Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sabine M.W. van Rossenberg"'
Autor:
Theo J.C. Van Berkel, Karen Sliedregt-Bol, Sabine M.W. van Rossenberg, Perry Prince, Erik A.L. Biessen, Jacques H. van Boom, Gijs A. van der Marel
Publikováno v:
Bioconjugate Chemistry. 14:1077-1082
Peptide nucleic acids (PNA's) have shown to hold potential as antisense drugs. In this study we have designed PNA drugs for the microsomal triglyceride transfer protein (MTP), which is known to play a critical role in the assembly of atherogenic lipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c5b1d08f015ab30fda3048901b9123
https://doi.org/10.1021/bc0340417
https://doi.org/10.1021/bc0340417
Autor:
Jacques H. van Boom, Theo J.C. Van Berkel, Karen Sliedregt-Bol, Sabine M.W. van Rossenberg, Gerben Koning, Gijs A. van der Marel, Hans van den Elst, Erik A.L. Biessen
Publikováno v:
ChemBioChem. 4:633-639
Colchicine, an established tubulin inhibitor, interferes with the trafficking of endocytotic vesicles and thereby promotes the escape of lysosome-entrapped compounds. To improve its potency and cell specificity, a targeted prodrug of colchicine was s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f1e88312965d9e978aa4fb90161707
https://doi.org/10.1002/cbic.200300582
https://doi.org/10.1002/cbic.200300582
Autor:
Erik A.L. Biessen, Sabine M.W. van Rossenberg, Erwin Kieviet, Leo A. J. M. Sliedregt, Theo J.C. Van Berkel, Patrick C.N. Rensen, Steven H. van Leeuwen, Michiel Ferns
Publikováno v:
Journal of Biological Chemistry. 276:37577-37584
The asialoglycoprotein receptor (ASGPr) on hepatocytes plays a role in the clearance of desialylated proteins from the serum. Although its sugar preference (N-acetylgalactosamine (GalNAc) >> galactose) and the effects of ligand valency (tetraantennar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22753ecf56e18132c6f541e6babd1a7
https://doi.org/10.1074/jbc.m101786200
https://doi.org/10.1074/jbc.m101786200
Autor:
Sabine M.W. van Rossenberg, P. Anton van der Merwe, Christina Piperi, Gijs A. van der Marel, Theo J.C. Van Berkel, A. Rob P. M. Valentijn, Johan Kuiper, Leo A. J. M. Sliedregt, Reshma Autar, Erik A.L. Biessen, Jacques H. van Boom
Publikováno v:
Bioorganic & Medicinal Chemistry. 9:85-97
CD22 is a cell-surface glycoprotein uniquely located on mature B-cells and B-cell derived tumour cells. Current evidence suggests that binding of endogenous ligands to CD22 leads to modulation of B-cell activation by antigen. Incidentally, however, B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::accc09fbac93cf881f13f2dadd26d50d
https://doi.org/10.1016/s0968-0896(00)00224-8
https://doi.org/10.1016/s0968-0896(00)00224-8
Autor:
Erik A.L. Biessen, Tom J.M. Molenaar, Sabine M.W. van Rossenberg, Cornelis F. M. Sier, Lukas J. A. C. Hawinkels, Chantal C. M. Appeldoorn, Eveline S.M. de Jonge-Muller, Theo J.C. Van Berkel
Publikováno v:
Biochemical and biophysical research communications. 364(3)
In this report, we describe a novel phage display strategy for the identification of dedicated protease inhibiting peptides, based on degradation-aided enrichment of protease resistant phages. Phages were directly incubated with a range of phage-degr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443fb1f2b9c01e22ebec88cf75c0c565
https://pubmed.ncbi.nlm.nih.gov/17959143
https://pubmed.ncbi.nlm.nih.gov/17959143
Autor:
Erik A.L. Biessen, Karen Sliedregt-Bol, Theo J.C. Van Berkel, Jacques H. van Boom, Nico J. Meeuwenoord, Gijs A. van der Marel, Sabine M.W. van Rossenberg
Publikováno v:
Journal of Biological Chemistry, 277(48), 45803-45810
The transfection ability of nonviral gene therapy vehicles is generally hampered by untimely lysosomal degradation of internalized DNA. In this study we describe the development of a targeted lysosome disruptive element to facilitate the escape of DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06023892fc07ed9986e5f1d736b3642e
https://hdl.handle.net/1887/50012
https://hdl.handle.net/1887/50012
Autor:
Theo J.C. Van Berkel, Christina Piperi, Anton van der Merwe, Johan Kuiper, Reshma Autar, Erik A.L. Biessen, Leo A. J. M. Sliedregt, Sabine M.W. van Rossenberg
Publikováno v:
The Journal of biological chemistry. 276(16)
B-cell-specific CD22 is a member of a group of cell adhesion molecules within the immunoglobulin superfamily that display binding to glycans with terminal sialic acid residues. Binding of endogenous ligands to CD22 triggers B-cell activation and prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed775ff538df6e0f12c201e51c2bd7e0
https://pubmed.ncbi.nlm.nih.gov/11152460
https://pubmed.ncbi.nlm.nih.gov/11152460