Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sabine Macho‐Maschler"'
Autor:
Sabina Ostermeier, Rupert Palme, Ingrid Vervuert, Barbara Glomm, Karsten Feige, Sabine Macho-Maschler, Uta König von Borstel, Monica Venner
Publikováno v:
Animals, Vol 14, Iss 22, p 3332 (2024)
In this study, gastroscopy was performed twice in 31 two-year-old Thoroughbred racehorses in training. Salivary cortisol (SC) and fecal cortisol metabolite (FCM) concentrations were determined to measure the stress impact. One gastroscopy was perform
Externí odkaz:
https://doaj.org/article/e4608913ebf04967a757b0e31381e6ce
Autor:
Anita Manz, Karin Allenspach, Stefan Kummer, Barbara Richter, Ingrid Walter, Sabine Macho‐Maschler, Alexander Tichy, Iwan A Burgener, Nicole Luckschander‐Zeller
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 35, Iss 3, Pp 1288-1296 (2021)
Abstract Background In inflammatory bowel disease (IBD) in humans, phosphorylated signal transducer and activator of transcription 3 (pSTAT3) is upregulated in mucosal epithelial cells and correlates with clinical severity. Hypothesis/Objective To in
Externí odkaz:
https://doaj.org/article/35af696ad3974bba94f9d156acbd48d6
Autor:
Katharina Woess, Sabine Macho-Maschler, Dorette S. van Ingen Schenau, Miriam Butler, Caroline Lassnig, Daniel Valcanover, Andrea Poelzl, Katrin Meissl, Barbara Maurer, Tania Brandstoetter, Claus Vogl, Anna Koren, Stefan Kubicek, Anna Orlova, Richard Moriggl, Birgit Strobl, Veronika Sexl, Frank N. van Leeuwen, Roland P. Kuiper, Mathias Mueller
Publikováno v:
Haematologica, Vol 108, Iss 4 (2022)
Tyrosine kinase 2 (TYK2) is a member of the Janus kinase/signal transducer and activator of transcription pathway, which is central in cytokine signaling. Previously, germline TYK2 mutations have been described in two patients developing de novo T-ce
Externí odkaz:
https://doaj.org/article/16495fc0f1644407926d2399569c73ec
Autor:
Markus K Muellner, Barbara Mair, Yasir Ibrahim, Claudia Kerzendorfer, Hannelore Lechtermann, Claudia Trefzer, Freya Klepsch, André C Müller, Ernestine Leitner, Sabine Macho‐Maschler, Giulio Superti‐Furga, Keiryn L Bennett, José Baselga, Uwe Rix, Stefan Kubicek, Jacques Colinge, Violeta Serra, Sebastian MB Nijman
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 2, Pp 1-16 (2015)
Abstract Some mutations in cancer cells can be exploited for therapeutic intervention. However, for many cancer subtypes, including triple‐negative breast cancer (TNBC), no frequently recurring aberrations could be identified to make such an approa
Externí odkaz:
https://doaj.org/article/034f9bbfb32d4b97b689c5cf0c981ff6
Autor:
Valerio Donini, Elisa Iacona, Luca Pedrotti, Sabine Macho-Maschler, Rupert Palme, Luca Corlatti
Publikováno v:
The Science of Nature. 109
Fecal cortisol metabolites (FCMs) are widely used to track stress responses in wildlife and captive species. Rules of thumb suggest that samples should be collected as soon as possible after defecation, to avoid decay of FCMs. To date, however, only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002021cefebf7192561289856fa2f2c2
https://doi.org/10.1007/s00114-022-01792-y
https://doi.org/10.1007/s00114-022-01792-y
Autor:
Katharina, Woess, Sabine, Macho-Maschler, Dorette S, Van Ingen Schenau, Miriam, Butler, Caroline, Lassnig, Daniel, Valcanover, Andrea, Poelzl, Katrin, Meissl, Barbara, Maurer, Tania, Brandstoetter, Claus, Vogl, Anna, Koren, Stefan, Kubicek, Anna, Orlova, Richard, Moriggl, Birgit, Strobl, Veronika, Sexl, Frank N, Van Leeuwen, Roland P, Kuiper, Mathias, Mueller
Publikováno v:
Haematologica.
Tyrosine kinase 2 (TYK2) is a member of the Janus kinase/signal transducer and activator of transcription pathway, which is central in cytokine signaling. Previously, germline TYK2 mutations have been described in two patients developing de novo T-ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::059b95fc218442272410eaf838ee374b
https://pubmed.ncbi.nlm.nih.gov/35021603
https://pubmed.ncbi.nlm.nih.gov/35021603
Autor:
Barbara Richter, Karin Allenspach, Anita Manz, Nicole Luckschander-Zeller, Alexander Tichy, Ingrid Walter, Sabine Macho-Maschler, Iwan Burgener, Stefan Kummer
Publikováno v:
Journal of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine, Vol 35, Iss 3, Pp 1288-1296 (2021)
Journal of Veterinary Internal Medicine, Vol 35, Iss 3, Pp 1288-1296 (2021)
Background In inflammatory bowel disease (IBD) in humans, phosphorylated signal transducer and activator of transcription 3 (pSTAT3) is upregulated in mucosal epithelial cells and correlates with clinical severity. Hypothesis/Objective To investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5dfe6314e3347599e9bd3a00ebe81bb
https://pubmed.ncbi.nlm.nih.gov/33955083
https://pubmed.ncbi.nlm.nih.gov/33955083
Autor:
Anzhelika, Karjalainen, Stephen, Shoebridge, Milica, Krunic, Natalija, Simonović, Graham, Tebb, Sabine, Macho-Maschler, Birgit, Strobl, Mathias, Müller
Publikováno v:
Cancers, Vol 12, Iss 1, p 150 (2020)
Cancers
Cancers
We review the history of the tyrosine kinase 2 (TYK2) as the founding member of the Janus kinase (JAK) family and outline its structure-function relation. Gene-targeted mice and hereditary defects of TYK2 in men have established the biological and pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d27e493735375bf9048db4d5b6e91783
https://www.mdpi.com/2072-6694/12/1/150
https://www.mdpi.com/2072-6694/12/1/150
Autor:
Katharina, Wöss, Natalija, Simonović, Birgit, Strobl, Sabine, Macho-Maschler, Mathias, Müller
Publikováno v:
Cancers, Vol 11, Iss 11, p 1728 (2019)
Cancers
Cancers
In this review we concentrate on the recent findings describing the oncogenic potential of the protein tyrosine kinase 2 (TYK2). The overview on the current understanding of TYK2 functions in cytokine responses and carcinogenesis focusses on the acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0af26e49766b704332dc50c9900195b4
https://www.mdpi.com/2072-6694/11/11/1728
https://www.mdpi.com/2072-6694/11/11/1728
Autor:
Sabine Macho-Maschler, Rita Rom, Mathias Müller, Juliana Kornhoff, Andrea Poelzl, Riem Gawish, Ulrich Kalinke, Luca Ferrarese, Jasmin Svinka, Lena Amenitsch, Natalija Simonović, Zsuzsanna Bago-Horvath, Robert Eferl, Stipan Jonjić, Therese Lederer, Tanja Bulat, Dagmar Stoiber, Mario Biaggio, Michaela Prchal-Murphy, Veronika Sexl, Birgit Strobl, Astrid Krmpotić, Markus Bosmann, Caroline Lassnig
Publikováno v:
Cell Reports
Volume 26
Issue 9
Cell reports
Volume 26
Issue 9
Cell reports
Cytomegalovirus (CMV) has a high prevalence worldwide, is often fatal for immunocompromised patients, and causes bone marrow suppression. Deficiency of signal transducer and activator of transcription 1 (STAT1) results in severely impaired antiviral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0543abcf8782da6ca79b2dbe623d9967
https://doi.org/10.1016/j.celrep.2019.02.017
https://doi.org/10.1016/j.celrep.2019.02.017
