Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Sabine Knappe"'
Autor:
Tjerk Feenstra, Gerald Schrenk, Friedrich Scheiflinger, Michael Dockal, Rudolf Hartmann, Sabine Knappe
Publikováno v:
Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 31(6)
Accurate monitoring of coagulation, needed for optimal management of patients with haemophilia A with inhibitors, presents a challenge for treating physicians. Although global haemostatic assays may be used in this population, their utility with nonf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060d3684430a0367f986d935d116212b
https://pubmed.ncbi.nlm.nih.gov/32467424
https://pubmed.ncbi.nlm.nih.gov/32467424
Autor:
Catherine Quinn, Sabine Knappe, Zhenqing Zhang, Christina M. Szabo, Friedrich Scheiflinger, James Catarello, Susanne Till, G. Joseph Ray, Michael Dockal
Publikováno v:
Carbohydrate Polymers. 115:677-685
Fucoidans are complex sulfated polysaccharides extracted from brown algae. Depending on the concentration, they have been shown to stimulate and inhibit blood coagulation in vitro. Promotion of coagulation is mediated by blocking tissue factor pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06f287d0e870e05de92c23761349aac
https://doi.org/10.1016/j.carbpol.2014.09.001
https://doi.org/10.1016/j.carbpol.2014.09.001
Autor:
F. Scheiflinger, Monika E Gorczyca, Bernd Jilma, Michael Dockal, Sabine Knappe, Ulla Derhaschnig, Michael Palige, Rudolf Hartmann
Publikováno v:
Thrombosis and Haemostasis. 109:450-457
SummaryTissue factor pathway inhibitor (TFPI) is a major inhibitor of coagulation. We therefore hypothesised that high plasmatic TFPI levels are associated with impaired ex vivo clotting in a model of acquired haemophilia. Blood samples were collecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717d87131861031b7834652cad491220
https://doi.org/10.1160/th12-07-0529
https://doi.org/10.1160/th12-07-0529
Publikováno v:
Blood. 130:90-90
Introduction: Emicizumab (ACE910), an antibody to FIX(a) and FX(a), is currently under investigation for treatment of hemophilia with inhibitors. In a phase III trial, two thromboembolic complications and three cases of microangiopathy were reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::276fbf2e537819c0703c60583e017b8c
https://doi.org/10.1182/blood.v130.suppl_1.90.90
https://doi.org/10.1182/blood.v130.suppl_1.90.90
Publikováno v:
Applied and Environmental Microbiology. 74:294-299
In this study, the feasibility of fluorescence lifetime imaging (FLIM) for measurement of RNA:DNA ratios in microorganisms was assessed. The fluorescence lifetime of a nucleic acid-specific probe (SYTO 13) was used to directly measure the RNA:DNA rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7212b78c596f47dfba04edcee68096
https://doi.org/10.1128/aem.01806-07
https://doi.org/10.1128/aem.01806-07
Publikováno v:
Journal of Biological Chemistry. 279:34464-34471
Corin is a type II transmembrane serine protease and functions as the proatrial natriuretic peptide (pro-ANP) convertase in the heart. In the extracellular region of corin, there are two frizzled-like cysteine-rich domains, eight low density lipoprot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1bd51a960908fe85f3ef724b1e573d0
https://doi.org/10.1074/jbc.m405041200
https://doi.org/10.1074/jbc.m405041200
Publikováno v:
Journal of Biological Chemistry. 278:52363-52370
Corin is a cardiac transmembrane serine protease. In cell-based studies, corin converted pro-atrial natriuretic peptide (pro-ANP) to mature ANP, suggesting that corin is potentially the pro-ANP convertase. In this study, we evaluated the importance o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b27ce963454d28d6eb637320f602769
https://doi.org/10.1074/jbc.m309991200
https://doi.org/10.1074/jbc.m309991200
Autor:
Friedrich Scheiflinger, Sabine Knappe, Leonard A. Valentino, Bruce M. Ewenstein, Rudolf Hartmann, Brahm Goldstein
Publikováno v:
Blood. 128:4952-4952
Background: Investigational non-factor products, such as ACE 910 (Emicizumab), offer potential new treatment options for hemophilia patients with inhibitors. However, their uncertain and unregulated mechanisms of action raise multiple concerns around
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da072ccaecd36236ea0a68c6f2b7f789
https://doi.org/10.1182/blood.v128.22.4952.4952
https://doi.org/10.1182/blood.v128.22.4952.4952
Autor:
Zhenqing Zhang, Christina M. Szabo, Sabine Knappe, Michael Dockal, Cong Jiang, Sabrina Reutterer, Friedrich Scheiflinger, Susanne Till
Publikováno v:
Thrombosis and haemostasis. 111(3)
SummaryFucoidan is a highly complex sulfated polysaccharide commonly extracted from brown seaweed. In addition to their many biological activities, fucoidans have recently been demonstrated to inhibit or increase coagulation at different concentratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c22adf9b92f9685beaa2b5189203a413
https://pubmed.ncbi.nlm.nih.gov/24285223
https://pubmed.ncbi.nlm.nih.gov/24285223
Publikováno v:
Nature protocols. 7(4)
The labeling of biomolecules has become standard practice in molecular biosciences. Modifications are used for detection, sorting and isolation of small molecules, complexes and entire cells. We have recently reported a method for introducing interna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f482e172a74fbecddf104d4296bd5f
https://pubmed.ncbi.nlm.nih.gov/22402634
https://pubmed.ncbi.nlm.nih.gov/22402634