Výsledky vyhledávání - "Sabine Kuznia"

Akademický článek

Vitamin D supplementation to the older adult population in Germany has the cost‐saving potential of preventing almost 30 000 cancer deaths per year

Autor: Tobias Niedermaier, Thomas Gredner, Sabine Kuznia, Ben Schöttker, Ute Mons, Hermann Brenner

Publikováno v: Molecular Oncology, Vol 15, Iss 8, Pp 1986-1994 (2021)

Recent meta‐analyses of randomized controlled trials (RCTs) have demonstrated significant reduction in cancer mortality by vitamin D supplementation. We estimated costs and savings for preventing cancer deaths by vitamin D supplementation of the po

Externí odkaz: https://doaj.org/article/bb735c1209184183b7636f710f4b25ea

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Akademický článek

Protocol of the VICTORIA study: personalized vitamin D supplementation for reducing or preventing fatigue and enhancing quality of life of patients with colorectal tumor - randomized intervention trial

Autor: Ben Schöttker, Sabine Kuznia, Dana Clarissa Laetsch, David Czock, Annette Kopp-Schneider, Reiner Caspari, Hermann Brenner

Publikováno v: BMC Cancer, Vol 20, Iss 1, Pp 1-16 (2020)

Abstract Background Cancer-related fatigue represents one major cause of reduced quality of life in cancer patients and can seriously affect the physical, emotional, and cognitive functioning impeding coping with the disease. Options for effective tr

Externí odkaz: https://doaj.org/article/ca4784f5ef484b969697daf7ce6ce7f3

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Akademický článek

Efficacy of vitamin D3 supplementation on cancer mortality in the general population and the prognosis of patients with cancer: protocol of a systematic review and individual patient data meta-analysis of randomised controlled trials

Autor: Hermann Brenner, Ben Schöttker, Sabine Kuznia

Publikováno v: BMJ Open, Vol 11, Iss 1 (2021)

Introduction Vitamin D insufficiency is much more common among patients with cancer than the general population. Previous meta-analyses of controlled trials showed an approximately 15% reduction of cancer mortality by vitamin D supplementation compar

Externí odkaz: https://doaj.org/article/ff59a4935f6348b88b83771597d94d42

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Real‐world evidence for the effectiveness of vitamin D supplementation in reduction of total and cause‐specific mortality

Autor: Sha Sha, Thi Mai Ngoc Nguyen, Sabine Kuznia, Tobias Niedermaier, Anna Zhu, Hermann Brenner, Ben Schöttker

Publikováno v: Journal of Internal Medicine. 293:384-397

Meta-analyses of randomized controlled trials (RCTs) have demonstrated the efficacy of vitamin D supplementation for reduced cancer mortality, all-cause mortality, and respiratory tract infections. However, whether and to what extent this translates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482bca3fe398238b44f154899c29141f
https://doi.org/10.1111/joim.13578

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Efficacy of vitamin D(3) supplementation on cancer mortality: Systematic review and individual patient data meta-analysis of randomised controlled trials

Publikováno v: Ageing Res Rev

To evaluate the effect of vitamin D(3) supplementation on cancer mortality in the general population and on prognosis in cancer patients, a systematic review and meta-analysis of randomised, placebo-controlled trials (RCTs) and individual patient dat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05e99892c19ba98c923138d133d0c24
https://europepmc.org/articles/PMC10214278/

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Efficacy and Safety of a Personalized Vitamin D3 Loading Dose Followed by Daily 2000 IU in Colorectal Cancer Patients with Vitamin D Insufficiency: Interim Analysis of a Randomized Controlled Trial

Autor: Sabine Kuznia, David Czock, Annette Kopp-Schneider, Reiner Caspari, Harald Fischer, Dana Clarissa Laetsch, Marija Slavic, Hermann Brenner, Ben Schöttker

Publikováno v: Nutrients; Volume 14; Issue 21; Pages: 4546

A personalized vitamin D3 loading dose has not yet been tested in cancer patients. This interim analysis of the randomized, placebo-controlled VICTORIA trial analyzed the first recruited 74 German adults with nonmetastatic colorectal cancer, a tumor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4675b81ef61ac3c6fe077923b2cc55

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Consistent Inverse Associations of Total, “Bioavailable”, Free, and “Non-Bioavailable” Vitamin D with Incidence of Diabetes among Older Adults with Lower Baseline HbA1c (≤6%) Levels

Autor: Brenner, Anna Zhu, Sabine Kuznia, Tobias Niedermaier, Bernd Holleczek, Ben Schöttker, Hermann

Publikováno v: Nutrients; Volume 14; Issue 16; Pages: 3282

Background: Serum 25-hydroxyvitamin (25(OH)D) levels are inversely associated with risk of diabetes. The “free hormone hypothesis” suggests potential effects to be mainly related to concentrations of “bioavailable” and free rather than total

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::39d0672321c4be3a8e726b5fec84b7f3

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Vitamin D-binding protein, total, 'nonbioavailable,' bioavailable, and free 25-hydroxyvitamin D, and mortality in a large population-based cohort of older adults

Autor: Anna Zhu, Sabine Kuznia, Tobias Niedermaier, Bernd Holleczek, Ben Schöttker, Hermann Brenner

Publikováno v: Journal of internal medicineReferences. 292(3)

Epidemiological studies consistently find low concentrations of 25-hydroxyvitamin D (25(OH)D) in blood to be associated with increased mortality, and a recent large-scale Mendelian randomization study strongly supports a causal relationship among ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::becc995e663d7e6c5053a5925393d8cd
https://pubmed.ncbi.nlm.nih.gov/35373871

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Distribution and Determinants of Vitamin D-Binding Protein, Total, 'Non-Bioavailable', Bioavailable, and Free 25-Hydroxyvitamin D Concentrations among Older Adults

Autor: Anna Zhu, Hermann Brenner, Sabine Kuznia, Tobias Niedermaier, Ben Schöttker, Bernd Holleczek

Publikováno v: Nutrients
Volume 13
Issue 11
Nutrients, Vol 13, Iss 3982, p 3982 (2021)

Background: serum 25-hydroxyvitamin D (25(OH)D) (“total 25 OH(D)”) is the most commonly used indicator of vitamin D status. However, 25(OH)D is mostly bound to the vitamin D binding protein (VDBP) or albumin in blood, and it has been suggested th

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Potential of Vitamin D Food Fortification in Prevention of Cancer Deaths—A Modeling Study

Autor: Thomas Gredner, Ute Mons, Ben Schöttker, Sabine Kuznia, Hermann Brenner, Tobias Niedermaier

Publikováno v: Nutrients, Vol 13, Iss 3986, p 3986 (2021)
Nutrients
Volume 13
Issue 11

Meta-analyses of randomized controlled trials (RCTs) have estimated a 13% reduction of cancer mortality by vitamin D supplementation among older adults. We evaluated if and to what extent similar effects might be expected from vitamin D fortification

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29625629e0702875b626b4d789e587ec
https://www.mdpi.com/2072-6643/13/11/3986

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