Zobrazeno 1 - 10
of 315
pro vyhledávání: '"Sabine L Flitsch"'
Autor:
Melissa Greenwood, Patricia Murciano-Martinez, Janet Berrington, Sabine L Flitsch, Sean Austin, Christopher Stewart
Publikováno v:
Microbial Cell, Vol 11, Pp 221-234 (2024)
Human breastmilk is composed of many well researched bioactive components crucial for infant nutrition and priming of the neonatal microbiome and immune system. Understanding these components gives us crucial insight to the health and wellbeing of in
Externí odkaz:
https://doaj.org/article/19cbad3120dc4fbeb6927aed5efb0922
Autor:
Mina-Olga Aletrari, Craig McKibbin, Helen Williams, Vidya Pawar, Paola Pietroni, J Michael Lord, Sabine L Flitsch, Roger Whitehead, Eileithyia Swanton, Stephen High, Robert A Spooner
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22713 (2011)
The small molecule Eeyarestatin I (ESI) inhibits the endoplasmic reticulum (ER)-cytosol dislocation and subsequent degradation of ERAD (ER associated protein degradation) substrates. Toxins such as ricin and Shiga/Shiga-like toxins (SLTx) are endocyt
Externí odkaz:
https://doaj.org/article/5d423c88ef58419e80caaf4f9129e3c2
Autor:
Anna Cioce, Beatriz Calle, Tatiana Rizou, Sarah C. Lowery, Victoria L. Bridgeman, Keira E. Mahoney, Andrea Marchesi, Ganka Bineva-Todd, Helen Flynn, Zhen Li, Omur Y. Tastan, Chloe Roustan, Pablo Soro-Barrio, Mahmoud-Reza Rafiee, Acely Garza-Garcia, Aristotelis Antonopoulos, Thomas M. Wood, Tessa Keenan, Peter Both, Kun Huang, Fabio Parmeggian, Ambrosius P. Snijders, Mark Skehel, Svend Kjær, Martin A. Fascione, Carolyn R. Bertozzi, Stuart M. Haslam, Sabine L. Flitsch, Stacy A. Malaker, Ilaria Malanchi, Benjamin Schumann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Changes in glycoprotein expression are correlates of disease, but secreted glycoproteins cannot be accurately traced to their cell line of origin. Here, the authors develop a strategy to chemically tag and profile glycoproteins in a cell line-specifi
Externí odkaz:
https://doaj.org/article/32c82b244eab4f4ebf7b10a1ff93a4d5
Autor:
Emily E. Kempa, James L. Galman, Fabio Parmeggiani, James R. Marshall, Julien Malassis, Clement Q. Fontenelle, Jean-Baptiste Vendeville, Bruno Linclau, Simon J. Charnock, Sabine L. Flitsch, Nicholas J. Turner, Perdita E. Barran
Publikováno v:
JACS Au, Vol 1, Iss 4, Pp 508-516 (2021)
Externí odkaz:
https://doaj.org/article/34a43ef107ba44e88b736b23d77fadc9
Autor:
Christopher R. B. Swanson, Grayson J. Ford, Ashley P. Mattey, Léa Gourbeyre, Sabine L. Flitsch
Publikováno v:
ACS Central Science. 9:103-108
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdb0dec7c7341e81652bbd9c27895738
https://doi.org/10.1021/acscentsci.2c01169
https://doi.org/10.1021/acscentsci.2c01169
Publikováno v:
Green Chemistry. 25:2958-2970
The state-of-the-art of biocatalytic amide bond formation is discussed with the help of a manually curated database of enzymatic amidation reactions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e90077774af541918e319c069a7bce34
https://doi.org/10.1039/d3gc00456b
https://doi.org/10.1039/d3gc00456b
Autor:
Christian Schnepel, Laura Rodríguez Pérez, Yuqi Yu, Antonio Angelastro, Rachel S. Heath, Max Lubberink, Francesco Falcioni, Keith Mulholland, Martin A. Hayes, Nicholas J. Turner, Sabine L. Flitsch
Publikováno v:
Nature Catalysis. 6:89-99
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59654c40a55d5f22ae9362ac4dd855eb
https://doi.org/10.1038/s41929-022-00889-x
https://doi.org/10.1038/s41929-022-00889-x
Autor:
Robert J. Young, Sabine L. Flitsch, Michael Grigalunas, Paul D. Leeson, Ronald J. Quinn, Nicholas J. Turner, Herbert Waldmann
Publikováno v:
JACS Au. 2:2400-2416
The case for a renewed focus on Nature in drug discovery is reviewed; not in terms of natural product screening, but how and why biomimetic molecules, especially those produced by natural processes, should deliver in the age of artificial intelligenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb98d68f1730913b33475639eeab977
https://doi.org/10.1021/jacsau.2c00415
https://doi.org/10.1021/jacsau.2c00415
Autor:
Grayson J. Ford, Christopher R. Swanson, Ruth T. Bradshaw Allen, James R. Marshall, Ashley P. Mattey, Nicholas J. Turner, Pere Clapés, Sabine L. Flitsch
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Amino-polyols represent attractive chemical building blocks but can be challenging to synthesize because of the high density of asymmetric functionalities and the need for extensive protecting-group strategies. Here we present a three-component strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ffbeefea1cbae2310353dfbf3b157de
https://doi.org/10.1021/jacsau.2c00374
https://doi.org/10.1021/jacsau.2c00374
Autor:
Antonio Angelastro, Alexey Barkhanskiy, William R. F. Goundry, Perdita Barran, Sabine L. Flitsch
Chemo-selective and site-specific modifications of proteins are fundamental to the advancement of biological and pharmaceutical sciences, from understanding the basis of cellular biology to development of biotherapeutics. Recent successes in bioconju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bcb6f452ca354b12a07e5ede79190c5
https://doi.org/10.26434/chemrxiv-2023-msrdw
https://doi.org/10.26434/chemrxiv-2023-msrdw
