Beilhack, Sabine Muth, Natascha Stergiou, Sebastian Reuter, Till-Julius Brühl, Matthias Klein, Markus Hoffmann, Odile Filhol-Cochet, Irma Haben, Edgar Schmitt, Hajime Yurugi, Hans Christian Probst, Krishnaraj Rajalingam, Brigitte Boldyreff, Thierry Buchou, Iris Bellinghausen, Minka Breloer, Bastian Gerlitzki, Helmut Jonuleit, Andrea Tuettenberg, Valérie Staudt
Publikováno v:
Nature Immunology. 16:267-275
The quality of the adaptive immune response depends on the differentiation of distinct CD4(+) helper T cell subsets, and the magnitude of an immune response is controlled by CD4(+)Foxp3(+) regulatory T cells (Treg cells). However, how a tissue- and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745a754685d64a3fc15d630c1f5a41cc
https://doi.org/10.1038/ni.3083
https://doi.org/10.1038/ni.3083
Publikováno v:
European Journal of Immunology. 44:927-933
Dendritic cells (DCs) are master regulators of T-cell responses. After sensing pathogen-derived molecular patterns (PAMPs), or signals of inflammation and cellular stress, DCs differentiate into potent activators of naive CD4(+) and CD8(+) T cells th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38ac83f1c4b0cdc60fd9a26441d41e8e
https://doi.org/10.1002/eji.201343862
https://doi.org/10.1002/eji.201343862